The ladies of the IHA who this year will be participating in Cancer Research UK's 'Race for Life' successfully held a bake sale on Wednesday and raised an impressive £290 towards their total goal! A huge variety of delicious cakes, generously baked by the team and their friends from the IHA, were snapped up by hungry staff and students alike. Thanks team and well done! If you would like to make a donation to this worthy cause please visit the team's JustGiving page at: http://www.raceforlifesponsorme.org More...
Published: May 10, 2013 10:26:26 AM
We are delighted to announce that the 'Green-Darwin' Green Impact Team has won two Bronze Awards which were presented by the Provost at an Awards Ceremony held last week. The IHA's Giovanna Vinti secured the first award for 'Green-Darwin Labs' and the 'Green Darwin' team won a second.
These fantastic achievements form part of the efforts of the wider UCL community in pressing forward the green agenda. Awards went to teams across UCL for work that included putting up awareness-raising notices and posters encouraging people to switch off lights and equipment when not needed, potentially saving 7,038kg CO2 per year; and likewise to print and photocopy double-sided, potentially saving 108,594kg CO2 and £40,220 on resource costs this year across the institution. More...
Published: Apr 30, 2013 10:37:33 AM
Congratulations to Carolina Soto Palma, an MRes student under the supervision of Dr. Gene Schuster, who has been awarded one of only ten UCL Graduate School bursaries to attend The Times Cheltenham Science Festival. More...
Published: Apr 24, 2013 3:37:38 PM
dr lazaros foukas
- Dr Lazaros Foukas
- Ex: 51612
- Genetics, Evolution & Environment
- Div of Biosciences
Ageing is a process of gradual decline in the physiological functions of the organism. Amongst other derangements, ageing is associated with dysfunction in carbohydrate and lipid homeostatic regulatory mechanisms. Consequently, middle-aged and old individuals have a higher risk of suffering from metabolic disorders. The rapidly increasing incidence of obesity and type-2 diabetes necessitates the development of novel therapeutic agents to combat these conditions and their numerous debilitating complications.
Cell signalling pathways have been successfully targeted in the therapy of major diseases, such as cancer and inflammation. Signalling pathways that sense nutrient availability and regulate metabolic responses represent potential points of intervention for treatment of metabolic disorders. Key signalling pathways in metabolic regulation are the PI 3-Kinase (PI3K) and Target of Rapamycin (TOR) pathways.
We aim to study the mechanisms by which growth factor and nutrient sensing signalling pathways regulate metabolism and the impact of their perturbation on health in the context of ageing. We use a combination of mammalian genetics, cell based models and pharmacological approaches to identify components of cell signalling pathways which can be targeted in prevention or therapy of age-related diseases.
- Cell signalling
- age-related disease
- metabolic regulation
- type-2 diabetes
Developmental defects and rescue from glucose intolerance of a catalytically-inactive novel Ship2 mutant mouse.
Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration
Direct interaction of major histocompatibility complex class II-derived peptides with class Ia phosphoinositide 3-kinase results in dose-dependent stimulatory effects.
2003PhDDoctor of PhilosophyUniversity College London
1997MSMaster of ScienceUniversity of Patras
1995Dip.DiplomaUniversity of Patras
Lazaros Foukas obtained a PhD in Biochemistry from University College London. He then
went on to conduct postdoctoral research in Bart Vanhaesebroeck’s lab in the
Ludwig Institute for Cancer Research and then in Barts Cancer Institute, Queen
Mary University of London. He joined the Institute of Healthy Ageing at UCL as
a principal investigator in 2009. His research focuses on the role of
signalling pathways in age related pathologies, such as cancer and metabolic disease.
- dr emmanouil stamatakis
- prof linda partridge
- prof david gems
- dr eugene schuster
- dr brian king
- prof mika kivimaki
- dr daniel pearce
- dr meena kumari
- prof michael duchen
- dr hynek pikhart
- dr sally dawson
- dr babis rallis
Page last modified on 12 aug 11 11:44