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IHA News

Dr Nazif Alic paper published in Royal Society Proceedings B

Congratulations to Dr Nazif Alic whose paper has been published in the Royal Society's flagship biological research journal Proceedings B.
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Published: Dec 18, 2014 5:19:24 PM

Linda Partridge to speak at Nobel Week Dialogue, Live streaming and Q&A

Join in the digital discussion on ageing with IHA Director Linda Partridge as part of this year's Nobel Week Dialogue on 9th December.  More...

Published: Dec 4, 2014 11:04:44 AM

IHA Director Prof Linda Partridge honoured with BBSRC Excellence Award

IHA Director, Professor Linda Partridge, has been recognised with a BBSRC Anniversary Award for Excellence in Bioscience.

The Biotechnology and Biological Sciences Research Council (BBSRC) has recognised outstanding contributions to bioscience made by four of its research community. As part of BBSRC’s 20th anniversary, the awards demonstrate pride for the UK's world-leading bioscience research base and the impact it has achieved in the last two decades.

The awards will be presented at the Great British Bioscience Festival in November.

Professor Jackie Hunter, BBSRC Chief Executive, said: "Our 20th anniversary year is the perfect time to acknowledge and celebrate the achievements of researchers that BBSRC has supported. These awards highlight outstanding achievements that benefit us all and help to make the UK world-leading in bioscience."

Congratulations Linda!
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Published: Nov 7, 2014 4:31:19 PM

Lazaros Foukas


Foukas Lab Website


dr lazaros foukas

Contacts
  • Dr
  • Lazaros
  • Foukas
  • Dr Lazaros Foukas
  • Ex: 51612
  • l.foukas@ucl.ac.uk
  • Website
  • https://iris.ucl.ac.uk/iris/extResource/image/01/LFOUK88
  • 2009-04-01
Address
  • 7815
  • London
Joined UCL
  • 2009-04-01

Research Summary

Ageing is a process of gradual decline in the physiological functions of the organism. Amongst other derangements, ageing is associated with dysfunction in carbohydrate and lipid homeostatic regulatory mechanisms. Consequently, middle-aged and old individuals have a higher risk of suffering from metabolic disorders. The rapidly increasing incidence of obesity and type-2 diabetes necessitates the development of novel therapeutic agents to combat these conditions and their numerous debilitating complications.



Cell signalling pathways have been successfully targeted in the therapy of major diseases, such as cancer and inflammation. Signalling pathways that sense nutrient availability and regulate metabolic responses represent potential points of intervention for treatment of metabolic disorders. Key signalling pathways in metabolic regulation are the PI 3-Kinase (PI3K) and Target of Rapamycin (TOR) pathways.



We aim to study the mechanisms by which growth factor and nutrient sensing signalling pathways regulate metabolism and the impact of their perturbation on health in the context of ageing. We use a combination of mammalian genetics, cell based models and pharmacological approaches to identify components of cell signalling pathways which can be targeted in prevention or therapy of age-related diseases.

Research Activities
  • 853
  • Cell signalling
  • 1335
  • age-related disease
  • 1016
  • ageing
  • 1177
  • cancer
  • 1017
  • metabolic regulation
  • 1497
  • obesity
  • 1498
  • type-2 diabetes

Academic Background

  • Award Year
    Qualification
     
    Institution
  • 2003
    PhD
    Doctor of Philosophy
    University College London
  • 1997
    MS
    Master of Science
    University of Patras
  • 1995
    Dip.
    Diploma
    University of Patras

Biography

Lazaros Foukas obtained a PhD in Biochemistry from University College London. He then
went on to conduct postdoctoral research in Bart Vanhaesebroeck’s lab in the
Ludwig Institute for Cancer Research and then in Barts Cancer Institute, Queen
Mary University of London. He joined the Institute of Healthy Ageing at UCL as
a principal investigator in 2009. His research focuses on the role of
signalling pathways in age related pathologies, such as cancer and metabolic disease.

Collaborators
  • LPART24
  • prof dame linda partridge
  • DGEMS65
  • prof david gems
  • BFKIN15
  • dr brian king
  • MJKIV95
  • prof mika kivimaki
  • DJPEA06
  • dr daniel pearce
  • MKUMA95
  • prof meena kumari
  • MRDUC42
  • prof michael duchen
  • HPIKH73
  • dr hynek pikhart
  • SJDAW90
  • dr sally dawson
  • RCHAR53
  • dr babis rallis

Page last modified on 28 oct 13 16:14