PAPER - PD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8+ T cells

17 August 2011

Centre members Dr David Escors and Prof Mary Collins show that the interaction between programmed cell death 1 ligand 1 (PD-L1) on dendritic cells (DCs) and programmed death 1 (PD-1) on CD8 T cells contributes to ligand-induced TCR down-modulation.  Full details can be found at the EMBO Molecular Medicine website.

Page last modified on 17 aug 11 10:36