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Jeffery Lab
Institute of Behavioural Neuroscience

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Kate Jeffery

Kate Jeffery - Lab head

I am a behavioural neuroscientist interested in how sensory information is assembled by the brain into more complex, cognitive representations of the world. My focus is on the “cognitive map”, which is formed by the hippocampus and associated structures and underlies our sense of direction and sense of place. This map is also used to organise memories of life experiences.

My lab studies the cognitive map by recording single neurons from animals exploring space, and trying to decode the signals and understand what information they convey. We also study behaviour in order to determine what an animal “knows” about where it is and where it plans to go. The work will help us understand not just navigation but also cognition more generally, and may have implications for clinical disorders of navigation (topographical disorientation) and memory

Sharada Karanam - Lab manager

Sharada Karanam - Lab manager

I have a PhD and post-doctoral experience in Biotechnology. As laboratory manager of IBN, my responsibilities include managing the day-to-day running of the department and working closely with the Centre Director as well as the financial and professional services team across the Division of Psychology and Language Sciences. I work closely with UCL’s Central Support Services as well.

I very much enjoy the diversity of my role and at IBN; the challenges and opportunities it brings and working with a team of enthusiastic and supportive people.

Roddy Grieves - postdoc

Roddy Grieves - Postdoc


I’m a postdoctoral researcher at the Institute of Behavioral Neuroscience, University College London. My current experiments involve recording neurons at the single cell level in the rat hippocampus and entorhinal cortex while these animals freely explore complex environments. Our experiments seek to determine how the activity of these cells can represent 2D spatial locations and how these representations may extend into three dimensions.
Eleonore Duvelle - postdoc

Eléonore Duvelle - Postdoc

 Through learning and memorisation of relevant information, our brain learns to make predictions about the world and take (hopefully) appropriate decisions. My general aim is to try and understand how declarative memories are stored in neural networks and how they are used to influence complex decisions. More specifically, I study “place cells”, hippocampal neurons thought to encode spatial memories. Recording the activity of these cells in rats performing complex navigation tasks (for example in our “hexamaze”) should help us unravel the mechanisms of navigation in complex space and the processes through which memory influences future decisions.
Hector Page - postdoc

Hector Page - Postdoc

My research focuses on using computational modelling to explain how the brain processes space. As part of the Jeffery Lab, I am specifically interested in spatially-responsive cells such as Head Direction, Grid, and Place cells. I am a firm believer in the value of data-driven model formation, and model-driven data collection. As such, I work in close collaboration with experimenters within the Jeffery Lab, in order to build computational models which can help to explain their data in the context of what we already know about spatial processing, and to suggest future hypotheses for empirical testing.

More broadly, I am interested in understanding the responses of single neurons within a systems-level context. I believe spatial processing, with well-defined single neuron responses, is an ideal field in which to attempt this.

James Street - PhD student

James Street - PhD student

My work concerns how information about visual landmark is integrated into the head direction signal.  To probe this, I utilise a combination of lesions, optogenetics and chronic electrophysiology in behaving animals to ask whether postsubicular head direction cells can be controlled by visual landmarks in the absence of visual processing by the lateral geniculate nucleus.
Han Yin Cheng - PhD student

Han Cheng - PhD student

Head direction (HD) cells are cells that fire when an animal’s head faces a specific direction. Recently we have identified subpopulations of HD cells in the retrosplenial cortex (RSC) that differ in their responsiveness to the visual panorama. The most visually responsive HD cells are located in the dysgranular subregion of RSC.

Using a combination of neuroanatomical, optogenetics and electrophysiological techniques, I am interested in dissecting the neural circuit underlying these differing responses and develop an understanding of the mechanism by which this could happen.

Ningyu Zhang - PhD student

Ningyu Zhang - PhD student

It is not yet known how an animal’s internal sense of direction is influenced by stability of environmental cues, and how it might translate between different reference frames for navigation. To address such questions, my PhD study works on head direction signals in retrosplenial cortex of rats within a context combing behavioural/electrophysiological recordings, and extends to application of chemo/optogenetic approaches to selectively control the activity of brain regions involved in navigation.
Eleonora Lomi


Eleonora Lomi - PhD student

  Understanding the neural mechanisms underlying spatial cognition in rodents represents a crucial step to uncover global processes governing learning and adaptive behaviour in humans, due to the association between places, events and goals required to perform spatial tasks. Using a combination of behavioural and electrophysiological techniques, my PhD research investigates how the anteroventral nucleus of the anterior thalamus (AVN) contributes to our ability to learn new information. This research will add to the already well characterised mapping of head direction cells, and will enhance our understanding about the information that is available to support learning and navigation within the hippocampal system, in which the AVN remains an uncharacterised, yet critical structure.
   
Andrea Alenda Research fellow, Electrical Engineering Dept, Imperial College London
Research fellow, Electrical Engineering Dept, Imperial College London
Michael Anderson
Software designer
Software designer
Caswell Barry
Postdoctoral position with John O'Keefe and Neil Burgess
Sir Henry Dale Fellow at the CDB Dept, UCL
Subhojit Chakraborty
Research associate at Dept. Experimental Psychology, University of Oxford Research associate at the Dept. of Bioengineering, Imperial College London
Giulio Casali Postdoctoral fellow, UCL with Caswell Barry  Postdoctoral fellow, UCL with Caswell Barry
Lin Lin Ginzberg Wellcome journalism student
BBC Science researcher
Robin Hayman
Teaching fellow, Dept. Psychology, UCL
Postdoctoral Fellow, UCL, with Neil Burgess
 Pierre-Yves Jacob  Postdoctoral Fellow, Marseille  Postdoctoral Fellow. Marseille
Aleks Jovalekic Postdoctoral Fellow, Institute of Neuroinformatics, University of Zurich Publication manager at Piramar Imaging
Bex Knight Lecturer, Dept. of Psychology, University of Hertfordshire Lecturer, Dept. of Psychology, University of Hertfordshire
Yave Lozano Postdoctoral fellow Institute of Clinical Neurobiology, Julius Maximilian University of Würzburg
Gabriel Makdah  MSc student  Zugaro lab, paris
Liz Marozzi
Executive officer to Head of Division, Psychology and Language Sciences, UCL

Primary PGCE student at the Institute of Education, London
Lori Minini
Departmental Lecturer, University of Oxford
Departmental Lecturer, University of Oxford
 Dot Overington  Science Publishing  Science Publishing
Caitlin Piette
Research and Development Manager, Axona Ltd

Deputy Editor, Lancet Neurology
Sophie Renaudineau Postdoctoral fellow, UCL with Dan Bendor Postdoctoral fellow, UCL with Dan Bendor
Madeleine Verriotis Postdoctoral Fellow, Dept. Neuroscience, Physiology & Pharmacology, UCL Postdoctoral Fellow, Dept. Neuroscience, Physiology & Pharmacology, UCL
 Aman Saleem Wellcome Sir Henry Dale Fellow, IBN, UCL Wellcome Sir Henry Dale Fellow, IBN, UCL
Jonathan Wilson
Postdoctoral Fellow, MRC Laboratory of Molecular Biology, Cambridge University
Postdoctoral Fellow, MRC Laboratory of Molecular Biology, Cambridge University

Collaborators

Axona, a company that makes electrophysiology equipment for single neuron recording.
Caswell Barry, Sir Henry Dale Fellow at the CDB Dept, UCL
Eleanor Maguire, Wellcome Trust Centre for Neuroimaging
 Anna Mitchell, Wellcome Trust Investigator, University of Oxford
 Aman Saleem, Wellcome Sir Henry Dale Fellow, IBN, UCL
Sam Solomon, Senior Lecturer, IBN
Hugo Spiers, Reader, IBN
Jeremy Skipper, Experimental Psychology, UCL