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CNN news: How long can humans live?

Following her BBC interview Professor Linda Partridge spoke with CNN's Bianca Britton, whose article asks, "how long can humans live?" More...

Published: Oct 6, 2016 3:07:38 PM

Linda Partridge interviewed for BBC News on Vijg Nature Paper

On Wednesday, October 5 2016 IHA Director Professor Linda Partridge was interviewed on the BBC 6 O'Clock News about the recent Nature paper by Jan Vijg. The Nature paper entitled "Evidence for a limit to human lifespan" suggests a maximum upper age limit for humans and Prof Partridge was asked to comment on this.

Published: Oct 6, 2016 11:58:50 AM

Linda Partridge and the IHA feature interview with Time Out London

Professor Linda Partridge was recently interviewed by Time Out London and features in today's issue ('Rad Scientists', Time Out, 20/09/2016). You can read the article via our Facebook site at https://www.facebook.com/UCLInstituteofHealthyAgeing/

Published: Sep 20, 2016 11:43:25 AM

Lazaros Foukas

Foukas Lab Website

dr lazaros foukas

  • Dr
  • Lazaros
  • Foukas
  • Dr Lazaros Foukas
  • Ex: 51612
  • l.foukas@ucl.ac.uk
  • Website
  • https://iris.ucl.ac.uk/iris/extResource/image/01/LFOUK88
  • 2009-04-01
  • 7815
  • London
Joined UCL
  • 2009-04-01

Research Summary

Ageing is a process of gradual decline in the physiological functions of the organism. Amongst other derangements, ageing is associated with dysfunction in carbohydrate and lipid homeostatic regulatory mechanisms. Consequently, middle-aged and old individuals have a higher risk of suffering from metabolic disorders. The rapidly increasing incidence of obesity and type-2 diabetes necessitates the development of novel therapeutic agents to combat these conditions and their numerous debilitating complications.

Cell signalling pathways have been successfully targeted in the therapy of major diseases, such as cancer and inflammation. Signalling pathways that sense nutrient availability and regulate metabolic responses represent potential points of intervention for treatment of metabolic disorders. Key signalling pathways in metabolic regulation are the PI 3-Kinase (PI3K) and Target of Rapamycin (TOR) pathways.

We aim to study the mechanisms by which growth factor and nutrient sensing signalling pathways regulate metabolism and the impact of their perturbation on health in the context of ageing. We use a combination of mammalian genetics, cell based models and pharmacological approaches to identify components of cell signalling pathways which can be targeted in prevention or therapy of age-related diseases.

Research Activities
  • 853
  • Cell signalling
  • 1335
  • age-related disease
  • 1016
  • ageing
  • 1177
  • cancer
  • 1017
  • metabolic regulation
  • 1497
  • obesity
  • 1498
  • type-2 diabetes

Academic Background

  • Award Year
  • 2003
    Doctor of Philosophy
    University College London
  • 1997
    Master of Science
    University of Patras
  • 1995
    University of Patras


Lazaros Foukas obtained a PhD in Biochemistry from University College London. He then
went on to conduct postdoctoral research in Bart Vanhaesebroeck’s lab in the
Ludwig Institute for Cancer Research and then in Barts Cancer Institute, Queen
Mary University of London. He joined the Institute of Healthy Ageing at UCL as
a principal investigator in 2009. His research focuses on the role of
signalling pathways in age related pathologies, such as cancer and metabolic disease.

  • LPART24
  • prof dame linda partridge
  • DGEMS65
  • prof david gems
  • BFKIN15
  • dr brian king
  • MJKIV95
  • prof mika kivimaki
  • MKUMA95
  • prof meena kumari
  • MRDUC42
  • prof michael duchen
  • HPIKH73
  • dr hynek pikhart
  • SJDAW90
  • dr sally dawson

Page last modified on 28 oct 13 16:14