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Eye Therapy News

Professor Ali honoured for his contribution to research into retinal disease

Mon, 08 Sep 2014 12:27:36 +0000

              Professor Robin Ali, PhD, Professor of Human Molecular Genetics and Head of the Department of Genetics, UCL Institute of Opthalmology has been awarded the Pioneer Award for his work in proof-of-concept studies that have demonstrated the feasibility of using gene therapy and cell transplantation to treat dysfunction and degeneration of the cells […]

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Achromatopsia might not be as progressive as previously thought

Mon, 08 Sep 2014 11:17:16 +0000

A recent publication from the UCL Institute of Ophthalmology, Moorfields Eye Hospital, and the Medical College of Wisconsin indicates that for the majority of people with achromatopsia, the condition may not be as progressive as previously suggested. Data from this study by Aboshiha et al. demonstrated that for the majority of people with achromatopsia (a […]

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2 Lazy 2 Run? We’re biking it for blood cancer!

Fri, 29 Aug 2014 09:30:05 +0000

  On Sunday 31 August a group of not so elite athletes from the Gene and Cell Therapy group will be taking part in the London Bikeathon 2014 to raise funds for Leukaemia & Lymphoma Research. The 2 Lazy 2 Run CC will be cycling 52 miles – that’s more than a marathon, no mean feet […]

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The Art of Eyes

Thu, 07 Aug 2014 14:23:19 +0000

The eye is an object of great beauty as shown by the Ophthalmologist in their July/August 2014 issue. This month’s issue features a photo essay called The Art of the Eyes and includes examples of the work from a number research labs capturing the complex and beautiful detail of the eye and its cells. The essay includes images […]

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In memoriam

Tue, 05 Aug 2014 16:02:34 +0000

Dr Yoshiki Sasai (1962 – 2014) It is with great sadness today that we remember and pay tribute to our collaborator Dr Yoshiki Sasai. Yoshiki was a world leading stem cell researcher and Deputy Director of the Riken Center for Developmental Biology in Kobe, Japan. Through his hard work and dedication over many years, Yoshiki […]

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Join the team - vacancies and opportunities

Our research team includes clinicians and scientists of the highest calibre, and our track record of publications and cutting-edge clinical trials demonstrates the impact of our work developing gene and cell therapies for sight loss.

We are pleased to offer the following opportunities:

Click HERE for job vacancies in research


You can also visit the Job Opportunities at UCL page for further opportunities both here and elsewhere at UCL: http://www.ucl.ac.uk/hr/jobs.

Current vacancies:

Research Associate - Ref:1447701

Institute of Ophthalmology, Genetics

Grade 7

Full Time Hours

Salary (inclusive of London allowance): £33,353 - £40,313 per annum

Duties and Responsibilities

The main interest in the Molecular Therapy group is the development of novel therapies for retinal disorders with a major emphasis on translating research into clinical application.  It is one of the largest gene and cellular therapy groups in the country and presently consists of 40 individuals, including consultant ophthalmologists, post-doctoral scientists, clinical research fellows, graduate students and technicians.

Working in close collaboration with other team members, the post holder will be working on the pre-clinical development of new ocular gene therapy protocols using murine models of disease. S/he will evaluate new models of disease, design and create new vectors, and test therapeutic outcomes. In addition the post holder may be asked to participate in other projects within the gene and cell therapy group.

The position is funded until 31 March 2017 in the first instance.

Key Requirements 

The successful applicant will have a post-doctoral degree in a relevant subject, have shown commitment to high quality research and be able to work to a high standard. Previous experience with molecular biology is essential. Experience in cell biological techniques and experience working with gene therapy vectors are desirable.

Closing date for applications: 17:00 GMT on 7 January 2015

Click HERE to apply.


Research Associate - Ref:1447710

Institute of Ophthalmology, Genetics

Grade 7

Full Time Hours

Salary (inclusive of London allowance): £33,353 - £40,313 per annum

Duties and Responsibilities

Applications are invited for the post of Post-Doctoral Research Associate within the Genetics Research Department, UCL Institute of Ophthalmology. The successful applicant will join a strong research team led by Dr Rachael Pearson and Professor Robin Ali, which is examining the potential for retinal repair and regeneration by photoreceptor replacement and has published a number of landmark studies (Pearson et al., Nature 2012; MacLaren & Pearson et al., Nature, 2006; Gonzalez-Cordero et al., Nature Biotech.).

This new project will be to examine the potential for reactivating endogenous repair mechanisms. The applicant will work with murine models of retinal degeneration and will use a variety of molecular and cellular techniques including immunohistochemistry, cell culture, generation and use of viral vectors, RNAi, tissue culture, confocal microscopy, and all standard molecular biology techniques. 

Specifically the post-holder will be required to: have input into project direction and experimental design; work collaboratively with other members of the team; organise the data of the project and maintain a laboratory journal; participate in laboratory meetings and journal clubs; achieve goals, agreed in discussions with the principal investigators, independently and efficiently; present the results of the project in national and international meetings and prepare the results of the project for publication.

The position is funded until December 2016 in the first instance. 

Key Requirements 

The successful applicant will have a good degree (2:1 or higher) and PhD in a relevant subject area, such as neuroregeneration or developmental biology. They will have experience of cell culture, good molecular biology knowledge and experience in confocal microscopy. Experience of working with stem cells, development and/or regeneration would be advantageous. The applicant will also have evidence of completed research, as well as an appropriate publication record, and be able to demonstrate an ability to generate and develop their own research ideas.

Closing date for applications: 17:00 GMT on 19 January 2015

Click HERE to apply.


Click HERE for graduate opportunities


You can also visit the UCL Graduate Prospectus page for further opportunities both here and elsewhere at UCL: http://www.ucl.ac.uk/prospective-students/graduate.

Current opportunities:

There are currently no specific opportunities being advertised here.

We also accept speculative enquiries from researchers and students who have been awarded their own funding. Please contact Heather Kneale at mol.therapy@ucl.ac.uk with details of your funding and research interests for further information.

Page last modified on 04 dec 14 14:42