DTP Supervisors
Prof. Daniel Alexander
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UCL Centre for Medical Image Computing
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Daniel
Alexander leads the Microstructure Imaging Group. The groups research
interests include active imaging and diffusion MRI.Our active imaging
approach centres on the active imaging paradigm. The paradigm treats the
problem of estimating features of tissue microstructure from
measurements made with an imaging device as a classical estimation
problem.
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email - website
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Expertise: Diffusion Imaging
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Dr David Atkinson
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UCL Centre for Medical Imaging
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From
a background in semiconductor optical modulators and optical fibre
systems, in 1996 I moved into medical imaging, specifically to address
the problem of motion correction in Magnetic Resonance Images. I am
still active in this field and also in fast MR imaging of blood flow,
high resolution diffusion weighted imaging, image registration in the
presence of contrast changes and rapid MR image reconstruction and
acquisition.
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email - website
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Expertise:
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Dr Dean Barratt
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UCL Centre for Medical Image Computing
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Dean
focuses on developing deformable registration techniques for
aligning diagnostic-quality MR images of the prostate to transrectal
ultrasound (TRUS) images obtained during ablative interventions and
needle biopsy procedures. The aim of this research is to provide
high-accuracy surgical guidance technology to enable MR-targeted biopsy
and minimally-invasive treatments for prostate cancer. The group has
developed an automatic registration technique for this purpose which
combines biomechanical tissue modelling and stastical techniques. Other
areas of research activity include multifunctional MR imaging of
prostate cancer, automatic segmentation of MR images, and computer
simulation of biopsy protocols to maximise tumour detection and
localisation accuracy.
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email - website
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Expertise:Ultrasound, image-guided surgery, prostate cancer
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Prof. Paul Beard
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UCL Dept. of Medical Physics and Bioengineering
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Paul Beard leads the Photoacoustic
Imaging Group in the Departmental of Medical Physics and Bioengineering. The
group was one of the early pioneers of photoacoustic imaging and has since
grown to be one of the largest worldwide. It has a strong international
reputation having been responsible for many significant developments in
photoacoustic imaging instrumention and image reconstruction methods. The group
is highly multidisciplinary and its members have a diverse range of backgrounds
(optical physics, electronic engineering, acoustics, mathematics, microwave
engineering, chemistry, computer science) allowing it to encompasses the
full range of activities in photoacoustic methods: modelling optical and
acoustic propagation in tissue, image reconstruction methods, detection and
excitation instrumentation, spectroscopic methods, molecular imaging and
clinical and preclinical imaging studies in cancer and cardiovascular disease.
Projects in all of these areas are available and informal enquiries from
students looking for either an MRes or PhD project are welcomed.
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email - website
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Expertise:
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Dr Chris Clark
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UCL Institute of Child Health
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Chris's research focus is on the development and application of diffusion tensor imaging (DTI) and tractography for the understanding of neurological disability. Tractography uniquely allows the mapping of the white matter tracts of the living human brain. These methods can be used to reconstruct a wide range of clinically eloquent tracts such as the cortico-spinal tracts, fornix, optic radiations and uncinate fasciculus among others. A particular theme of research in which he has been active is the development of these methods for the purposes of neurosurgical planning in both children and adults. I am also using these methods to investigate the relationship between white matter damage and post-surgical deficits.
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email - website
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Expertise:
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Dr Ben Cox
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UCL Dept. of Medical Physics and Bioengineering
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Ben's research has
focussed principally on acoustics, especially efficient tissue-realistic
models for simulating photoacoustic and ultrasonic wave propagation using
spectral methods (which led to the widely used k-Wave Matlab Toolbox). He
also works on inverse problems (including imaging) in acoustics and biomedical
optics, as well as diagnostic and therapeutic ultrasound.
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email - website
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Expertise:
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Dr Anna David
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UCL Institute for Women's
Health
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Dr
David obtained a PhD on clinically applicable methods of delivering
fetal gene therapy in 2005 at UCL and the group was established in 2007.
The unifying aim of the research is to develop prenatal treatment of
severe and life-threatening disorders using gene and cellular therapy,
and to investigate the efficacy, safety and ethical issues of such
treatment. This work is internationally competitive and only a few
groups in the world are working in the area.
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email - website
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Expertise:
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Dr Michael Duchen
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UCL Centre for Neuromuscular Disease
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Michael
is interested in a wide range of issues related to mitochondrial
biology and cell signaling. Much of our current work is focused on
interrelationships between calcium signaling, mitochondria and free
radicals in cell physiology and pathophysiology. This work embraces
questions about the contributions of mitochondrial function to
intracellular calcium signaling; about the contributions of
mitochondrial dysfunction to cell injury and cell death in situations
such as ischaemia, reperfusion injury; in diseases associated with
mitochondrial mutations, in the major neurodegenerative disease and in
muscular dystrophies. It also encompasses questions about the
contributions of mitochondrial function to the propagation of intra- and
intercellular calcium signals.
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email - website
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Expertise:
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Dr Adam Gibson
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UCL Dept. of Medical Physics and Bioengineering
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I am interested in multi-modality imaging, particularly combining diffuse optical imaging with other imaging modalities (especially MRI, x-ray, EEG). How can we extract biological parameters of clinical interest from combined imaging? Can we combine the images with patient or other clinical data to aid interpretation?
I'm also interested in image-guided radiotherapy. How can we best target a beam of x-rays or protons onto a tumour in order to cure the cancer while sparing healthy tissue? Again, can we derive biological
parameters of interest so we specify the treatment in terms of biological cure rather than physical dose distribution?
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email - website
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Expertise:
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Dr Alexander Gourine
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Alexander
is a Wellcome Trust Senior Research Fellow at University College
London. He gained his PhD at the Russian Academy of Medical Sciences
(Moscow, Russia), received postdoctoral training in the US and the UK
and was appointed to the Department of Physiology as The Wellcome Trust
Senior Fellow in 2006. He was awarded the Physiological Society’s
Wellcome Trust Prize in the year 2004 for his contribution to
understanding the mechanisms underlying chemosensory control of
breathing.
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email - website
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Expertise:
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Professor Xavier Golay
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UCL Institute of Neurology
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Xavier is a Professor of Neurophysics and Translational
Neuroscience at the UCL Institute of Neurology. He received his Ph.D.
on Functional MRI at the Swiss Federal Institute of Technology of
Zurich (ETHZ), where he worked as a research assistant in the group of
Professor Peter Boesiger. His research interests include the
development of MRI as a translational tool for neurological diseases, aiming
at measuring identical image-based biomarkers from mouse to human,
and from the laboratory to the clinical settings. Xavier has
served on many committees of the ISMRM and ESMRMB including on the
Board of Trustees, he is author on more than 90 journal articles and a
member of the Editorial Board of NMR in Biomedicine and Magnetic
Resonance Materials in Physics Biology and Medicine.
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email - website
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Expertise:
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Prof. David Hawkes
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UCL Centre for Medical Image Computing
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Dave
Hawkes is currently the Director of the Centre for Medical Image
Computing, previously having been Director of the EPSRC and MRC funded
Interdisciplinary Research Collaboration on Medical Images and Signals
(MIAS-IRC), an £8M six year programme, from 2003 to 2007 and Chairman of
the Division of Imaging Sciences at KCL (2002-2004). He spent 10 years
working as a clinical scientist within the NHS before returning to
academia. He is co-Founder of IXICO Ltd. (www.ixico.com), a university
spin-out that provides imaging solutions to the pharmaceutical industry.
His current research interests encompass image matching, data fusion,
visualisation, shape representation, surface geometry and modelling
tissue deformation promoting medical imaging as an accurate measurement
tool and image guided interventions.
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email - website
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Expertise:
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Prof. Jem Hebden
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UCL
Biomedical Optics Research Laboratory
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Jem Hebden is
currently Director of the Biomedical Optics Research Laboratory (BORL) and Head
of the UCL Department of Medical Physics & Bioengineering. BORL is Europe’s
largest research facility devoted to biomedical optics, and has pioneered the
development of optical instruments and techniques for imaging and monitoring
biological tissue. Jem’s group has developed various novel imaging systems for diffuse
optical tomography of the brain and female breast. The group has produced the first
whole-brain images of evoked functional activity in the newborn infant, and this
work is currently focussed on the study of hypoxic-ischemic brain injury and
infant seizures. In addition, systems have been built for mapping the
haemodynamic response in the cortex to sensory stimulation and other cognitive
activity in adults, children, and babies, and to acquire EEG measurements
simultaneously.
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email - website
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Expertise:
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Prof. David Holder
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UCL Dept. of Medical Physics and Bioengineering
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David
has been Consultant in Clinical Neurophysiology at UCH since 1997 where
I undertake EEG reporting, nerve conduction studies and EMG
(electromyography). I have an interest in the development of new methods
for diagnosis, such as vibration studies for RSI (repetitive strain
injury), ambulatory nerve conduction studies for functional nerve
entrapments which cause pain on exercise, and using machine learning
methods for automated analysis of the EEG.
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email - website
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Expertise:
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Prof. Brian Hutton
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UCL Institute of Nuclear Medicine
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Brian
joined the Dept of Nuclear Medicine at Royal Prince Alfred Hospital,
Sydney in 1975 and headed the Physics group from 1981-1995. He played a
central role in the establishment of the National PET Facility at RPA
Hospital and in 1990 was attached to the MRC Cyclotron Unit at
Hammersmith Hospital, London. He later held an appointment as Head of
the Diagnostic Physics Group at Westmead Hospital, Sydney where his
research interests included SPECT quantification, image reconstruction
and multi-modality imaging problems. He also accepted a part-time
Professorial appointment at the University of Wollongong. In addition he
has acted as project manager for a major initiative in technologist
education originally developed for use in the Asian region, but now also
in use in Africa and Latin America (IAEA funded). He currently directs
research in nuclear medicine physics which includes development of
reconstruction algorithms, design and evaluation of novel tomographic
systems and corrections for effects of motion and partial volume
effects.
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email - website
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Expertise:
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Prof Louis Lemieux
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UCL Institute of Neurology
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Investigation
of the generators and networks of epileptiform activity using
multi-modal functional imaging; study of the relationship between brain
morphological changes and disease progression using serial MR image
quantification; integration and evaluation of multi-modal imaging and
electrophysiological data for surgery planning in Epilepsy; multi-modal
neurophysiological data fusion modelling; investigation of safety in
relation to MR and brain implants.
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email - website
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Expertise:
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Dr Terence Leung
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UCL Department of Medical Physics and Bioengineering
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Terence
is an EPSRC Career Acceleration Fellow and leads the UCL Acousto-optics Group. The
aim of the group is to investigate the interaction between sound and light in a
diffuse medium, and its application in biomedical problems. Acousto-optic
techniques can provide information about both the optical (e.g. colour) and
acoustic (e.g. stiffness) properties of the medium. Current problems under
investigation include acousto-optic imaging of tissue structure (e.g. breast),
acousto-optic monitoring of High Intensity Focused Ultrasound lesion formation,
and estimation of venous oxygen saturation with microbubbles. Terence’s other
research interests include diffuse optics, physiology measurements, biomedical
signal processing and teaching aid development.
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email - website
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Expertise:
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Dr Mark Lythgoe
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UCL Centre for Biomedical Imaging
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Mark is Director of the Centre for Advanced Biomedical Imaging, which is
a new multidisciplinary research centre for experimental imaging. Mark
is a neuroscientist and uses Magnetic Resonance Imaging (MRI) techniques
for investigating brain and cardiac function. During his time at
University College London (UCL), Mark has established the first
preclinical imaging centre and has been awarded £14m in grants for the
development of an imaging strategy across the university.
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email - website
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Expertise:
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Dr Alessandro Olivo
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UCL Dept. of Medical Physics and Bioengineering
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My group is active in the area of phase-based x-ray imaging methods, based around, but not limited to, the methods I invented (edge-illumination and coded-aperture phase contrast imaging). We are currently lookinginto:
a) the implementation of the coded-aperture method (in 2 and 3D) into new areas of application in medicine and elsewhere;
b) the development of quantitative phase and "dark-field" methods for precise material/tissue identification and characterization;
c) the development of new, "phase-based" contrast agents;
d) the development of new "ultra-sensitive" phase methods at synchrotrons;
e) strategies to reduce radiation dose delivery based on the use of elastic x-ray processes;
f) the extension of the above methodologies to other types of radiation.
Related areas of research currently under investigation are in radiation detectors development and characterization, image processing and analysis.
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email - website
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Expertise:
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Dr Sebastien Ourselin
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UCL Centre for Medical Image Computing
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Sebastien is the Deputy Director of the Centre for Medical
Image Computing (CMIC) and Reader in Medical Image Computing. He
obtained his PhD in Computer Science from INRIA (France) in the field
of medical image analysis under the supervision of Prof. Nicholas
Ayache. He has published over 140 journal and conference articles. He
is an associate editor of IEEE Transactions on Medical Imaging and a
member of the Editorial Board of Medical Image Analysis.
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email - website
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Expertise:
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Prof. Barbara Pedley
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UCL Cancer Institute
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Barbara's
group develops, tests and optimises selective cancer treatments in
vitro and in vivo, using novel antibody and vascular targeted therapies
as either single or combined strategies (Fig 1). We have increasingly
concentrated on the impact of the tumour microenvironment on therapy and
vice versa, and a major part of our research concerns the development
of systems for overcoming or exploiting tumour heterogeneity, in order
to optimise future clinical trials. The most intensively studied tumour
is colorectal carcinoma, but many of the other common tumours are also
under investigation.
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email - website
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Expertise:
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Dr Nikki Robertson
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UCL
Institute for Women’s Health
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Nikki's
research focuses on fundamental mechanisms of perinatal brain injury,
the role of MR techniques to interrogate the neonatal brain and the
development and translation of neuroprotective strategies.
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email - website
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Expertise:
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Dr Gary Royle
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Gary Royle is professor of Medical
Radiation Physics within the department of Medical Physics and Bioengineering
and leads a proton therapy research team. Research interests include the
development of imaging and detection techniques for cancer treatments, namely
proton therapy and advanced radiotherapy. The purpose of the imaging techniques
is for either image guided treatments, treatment verification or to assess the
effectiveness of the cancer treatment. Project areas include development
ofnovel imaging techniques, instrumentation and computer simulation. Projects
are performed in collaboration with clinical colleagues in the radiotherapy
department at UCL hospital. Proton therapy projects are performed in
association with clinical proton therapy centres in the UK
and overseas.
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email - website
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Expertise:
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Dr Nader Saffari
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Nader
Saffari's research interests include ultrasonic characterisation of
biomaterials and advanced engineering materials, modelling of high
intensity focused ultrasound for ablation of tumours, acoustical
imaging, applications of ultrasound in functional tissue engineering,
mathematical modelling of ultrasound propagation and scattering in
inhomogeneous media, characterisation of ultrasound contrast agents for
medical diagnostic and therapeutic applications and ultrasonic
tomography.
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email - website
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Expertise:
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Dr Karin Shmueli
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UCL
Department of Medical Physics and Bioengineering
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Karin is interested in
developing Magnetic Resonance Imaging (MRI)
techniques for clinical applications. Her current research focuses on
understanding and exploiting MRI
frequency contrast. Conventional MRI
uses only the signal magnitude, but utilising the frequency has dramatically
improved visualisation of tissue structure and can reveal tissue composition. During
her previous post at the USA National Institutes of Health, Karin developed new
methods to calculate tissue magnetic susceptibility maps from MRI frequency images – an exciting technique and a
rapidly growing research area. She now aims to unlock the potential of MRI frequency
methods to generate clinical MRI
biomarkers of disease.
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email - website
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Expertise:
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Dr Dan Stoyanov
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UCL Centre for Medical Image Computing
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My research interests are in the development of surgical vision or surgical robot vision for images obtained during minimally invasive surgery and robotic assisted surgery. These involve vision problems related to deformable structure-from-motion, scene flow, recognition and photometric and geometric camera calibration. My research is mostly applied contributing to improvements in surgical treatment for example by allowing advanced image guidance and control in robotic assisted surgery. More recently, I have also started investigating the use of vision technologies to enable in vivo biophotonic imaging modalities and to provide information for objective surgical skill evaluation and analysis.
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email - website
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Expertise:
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Dr Paul Taylor
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UCL Centre for Health Informatics & Multiprofessional Development
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Paul's main research interest is in clinical decision support systems which includes understanding the information needs of clinicians, designing tools to present relevant clinical information and assessing the effectiveness of technology designed to help clinicians make decisions.
The
main focus of my research has been in medical imaging. Two major
projects involved (a) designing and building a system for the
differential diagnosis of mammographic calcifications and (b) assessing
the potential of a commercial system designed to alert radiologists to
potential abnormalties. This research is developing in a new direction
and I am now working on the development of a system to help train
radiologists seeking to specialise in screening mammography. We hope to
extend these ideas to other areas of radiology.
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email - website
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Expertise:
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Dr Claudia Wheeler-Kingshott
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UCL Department of
Neuroinflammation
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Claudia's research interests include
- Quantitative MRI in the Central Nervous System;
- Applications mainly to Multiple Sclerosis and spinal cord injury;
- Applications at 1.5T and 3T;
- Multi-nuclear spectroscopy and imaging.
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email - website
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Expertise:
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Dr Gary Hui Zhang
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Centre for Medical Image Computing
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Gary is Lecturer in Medical Image Computing. His research focuses on diffusion MRI and its application to imaging brain tissue microstructure and mapping brain connectivity. He obtained his PhD in Computer Science from University of Pennsylvania in the field of medical image analysis under the supervision of Prof. James C Gee. He leads the development of DTI-TK, a state-of-the-art open-source software package for analyzing diffusion-tensor imaging data.
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email - website
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Expertise:
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Page last modified on 24 jan 13 17:56
