Module Database

Information for module BIOLG011

This module is available for: The current academic year and The next academic year(provisional)

If you're a member of UCL you can add this module to your personalised course list

This information is for guidance only. If you are a UCL undergraduate interested in studying one of these courses, you must seek permission from both the providing department and your 'home' department. Appearance in this database is not a guarantee that a course is running in any particular academic year.


Module code:BIOLG011(Add to my personalised list)
Title:Advanced Human Genetics (2): Complex Disorders
Credit value:15
Division:Division of Biosciences
Module organiser:Prof Andres Ruiz-Linares
Organiser's location:Biological Sciences
Organiser's email:a.ruizlin@ucl.ac.uk
Available for students in Year(s):4,
Module prerequisites:BIOLG014: Advanced Human Genetics (1): Single Gene Disorders 
Module outline:The course focuses on the analysis of common "complex" diseases which, though they are partly genetic, are not inherited in a 'simple' Mendelian fashion. A general introduction to some of the main statistical methods and genetic concepts used in the analysis of these diseases is provided. A substantial part of the course is devoted to a detailed discussion of selected case-studies. The phenotypes chosen vary from year to year, but can include examples such as eye and neurological disorders, pharmacogenetics, cardiovascular disease, psychiatric genetics, mitochondrial disorders, and the molecular genetics of pain perception. 
Module aims:To provide students with - A basic understanding of the main statistical methods used to analyse complex disorders. - An overview of the main experimental approaches currently in use for the genomic analysis of complex phenotypes. - An illustration of some of the main finding so far obtained for selected diseases. - An appreciation of potential future implications of research on common diseases.  
Module objectives: Knowledge: parametric and non-parametric linkage analysis, sib-pair analysis, association studies, TDT, case-control studies, GWAS, linkage disequilibrium in human populations, molecular pathogenesis of the disorders chosen as examples, pharmacogenetics, personalized medicine.  
Key skills provided by module:Skills: use of web resources and bioinformatic tools for genome analysis.  
Module timetable:https://cmis.adcom.ucl.ac.uk:4443/timetabling/moduleTimet.do?firstReq=Y&moduleId=BIOLG011 
Module assessment:Unseen two-hour written examination 65.00%.
Coursework 35.00%.
 
Notes:To register for this module for the 2012/13 academic year please ensure you meet the prerequisites listed above (where applicable) and, if you do, select it using Portico and await Teaching and Parent Department approval. 
Taking this module as an option?:This is a PGT module only 
Link to virtual learning environment(registered students only)https://moodle.ucl.ac.uk/course/view.php?id=1031 
Last updated:2013-03-14 14:54:23 by