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Professor Nick Fox wins 2017 Weston Brain Institute International Outstanding Achievement Award Winner

Congratulations to Professor Nick Fox, winner of the 2017 Weston Brain Institute International Outstanding Achievement Award. This £25,000 award recognizes an exceptional investigator who has made significant advances in accelerating the development of therapeutics for neurodegenerative diseases of aging through translational research, demonstrated remarkable leadership, and has a record of impeccable citizenship in the research community. This year’s prize was provided by the Selfridges Group, and was open to researchers working in the UK.

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Genetic modifier for Huntington’s disease progression identified

A team led by UCL and Cardiff University researchers has developed a novel measure of disease progression for Huntington’s disease, which enabled them to identify a genetic modifier associated with how rapidly the disease progresses.

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New Chief Operating Officer takes the helm at UK DRI

Bringing a wealth of experience and innovation in neurodegenerative diseases research, Dr Ivinson is currently Executive Director of the Institute for the Neurosciences, and of the Ann Romney Center for Neurologic Diseases, both at Brigham and Women’s Hospital, a Harvard Medical School affiliate.

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Dr Ed Wild invited to meet Pope Francis at the Vatican on May 18th

Dr Ed Wild of the UCL Huntington’s Disease Centre (UCL Institute of Neurology) has been invited by Pope Francis to attend the Vatican on Thursday 18th May as part of HDdennomore, an event highlighting the plight of Huntington’s disease (HD) sufferers around the world. Dr Wild received the invitation in recognition of his research, clinical care and public engagement into HD; as one of a few specially selected guests, he will also get the chance to meet the Pope in person.

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Professor Martin Rossor awarded ABN medal 2017

We are pleased to announce that Professor Martin Rossor, NIHR National Director for Dementia Research, Director of the Queen Square Dementia Biomedical Research Unit, Professor of Clinical Neurology at UCL Institute of Neurology and Consultant Neurologist at the National Hospital for Neurology and Neurosurgery, is the ABN Medallist 2017.

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The UCL Huntington’s Disease Centre opens

We are delighted to announce that the UCL Huntington’s Disease Centre, UCL Institute of Neurology, was officially opened on 1 March by UCL President and Provost Professor Michael Arthur.

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Iceland delivers on £10m pledge to UCL Dementia Research

Iceland Foods Charitable Foundation has today made an initial donation of £3 million to support the development of the hub of the UK Dementia Research Institute at UCL, the go-ahead for which was announced in December. This is the first tranche of a total of £10 million pledged to the project by Iceland, to be raised through the sale of 5p single-use carrier bags in Iceland stores across the UK and through the fundraising efforts of Iceland’s people, customers and suppliers.

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UCL’s innovative retail coalition celebrates first anniversary

UCL is today marking one year since the launch of the innovative retail coalition inspired by Malcolm Walker of Iceland Foods to address the dementia challenge. Since the coalition was created nine UK retailers have committed to support UCL in its fight against dementia, initially pledging in the region of £20 million. In the first year alone, the partnership has already raised around £10 million – equivalent to the sale of around 200 million carrier bags.

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Trial shows signs new Alzheimer's drug could benefit early-stage patients

Dr Cath Mummery, head of clinical trials at the Dementia Research Centre, UCL Institute of Neurology, was interviewed on BBC News and Channel 4 yesterday evening about the interim results of a Phase I study of adecanumab, a monoclonal antibody, reported in Nature.

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UCL success at Dementia Research Leaders awards

We are delighted to announce the success of UCL Institute of Neurology researchers at the Alzheimer's Society Dementia Research Leaders awards, which were presented at the Alzheimer's Society Research conference on June 30th 2016.

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How Huntington’s could help unlock the challenges of dementia

Professor Sarah Tabrizi, Director of the Huntington’s Disease Centre, UCL Institute of Neurology, gave an inspiring keynote speech at Google’s Zeitgeist. Zeitgeist is a high-profile gathering of business leaders and thinkers. Professor Tabrizi’s speech focused on how research on a genetic dementia like Huntington’s disease may not only offer hope to those who carry the Huntington's gene but also unlock treatments for other more complex dementias such as Alzheimer’s disease.

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Exploration of dementia announced as second project of The Hub at Wellcome Collection

A group exploring dementia and the arts have been invited to take up the 2016-2018 residency in The Hub at Wellcome Collection, a flagship space and resource for interdisciplinary projects exploring health and wellbeing. Bringing together a rich network including scientists, artists, clinicians, public health experts and broadcasters, the group will examine and challenge perceptions of dementia through scientific and creative experimentation. They have been awarded £1 million to develop the project over two years.

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Major Wellcome Trust award to UCL boosts Huntington’s disease research

UCL today announced that a team of researchers from UCL and the University of Cambridge led by Professor Sarah Tabrizi, Director of the Huntington’s Disease Centre, UCL Institute of Neurology, have been granted a prestigious Wellcome Trust Collaborative Award in one of the largest investments in Huntington’s Disease (HD) ever given by a public funding body in the UK. The 5-year, £3.4 million investment will support research to help our understanding of disease mechanisms in HD and, importantly, their response to treatment. This valuable work will in turn provide insights into other more common neurodegenerative diseases.

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UCL launches free online dementia course

UCL Institute of Neurology has today announced a free four-week online course “The Many Faces of Dementia” aiming to provide valuable insights into dementia through the stories, symptoms and science behind four less common diagnoses. The interactive MOOC (massive open online course) features interviews with world-leading experts, people with dementia and their families as well as articles and discussion.

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UCL Institute of Neurology hosts inaugural Ada Lovelace Day event

The UCL Institute of Neurology invited a group of teenage girls from Camden’s Parliament Hill School to visit on 13 October as part of an initiative to encourage more to pursue studies in science, technology, engineering and mathematics (STEM).

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First human trial for innovative new drug in development to treat Huntington’s disease

Patients in London are being dosed for the first time with an experimental drug for Huntington’s disease. This breakthrough could be one of the most important developments since the gene for Huntington’s disease was discovered in 1993. The trial of the revolutionary new ‘gene silencing’ treatment is being led by scientists at UCL’s Institute of Neurology. The first patients received doses of the drug at the Leonard Wolfson Experimental Neurology Centre at UCLH's National Hospital for Neurology and Neurosurgery.

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UCL and UK supermarkets unite to beat dementia

UK supermarkets Iceland, Asda, Morrisons and Waitrose have today pledged funds from the new levy on single-use carrier bags to support the construction of a new world class dementia research centre at UCL.

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Possible evidence for human transmission of Alzheimer’s pathology

Amyloid beta pathology in the grey matter and blood vessel walls characteristic of Alzheimer’s disease (AD) and the related cerebral amyloid angiopathy (CAA) is observed in the brains of deceased patients who acquired Creutzfeldt–Jakob disease (CJD) following treatment with prion-contaminated human growth hormone.

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Compensation in Huntington’s disease

A new measure has been developed which can explicitly characterise compensation in Huntington’s disease (HD) gene-carriers prior to clinical diagnosis. Publishing in EBioMedicine, the research team working on the study hope that identifying patterns of compensation in preclinical HD will not only improve understanding of neural mechanisms underlying HD pathology, but also provide potential targets that can be used in the testing of HD therapeutics.

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