EyeTherapy Blog News

Athena Vision launches; developing gene therapies for devastating eye diseases

Tue, 24 Nov 2015 11:53:39 +0000

Athena Vision is focused on developing gene therapies for eye diseases based on research conducted at UCL Today sees the launch of Athena Vision Limited a biopharmaceutical company focused on the development of gene therapies to treat a range of devastating eye diseases causing blindness. Launched by UCL Business PLC, the wholly-owned technology transfer company of UCL, […]


Registration for Retina Day 2015 Now Open!

Wed, 10 Jun 2015 11:37:25 +0000

It’s that time once agin for our annual research day for patients and the public. Retina Day 2015 is a free, one day event is organised by the Gene and Cell Therapy Group, UCL Institute of Ophthalmology and NIHR Moorfields Biomedical Research Centre. Come along to: * Hear about some of the latest innovations in research […]


UCL RPE65 Gene Therapy Trial Shows Benefit in People with Leber Congenital Amaurosis Type 2 for up to Three Years After Treatment

Tue, 05 May 2015 14:44:39 +0000

We are delighted to be able to announce that yesterday, Monday 4th May, the long-term results of our RPE65 gene therapy trial for Leber Congenital Amaurosis Type 2 (LCA2) were published in the prestigious New England Journal of Medicine. Begun in 2007, this was the world’s first-in-human trial of gene therapy to treat an inherited […]


Clinical trials

Long-term effect of gene therapy on Leber's congenital amaurosis. Bainbridge JW, Mehat MS, Sundaram V, Robbie SJ, Barker SE, Ripamonti C, Georgiadis A, Mowat FM, Beattie SG, Gardner PJ, Feathers KL, Luong VA, Yzer S, Balaggan K, Viswanathan A, de Ravel TJ, Casteels I, Holder GE, Tyler N, Fitzke FW, Weleber RG, Nardini M, Moore AT, Thompson DA, Petersen-Jones SM, Michaelides M, van den Born LI, Stockman A, Smith AJ, Rubin G, Ali RR. N Engl J Med. 2015; 372 (20): 1887-97

Effect of gene therapy on visual function in adults with Leber Congenital Amaurosis. JWB Bainbridge, AJ Smith, SE Barker, S Robbie, R Henderson, KS Balaggan, A Viswanathan, GE Holder, A Stockman, N Tyler, S Petersen-Jones, SS Bhattacharya, AJ Thrasher, FW Fitzke, BJ Carter, GS Rubin, AT Moore and RR Ali N Engl J Med. 2008; 358 (21): 2231-9

Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector. HB Gaspar, KL Parsley, S Howe, D King , KC Gilmour, J Sinclair, G Brouns, M Schmidt, C Von Kalle, T Barington, M Jakobsen, HO Christensen, A Al Ghonaium, HN White, JL Smith, RJ Levinsky, RR Ali, C Kinnon and AJ Thrasher Lancet 2004; 364 (9452): 2181-7

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