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UCL Queen Square Institute of Neurology

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Seminar series

Synaptopathies Seminar Series

Venue (unless otherwise specified): Gilliatt Lecture Theatre, Ground Floor, Queen Square House, UCL Queen Square Institute of Neurology.

Further information:

Steven Devenish; s.devenish@ucl.ac.uk

Previous events:

Please see also photos on the SYNAPS Study Group website

  • Thursday 20th February, 16:00: Dr Tim Viney, Department of Pharmacology, University of Oxford. “Synaptic circuit mechanisms underlying spatial memory and tauopathy”
  • Thursday January 30th 3:30pm: Dr Anna Hoerder-Suabedissen, Department of Physiology, Anatomy and Genetics, University of Oxford. "SNAP25 conditional knockout in cortical layer 5 neurons impairs late but not early circuit formation"
  • Thursday 21st of November, 4:00 pm  Dr Ede Rancz, Cortical Circuits Laboratory, The Francis Crick Institute: Is seeing believing? What might the cortex do
  • Thursday, November 7th 2019 at 5:00pm: Dr. Matthew Gold, Department of Neuroscience, Physiology and Pharmacology, UCL : “'Integration of calcium and cAMP signals in the postsynaptic AKAP79 signalling complex'”
  • Thursday 3rd of October 2019, 5.10pm : Speaker: Dr. Timothy O’Leary Department of Engineering, University of Cambridge: “Synaptic switch stability: a strange effect of small numbers” 
  • Thursday 18th of July 4pm: Dr Sukhvir Wright, Paediatric, Neurology Birmigham Children’s Hospital and School of Life and Health Sciences, Aston University. "Exciting times ahead - NMDAR and AMPARs in epilepsy models"
  • Thursday 16th May 2019 4:00 pm:  Dr Cian O’Donnell, Faculty of Engineering, University of Bristol http://www.bris.ac.uk/engineering/people/cian-odonnell/index.html  "The rules of synaptic plasticity are stochastic"
  • Thursday 2nd May 2019 4pm: Associate Professor Ed Mann, "Over-expression of GluA2 in hippocampal parvalbumin-expressing interneurons leads to memory interference"
  • Thursday 28th February 2019 at 5pm, Prof. Birgit LissDirector, Institute of Applied Physiology, University of Ulm, Germany: "It's complicated - Calcium channels, dopaminergic neurons, and Parkinson's disease"
  • Thursday 14 February 2019 at 4pm,  Dr Afia. B. Ali, Associate Professor in the UCL School of Pharmacy:  "Mechanistic insights into the synaptic microcircuit imbalance in Alzheimer's disease"
  • Thursday 13th December 2018, 4pm: Dr Ingo Greger, MRC Laboratory of Molecular Biology. Structure and function of the AMPA receptor extracellular region in synaptic transmission”
  • Thursday 22 November 2018, 4pm: Dr Marc Busche, University College London; “What happens with neural circuits in Alzheimer’s disease?”
  • Thursday 11 October 4pm, Prof. Marzia Malcangio , Kings College London "Exosomes containing miR-21 mediate nociceptive neuron-macrophage communication after nerve injury"

  • Thursday 27 September 2018, 4pm: Dr Vincenzo Marra, University of Leicester: “Synaptic vesicle distribution in a model of focal epilepsy"

  • Thursday 6 September 2018, 11.30am: Prof Katalin Toth, Université Laval, Quebec city: “A synapse that can count. Information coding and calcium dynamics at mossy fibre terminals.”
  • Thursday 9 August 2018 4pm:   Prof Alaisdair Gibb, Department of Neuroscience, Physiology &  Pharmacology, UCL: “Memantine block of NMDA receptors containing GluN2B subunits with two ion channel mutations associated with West syndrome”
  • Thursday 14 June 2018  4pm:  Dr. Sila Konur Ultanir:  “Understanding the CDKL5 Deficiency Disorder by chemical genetics”
  • Thursday 17 May 2018  4pm:    Prof Denis Burdakov, The Francis Crick Institute
  • Wednesday 11th April 2018 3pm "Temporal coding-induced synaptic plasticity determines clock-driven sleep quality" Dr Mark Wu, Johns Hopkins
  • Wednesday 7th March 1:00 pm
    Synaptopathies extraordinary talk : Title "TBC" Speaker: Prof Yukiko Goda, Rikken Institute, Japan
  • Thursday 8th March 4:00 pm Speaker: Prof Nigel Emptage, Oxford University
  • Thursday 8th February 4:00 pm. ‘Shaping neuronal connections: the role of neurotransmitter release during development’. Dr Laura Andreae, Kings College London
  • Thursday 18 January 2018 4:00 pm: Dr. Vincenzo De Paola ‘Functional human cortical circuitry assembled in vivo‘.
  • Thursday 24 August 2017 4:00 pm: Prof Kailash Bhatia “Paroxysmal dyskinesias”
  • Thursday 21 September 2017 4:00 pm: Speaker: Dr Marco Brancaccio, Cambridge “Astrocytic- neuronal interplay controls circadian pacemaking in mammals” 
  • Thursday 19 October 2017 5:30 pm: Speaker: Prof Patricia Salinas, University College London, "Synapse degeneration and resilience: what we are learning from Wnt signals at the synapse"
  • Thursday 23 November 2017 4:00 pm: Dr Andrew Macaskill. "Cell type and input specificity in ventral circuitry" Venue: Wolfson lecture theatre, 33 Queen Square 

2019 Annual Synaptopathies Symposium

Friday September 20th 2019

About the symposium

The symposium is funded by a Wellcome Trust Strategic Award entitled "Synaptopathies: genetics, biophysics and circuit mechanisms of paroxysmal neurological disorders".

Location: Basement Lecture Theatre, 33 Queen Square, London, WC1N 3BG

2018 Annual Synaptopathies Symposium

Friday September 14th 2018

About the symposium

The symposium is funded by a Wellcome Trust Strategic Award entitled "Synaptopathies: genetics, biophysics and circuit mechanisms of paroxysmal neurological disorders".

Epilepsy, migraine and related paroxysmal neurological disorders affect over 15% of the population, and account for an enormous burden to the individual and to society. Progress in managing these diseases is slow, with many patients failing to respond to available medication. Understanding the mechanisms will be an essential step, not only towards improved diagnosis, but also towards the development of rational therapies.

*This event is open to principal investigators, postdoctoral researchers and PhD students. A limited number of places will be made available to MSc students.*

Location: Basement Lecture Theatre, 33 Queen Square, London, WC1N 3BG