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Information for module PHARG004

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Module code:PHARG004(Add to my personalised list)
Title:Receptor Mechanisms
Credit value:15
Division:Division of Biosciences
Module organiser:Prof Alasdair Gibb
Organiser's location:Medical Sciences Building, Room G41.
Organiser's email:a.gibb@ucl.ac.uk
Available for students in Year(s):1,
Module prerequisites:Please consult module organiser. Suitable background required in Biochemistry, Physiology and Pharmacology. 
Module outline:This course is about the mechanisms involved in the generation of a response following receptor activation, either by a natural hormone or neurotransmitter or by drug action, and how drugs may interfere with receptor-mediated responses. Mechanisms involving ligand-gated ion channels, voltage-dependent calcium channels and potassium channels, G-proteins, second messengers (e.g. inositol phosphates, diacylglycerol) and cellular kinases and phosphatases are then considered in detail, together with the role of calcium. A final section draws these themes together by examining integrated cell responses such as the control of the release of insulin from the pancreas. The course material is supplemented by group presentations and discussion of selected research papers related to the core lectures and by the preparation of an essay by each student.  
Module aims:The course aims to teach students about the mechanisms involved in the responses that result from activation of neurotransmitter and hormone receptors.  
Module objectives:On completion of the course, students should have a detailed knowledge of the following topics: 1)Mechanism of action of G-protein coupled receptors 2)Secondary messengers: Ca2+, IP3, protein kinases and phosphatases 3)Ligand gated ion channel receptor mechanisms 4)Voltage-gated ion channel mechanisms  
Key skills provided by module:Presentation skills Analysis and interpretation of research papers  
Module timetable:https://cmis.adcom.ucl.ac.uk:4443/timetabling/moduleTimet.do?firstReq=Y&moduleId=PHARG004 
Module assessment:One essay 15.00%.
Unssen three-hour written examination 85.00%.
 
Notes: 
Taking this module as an option?: 
Link to virtual learning environment(registered students only) 
Last updated:2014-02-19 14:16:47 by