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    • Current clinical trials of gene and cell therapy for sight loss
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News

Photoreceptor transplants restore vision in mice

Europe's first safety trial investigating the transplantation of stem cell-derived retinal cells in Stargardt disease

Key achievements

The world's first eye gene therapy trial - JWB Bainbridge et al. N Engl J Med. 2008

Cell therapy repairs the retina - Pearson RA et al Nature 2012

The first proof-of-concept in eye gene therapy - RR Ali et al. Nat. Genet. 2000

Our latest blog posts

It’s OK to ask about clinical research – an NIHR campaign

‘Defining future eye research’ – a chance for you to help tackle slight loss

  • EyeTherapy blog

Donate here

We are currently conducting two ground-breaking clinical trials:

  • The world's first gene therapy trial in the eye, testing the safety and efficacy of delivering the RPE65 gene to patients with Leber congenital amaurosis (LCA).
  • Europe's first trial testing the safety of transplanting stem cell-derived retinal cells into the eyes of patients with Stargardt disease.

We also have a wide-ranging research programme dedicated to developing novel gene and cell therapies for many forms of sight loss, including:

  • inherited sight loss
  • age-related macular degeneration (AMD)
  • diabetic eye disease
  • uveitis and
  • corneal disease

If you would like to contribute to our research programme, please visit our JustGiving page


Should you wish to discuss your donation, or set up regular monthly payments to support our work, please email eye.info@ucl.ac.uk or call 0207 608 7982 for advice

Who has funded our work

We are grateful to the following funding bodies, charities and companies for their generous support:

The Gene Team appeal, by RP Fighting Blindness (formerly British Retinitis Pigmentosa Society (BRPS))
http://thegeneteam.org.uk/

Foundation Fighting Blindness (USA)
www.blindness.org

TFC Frost Charitable Trust
http://www.justgiving.com/frostfoundation

European Union
http://cordis.europa.eu/home_en.html

Fighting Blindness Ireland
http://www.fightingblindness.ie/

Medical Research Council (MRC)
www.mrc.ac.uk

The Wellcome Trust
www.wellcome.ac.uk

Clingene
www.clinigene.eu/

RP Fighting Blindness (formerly British Retinitis Pigmentosa Society (BRPS))
http://www.rpfightingblindness.org.uk/

Fight for Sight
www.fightforsight.org.uk

The Royal Society
www.royalsoc.ac.uk

National Institute for Health Research
www.nihr.ac.uk/Pages/default.aspx

The Newman Foundation

Special Trustees of Moorfields
http://www.charityperformance.com/charity-details.php?id=12843

Moorfields Eye Charity
http://www.moorfields.nhs.uk/Getinvolved/MoorfieldsEyeCharity

Biotechnology and Biological Sciences Research Council (BBSRC)
http://www.bbsrc.ac.uk/home/home.aspx

We have also received funding from these organisations in the past.

Page last modified on 10 dec 12 16:55


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