Professor Tarek Yousry
The Unit’s research focuses on anatomic, functional and vascular imaging.
Professor Xavier Golay
My research interests lie at the intersection of many disciplines, such as MRI physics, chemistry, physiology and neuroscience. They include the development of MRI as a translational tool for neurological diseases.
collaboration with Professor Roger Ordidge (Head of the Wellcome Trust
High-Field MR Laboratory), we are developing a programme to advance
morphological imaging using high resolution imaging (3T MR) and MR
microscopy (7T). This will enable us to advance our understanding of
the pathogenesis of diseases such as MS, Alzheimer’s disease and
hippocampal sclerosis; to improve the accuracy of therapeutic
interventions in functional neurosurgery; and to improve the
specificity of quantitative MR. In collaboration with the Stroke Unit,
we are developing and using MR specific techniques that will assist us
in advancing our understanding
of pathological mechanisms leading to stroke. In collaboration with the Wellcome Department of Imaging Neuroscience, we are introducing functional imaging into the clinical environment and are therefore in the process of establishing the indications for the clinical use of fMRI.
Finally, in collaboration with Dr Jeremy Rees (Department of Molecular Neuroscience), we are determining early markers of transformation of lowgrade gliomas into high-grade gliomas using diffusion and perfusion imaging. Dr Klaus Schmierer, in collaboration with Professors Tarek Yousry, Sebastian Brandner (Department of Neurodegenerative Disease), David Miller (Department of Neuroinflammation) and Roger Ordidge (Department of Medical Physics, UCL), is investigating the potential of using high field strength MRI and quantitative histology into postmortem examination of brains from patients with MS. The activities of the Unit will increase significantly with the completion of the “Joint MR Project” during 2006, to provide an additional .5T MR, 3T MR, and an interventional MR suite within the NHNN.