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IHA News

Gems Lab Summer Roundup

Congratulations to Jennifer Tullet (again!)

In September, Dr Jennifer Tullet will cease to be a postdoc, and take up
a Principle Investigator position running her own lab at the University
of Kent, where she will continue her investigations of ageing in C.
elegans. Jennifer also recently spoke at the American Aging Association
meeting in San Antonio, Texas, and recently published a paper entitled
“DAF-16 target identification in C. elegans: past, present and future”
in the journal Biogerontology.

Congratulations to Dr Yila de la Guardia!

Yila de la Guardia recently passed her Ph.D. viva (examiners, Prof Bart
Braeckman from the University of Ghent, and Dr Lazaros Foukas from the
IHA). Yila has now returned to Panama, and she is much missed.

New members of the lab

The lab welcomes three new members! Dr Yuan Zhao moved to the lab from
Cancer Research UK, London, where she worked on telomeres in fission
yeast with Dr Julie Cooper; and Dr Evgeniy Galimov from the National
Research Centre for Preventive Medicine, Moscow, where he worked on ROS
signalling and p66shc with Prof Viktor Skulachev. Both positions are
funded by the Wellcome Trust. Welcome also to Thanet Sornda who recently
started Ph.D. research in the lab. Thanet previously did a Master’s
degree at the Institute of Ageing and Health, Newcastle University, and
is funded by the state of Thailand.

News about David Gems

David gave various talks, e.g. at the Genetics of Aging and Longevity
meeting in Sochi (April), Russia, the British Society for Research on
Ageing meeting in Liverpool (July), and at Oxford and Cambridge
universities. He recently published two essays: 'What is an anti-aging
treatment?' Exp. Gerontol. (2014) 58: 14-18; and 'Evolution of sexually
dimorphic longevity in humans.' Aging (2014) 6: 84-91.
More...

Published: Sep 4, 2014 5:02:16 PM

Congratulations to Adam Dobson

Congratulations to Dr Adam Dobson who has been awarded a grant from the Cornell Center for Comparative and Population Genomics to study how the Drosophila gut changes in response to nutritional manipulations. This will establish a collaboration between the Piper lab and Dr Nicolas Buchon at Cornell University.
More...

Published: Sep 4, 2014 4:58:38 PM

Science Paper published

A recent Science article published by a team of UCL researchers including the IHA's Dr Teresa Niccoli sheds light into toxicity mechanisms. View the article here: http://goo.gl/2sgNCb More...

Published: Aug 19, 2014 10:24:04 AM


dr daniel pearce

Contacts
  • Dr
  • Daniel
  • John
  • Pearce
  • Dr Daniel Pearce
  • Tel: 020 76794393
  • Ex: 34393
  • daniel.pearce@ucl.ac.uk
  • Website
  • https://iris.ucl.ac.uk/iris/extResource/image/01/DJPEA06
  • 2007-09-28
Address
  • 1019
  • Room 325 Darwin Building
  • Gower Street
  • London
  • WC1E 6BT
Joined UCL
  • 2007-09-28

Research Summary

Stem cells have been found in most tissues/organs. These stem cells produce replacements for lost and damaged cells, and it is not completely understood how this regenerative capacity becomes diminished during ageing. One hypothesis is that stem cells are more likely to sacrifice themselves than risk potentially cancer-causing damage being passed onto progeny. This should reduce the incidence of cancer, but ultimately, may lead to a reduction in stem cells with age that contributes to the ageing process.

Current research aims include;

  • Characterisation of age-based alterations in the phenotype and function of murine and human haematopoietic stem cells,
  • Analysis of the role of haematopoietic stem cell-specific antitoxicity mechanisms during ageing
  • Long-term tracking of the dynamics of age-based alterations in stem and progenitor cells
  • Analysis of stem cell epigenetic alterations during ageing and how this alters gene expression
  • Analysis of the effect of calorific restriction on murine haematopoietic stem ageing.


Research Activities
  • 853
  • Cell signalling
  • 766
  • The biology of ageing and the role of somatic stem cells in this process.

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Additional Information
  • ABC transporter
  • Ageing
  • Ageing of haematopoietic stem cells
  • Asymmetric cell division
  • Cancer progression
  • DNA damage
  • DNA repair
  • Human cell culture
  • Hypoxia
  • Oxidative stress
  • Stem cells
Collaborators
  • LPART24
  • prof dame linda partridge
  • DGEMS65
  • prof david gems
  • ESCHU11
  • dr eugene schuster
  • WSKHA12
  • mr wasim khan
  • MRDUC42
  • prof michael duchen
  • DMARS26
  • prof david marsh
  • RCHAR53
  • dr babis rallis
  • LFOUK88
  • dr lazaros foukas

Page last modified on 03 jul 13 14:22