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Research into genetic influences on epilepsy and migraines

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Researchers at UCL Institute of Neurology have begun to investigate genetic influences on neurological disorders such as ataxia, epilepsy and rare and severe headache disorders.

Fast forwarding treatment for neurodegenerative disorders at LWENC

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Leonard Wolfson clinical trials day

The Leonard Wolfson Experimental Neurology Centre (LWENC) was established through a £20 million award from the Wolfson Foundation to UCL in 2011 and is based at the National Hospital for Neurology and Neurosurgery (the partner hospital of the UCL Institute of Neurology). It is the first centre the UK dedicated to fast-forwarding progress towards effective treatments for neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and prion disease.

Natural genetic variation gives complete resistance in prion diseases

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Prion protein expressed in E. coli

Researchers at the Medical Research Council’s Prion Unit at the UCL Institute of Neurology have identified a naturally occurring variant of the human prion protein that produces resistance to prion diseases such as Creutzfeldt-Jakob disease (CJD). The findings, published in Nature, could give important insight into other human brain diseases that lead to dementia.

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