Information for module GENEG006
This module is available for: The current academic year and The next academic year(provisional)
If you're a member of UCL you can add this module to your personalised course list
This information is for guidance only. If you are a UCL undergraduate interested in studying one of these courses, you must seek permission from both the providing department and your 'home' department. Appearance in this database is not a guarantee that a course is running in any particular academic year.
|Module code:||GENEG006(Add to my personalised list)|
|Title:||Understanding Bioinformatics Resources and Their Application|
|Division:||Division of Biosciences|
|Module organiser:||Dr Ruth Lovering|
|Organiser's location:||Rayne Building|
|Available for students in Year(s):|
|Module prerequisites:||Available to MSc Genetics of Human Disease Students Only|
|Module outline:||Competency in genomic and proteomic resources is an essential skill for human disease genetic researchers. This module will enable students to experience first-hand how the annotation of the human genome is achieved and understand the uses and limitations of a wide range of freely available online resources. The course has four themes: (1) Online biological databases and their use for gene/SNP mapping, coding region identification, data extraction, including Ensembl, NCBIGene, UniProt, Biomart, OMIM, ChEBI, (2) Gene Ontology annotation and application, (3) Analysis of protein sequences and structure, including sequence alignment, structural and/or functional motif recognition, structure prediction, protein evolution, (4) Regulation of gene transcription, providing an introduction to this research area and the methods used to characterise proteins involved in gene regulation. Students will be required to undertake their own literature review of a limited number of genes, or biological field and will gain an insight into the application of ontologies.|
|Module aims:||To provide students with experience in a wide variety of online genomic and proteomic databases and resources and in the evaluation the scientific literature describing a gene of interest To provide students with a basic knowledge of: Gene Ontology and how it can be used for the analysis of high-throughput data. How a protein sequence relates to its function. The principles of gene regulation and their relevance to human disease.|
|Module objectives:||: To understand how and when to use a variety of online genomic and proteomic databases and resources. To understand how to critically evaluate scientific papers. To develop independent investigative skills and presentation skills. To understand the principles of gene regulation and its relevance to human disease. To understand how the GO database is populated with annotations and how it can be used for the analysis of high-throughput data.|
|Key skills provided by module:||Knowledge: Gene Ontology, protein structure and function, gene regulation. Skills: Genomic and proteomic database use and application, functional analysis tool use, independent investigative skills, paper summation and presentation skills.|
|Module assessment:||Gene summary presentation (10 minutes) 20.00%.|
Independent project: SNP report (1,500 words) 70.00%.
Seen three-hour multiple choice test 10.00%.
|Taking this module as an option?:|
|Link to virtual learning environment(registered students only)||http://moodle.ucl.ac.uk/course/view.php?id=10301|
|Last updated:||2014-07-10 11:28:14 by|