UCL Institute of Neurology


Archive of IoN NEWS

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Human Brain Project wins major EU funding

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The Human Brain Project has been officially selected as one of the European Commission’s two FET Flagship projects. The new project will unite European efforts to address one of the greatest challenges of modern science: understanding the human brain.

Gene mutation causes familial form of cranio-cervical dystonia

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Researchers from UCL’s Institute of Neurology have identified mutations in the gene ANO3 as the cause of a familial form of cranio-cervical dystonia.  Dystonia itself is a common neurological disorder which results in involuntary muscle spasms and is characterised by severe abnormal postures due to involuntary muscle spasms and affects an estimated 70,000 people in UK. Currently, there are no cures found for this disabling condition. The team of researchers, led by Professor Nick Wood and Professor Kailash Bhatia found six changes throughout the gene that might be linked to cranio-cervical dystonia, which triggers abnormal twisting or tremulous movements affecting the face, neck and arms. Of these six changes, three have shown to segregate with disease in three separate families.  The work was published in December in the American Journal of Human Genetics (Charlesworth et al., 2012). Insights into the causes of rarer, familial forms of the disease may help shed light on the cellular pathways involved in the disease as a whole.  The new ANO3 gene determines a channel that is found in the striatum, a part of the brain concerned with movement. It is hoped that an ion channel might represent a feasible target for the development of new treatments.


Professor Ray Dolan awarded prestigious Klaus Joachim Zülch Prize

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Professor Ray Dolan, Head of the Wellcome Trust Centre for Neuroimaging, UCL Institute of Neurology, has been awarded the prestigious Klaus Joachim Zülch Prize.
The K-J. Zülch Prize of the Gertrud Reemtsma Foundation has been awarded for outstanding achievements in basic neurological research every year since 1990. The prize is endowed with 50,000 Euro and has always been awarded and shared by two scientists. The 2013 prize has been awarded to Professor Dolan, and Professor Wolfram Schultz, University of Cambridge (UK). It will be awarded at a ceremony in the historic Cologne town hall on September 13th, 2013. 

Professor Dimitri Kullmann elected Editor of Brain

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Professor Dimitri Kullmann recipient of award recognising outsanding researchers.

Professor Dimitri Kullmann, based in the Department for Clinical and Experimental Epilepsy, at the UCL Institute of Neurology, has been elected as the new Editor of Brain. This neurology journal provides researchers and clinicians with the finest original contributions in the field. Professor Kullmann’s appointment is excellent news for the Institute, and reflects his standing in the academic neurology community.


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