Lunch hour lectures repository Spring 2009
- Does rule learning make us human?
- The man who invented the concept of pi: William Jones and his circle
- President Obama and America in the World: from inauguration to action
- The Reception of Homer in Byzantium
- Photodynamic Therapy: using light in a gentle approach to cancer therapy by remote control
- One World Week
- Still no black in the union jack
- Darwin Day
- Modelling how water vapour absorbs light
- Children and the environment: independence or obesity?
- Physiology on top of the world - Xtreme Everest
- The future of Brazil
- Sorry, can you say that again..?
- One person households - a resource time bomb?
- Mimicking tissue growth: towards customised, while-you-wait tissue fabrication
- What have the lawyers ever done for us? Law, culture and international agricultural trade
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Physiology on top of the world - Xtreme Everest
3 December 2008
Dr Mike Grocott (UCL Medicine)
Caudwell Xtreme Everest (CXE) is a large, healthy volunteer field study investigating human adaptation to environmental hypoxia. CXE is a project of the Centre for Altitude Space and Extreme Environment Medicine (CASE Medicine) at University College London. The aim of CASE Medicine is to investigate variability in human adaptation to low oxygen levels (hypoxia) in order to improve understanding of how critically ill patients deal with hypoxia. During April and May 2007 more than 200 individuals were studied as they were progressively exposed to hypobaric hypoxia on the trek to Everest Base Camp at 5,300m. Most of these individuals were volunteers who gave up their holidays to be participants in the study. The remainder was comprised of doctors and scientists, 15 of whom continued the studies as they ascended up to 8,000m. Eight of these investigators reached the summit of Everest and on their descent took the first measurement of arterial oxygen levels above 8,000m. A series of complex physiological measurements were taken in London before departure, in four laboratories in Nepal on the ascent to Everest Base Camp, and in two laboratories high on Mount Everest. The next few years will see whether this new approach to investigating the pathogenesis of critical illness bears fruit.
Page last modified on 03 dec 08 15:04