The League of Gentlemen reassembled in a World AIDS Day fund-raiser for the Institute at the Adelphi Theatre, London.
Immunity and infection project wins Times Higher Education International Collaboration of the Year award
A UCL research and
training project centered on a diagnostic test for tuberculosis (TB) has won the
Times Higher Education (THE) International Collaboration of the Year award.
Examples of clinical trials taking place via the Institute of Immunity and Transplantation:
Current and planned studies:
Transplantation and infection: A randomised, placebo-controlled comparison of two monoclonal
antibodies given in combination to cytomegalovirus-negative transplant
patients receiving a kidney from a positive donor. This will be a multinational, multicentre trial of the "Royal
Free Protocol" of pre-emptive therapy to prevent cytomegalovirus transmission during kidney transplantation. Chief investigator: Paul Griffiths.
Chronic infection in children: A double-blind randomised placebo-controlled trial to test whether anti-viral treatment improves outcomes for babies who have sensorineural hearing loss caused by congenital cytomegalovirus infection. Chief investigator: Paul Griffiths.
Cancer and transplantation: Multicentre, phase II randomized study of prophylactic transfer of donor CD4 cells following HLA-identical sibling transplantation for haematological cancers (ProT4): This study is testing the efficacy of prophylactic transfer of CD4 cells in reducing the risk of blood/lymphatic cancer relapse following allogeneic blood or marrow stem cell transplantation. Selection of CD4 cells can be achieved easily by most stem cell processing labs. Thus, if efficacy can be proven, this approach could be easily applied across most transplant centres. Chief investigator: Ronjon Chakraverty.
Recently completed studies:
Transplantation and infection: This phase II trial of cytomegalovirus glycoprotein B vaccine was funded by the US National Institutes of Health and published in the Lancet in 2011. It has kickstarted several programs to try to protect transplant patients from disease by preventing transmission of cytomegalovirus from the donor using the "Royal Free Protocol" of pre-emptive therapy. Chief investigator: Paul Griffiths.
Transplantation and infection: This randomised controlled trial investigated when to start and when to stop pre-emptive therapy to protent transmission of cytomegalovirus from transplant donors to recipients, as part of a wider Wellcome Trust funded research programme. Chief investigator: Paul Griffiths.
Page last modified on 17 dec 12 15:14