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Information for module GENEG006

This module is available for: The current academic year and The next academic year(provisional)

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Module code:GENEG006(Add to my personalised list)
Title:Understanding Bioinformatics Resources and Their Application
Credit value:15
Division:Division of Biosciences
Module organiser:Dr Ruth Lovering
Organiser's location:Rayne Building
Organiser's email:r.lovering@ucl.ac.uk
Available for students in Year(s):
Module prerequisites:Available to MSc Genetics of Human Disease Students Only  
Module outline:Competency in genomic and proteomic resources is an essential skill for human disease genetic researchers, in this the post-genome era. This module will enable students to experience first-hand how the annotation of the human genome is achieved and understand the uses and limitations of a wide range of freely available online resources. The course has four themes: (1) Online biological databases and their use for gene/SNP mapping, coding region identification, data extraction, including Ensembl, EntrezGene, UniProt, Biomart, OMIM, ChEBI, (2) Gene Ontology annotation and application, (3) Analysis of protein sequences and structure, including sequence alignment, structural and/or functional motif recognition, structure prediction, protein evolution, (4) Regulation of gene transcription, providing an introduction to this research area and the methods used to characterise proteins involved in gene regulation. Students will be required to undertake their own literature review of a limited number of genes, or biological field and will gain an insight into the application of ontologies. Gene Ontology is an established resource for linking the accrued knowledge about individual genes to each gene record in a database and an invaluable resource for the analysis of data derived from a wide variety of high-throughput methodologies.  
Module aims:To gain experience in a wide variety of online genomic databases and resources. To learn how to review and evaluate the scientific literature describing a gene of interest. To achieve a comprehensive understanding of GO. To gain an insight into the regulation of gene transcription.  
Module objectives:: To understand how and when to use a variety of online genomic and proteomic databases and resources. To understand how to critically evaluate scientific papers. To develop independent investigative skills and presentation skills. To understand the principles of gene regulation and its relevance to human disease. To understand how the GO database is populated with annotations and how it can be used for the analysis of high-throughput data.  
Key skills provided by module:Presentation skills - Scientific report writing – Competent use of online biological resources  
Module timetable:https://cmis.adcom.ucl.ac.uk:4443/timetabling/moduleTimet.do?firstReq=Y&moduleId=GENEG006 
Module assessment:Independent project: SNP report (1,500 words) 70.00%.
Gene summary presentation (10 minutes) 20.00%.
Seen three-hour multiple choice test 10.00%.
 
Notes: 
Taking this module as an option?: 
Link to virtual learning environment(registered students only)http://moodle.ucl.ac.uk/course/view.php?id=10301 
Last updated:2014-03-06 15:03:21 by