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Dr. Janice Holton, Honorary Consultant and Reader in Neuropathology
Dr Holton participates in the routine work of the Division of Neuropathology reporting neurosurgical specimens as part of a team of 6 Consultant Neuropathologists and has responsibility for the adult muscle biopsy diagnostic service.
Adult muscle biopsy service
The Division of Neuropathology receives 180-200 muscle biopsies annually from adult patients and Dr Holton is the lead Neuropathologist for the service which provides a routine diagnostic service and supports the mitochondrial disease and the McArdle’s disease NCG services based in the National Hospital for Neurology and Neurosurgery. All cases are discussed with consultant neurologist colleagues at the weekly multidisciplinary team meeting and a record of the discussion is made available on the electronic patient record.
Dr Holton is actively engaged in research in the field of inflammatory muscle diseases and has recently written a book chapter on the subject. She is a founder member of the Council of the British Myology Society.
Queen Square Brain Bank
The Queen Square Brain Bank (QSBB) houses one of the largest neurodegenerative brain tissue resources in the UK. This unique collection consists of cases of Parkinson’s disease, hereditary forms of parkinsonism and cases presenting with an atypical parkinsonian syndrome such as progressive supranuclear palsy, corticobasal degeneration and multiple system atrophy. Since 2002 a prospective collection of brain tissue from well-documented early onset and familial dementia cases has been added to the portfolio. Approximately 90 cases are received each year and all are subject to an extensive diagnostic process and a full report is issued by either Dr Holton or Professor Revesz. Following this, cases are made available to researchers for study. Dr Holton is actively involved in neuropathological research in the fields of multiple system atrophy, Parkinson’s disease and dystonia.
Dr Holton is an active member of the British Neuropathological Society and has held the offices of Treasurer and Chair of the Education and Meetings Committee. In the latter role she was responsible for the organization of the annual meeting of the Society including the preparation of the scientific programme. She also organized two summer schools on behalf of the Society.
Dr Holton has been a member of the editorial board of Neuropathology and Applied Neurobiology, the journal of the British Neuropathological Society since 2006 and has acted as an Executive Editor since January 2012.
Page last modified on 03 may 12 10:54