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Information for module BIOL3011

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Module code:BIOL3011(Add to my personalised list)
Title:Advanced Human Genetics 2: Further Topics
Credit value:.5
Division:Division of Biosciences
Module organiser:Prof Andres Ruiz-Linares
Organiser's location:Biological Sciences
Organiser's email:a.ruizlin@ucl.ac.uk
Available for students in Year(s):3,
Module prerequisites:BIOL3013 Advanced Human Genetics (1): Single Gene Disorders. PLEASE NOTE BIOL3011 IS NOT AVAILABLE AS AN OPTIONAL MODULE - IT IS ONLY AVAILABLE TO 3RD YEAR STUDENTS WHO HAVE IT AS CORE FOR THEIR DEGREE PROGRAMME. 
Module outline:The course focuses on the analysis of common "complex" diseases which, though they are partly genetic, are not inherited in a 'simple' Mendelian fashion. A general introduction to some of the main statistical methods and genetic concepts used in the analysis of these diseases is provided. A substantial part of the course is devoted to a detailed discussion of selected case-studies. The phenotypes chosen vary from year to year, but can include examples such as eye and neurological disorders, pharmacogenetics, cardiovascular disease, psychiatric genetics, mitochondrial disorders, and the molecular genetics of pain perception.  
Module aims:To provide students with - A basic understanding of the main statistical methods used to analyse complex disorders. - An overview of the main experimental approaches currently in use for the genomic analysis of complex phenotypes. - An illustration of some of the main finding so far obtained for selected diseases. - An appreciation of potential future implications of research on common diseases.  
Module objectives:Knowledge: parametric and non-parametric linkage analysis, sib-pair analysis, association studies, TDT, case-control studies, GWAS, linkage disequilibrium in human populations, molecular pathogenesis of the disorders chosen as examples, pharmacogenetics, personalized medicine.  
Key skills provided by module:Skills: use of web resources and bioinformatic tools for genome analysis. 
Module timetable:https://cmis.adcom.ucl.ac.uk:4443/timetabling/moduleTimet.do?firstReq=Y&moduleId=BIOL3011 
Module assessment:Unseen two-hour written examination 75.00%.
20% coursework and 5% problem solving 25.00%.
 
Notes: 
Taking this module as an option?: 
Link to virtual learning environment(registered students only) 
Last updated:2012-07-17 15:39:37 by ucbtksr