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UCL Institute of Neurology

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Cognitive Neurology

Five clusters of voxels survive a whole brain correction for multiple comparisons. Peak positive and negative clusters are displayed in axial slices*

Investigating how cognitive processes (thinking, memory and language skills) are damaged by acquired brain injury and how to restore or compensate for their loss.

Lead:

Professor Alex Leff

Research Team

Research Goals

  • To develop novel, evidence-based therapies for patients with cognitive impairment and to investigate how, at a neural network level, these therapies work.
  • To identify key brain and behaviour markers that will allow us to make individualized predictions of: i) recovery from brain injury; ii) response to therapies for brain injury
  • See also http://www.ucl.ac.uk/aphasialab/

Funded Research Projects

  • Digital neuro-interventions to enhance re-learning in patients with acquired and degenerative brain diseases. Developing three separate digital neuro-interventions for: (1) patients with visuospatial neglect; (2) patients with dementia who forget familiar names; (3) aphasic patients who have word-finding difficulties. Funded by an NIHR (National Institute for Health Research) Research Professorship.
  • The ‘Listen-In’ project: developing, testing and rolling-out at a web-based therapy application for patients with impaired speech comprehension caused by stroke. Funded by the NIHR i4i programme.
  • The Read-Right and Eye-Search projects are for patients with hemianopia that causes, respectively, a reading problem and a problem with visual search. Both therapies work by retraining eye movements, to make them more efficient. Funded by the Stroke Association and NIHR.
  • Back of the brain project: a cross-sectional study with a new approach to cerebral localisation of visual perceptual functions. Funded by the Danish Research Council.
Recent publications from Cognitive Neurology

Further information

 *  Hope et al. Right hemisphere structural adaptation and changing language    skills years after left hemisphere stroke. Brain 2017; 140(6):1718-1728 10.1093/brain/awx086