Until recently an EU-funded postdoc in David Gems's lab, Alex Benedetto will shortly set up his own laboratory at the University of Lancaster, in the Department of Biomedical and Life Sciences. There he will continue his investigations of the biology of ageing in model organisms, particularly C. elegans. We wish Alex all the best in setting up his new lab! More...
Published: Jul 20, 2016 2:10:01 PM
New report on the origins of age-related disease in C. elegans More...
Published: Jul 20, 2016 2:04:41 PM
Congratulations to Dr Jorge Ivan Castillo Quan whose paper in Cell Reports was published today. His research, which was carried out during his PhD studies at the Institute of Healthy Ageing, demonstrates that fruit flies live 16% longer than average when given low doses of the mood stabiliser lithium. More...
Published: Apr 7, 2016 5:01:10 PM
dr daniel pearce
- Room 325 Darwin Building
- Gower Street
- WC1E 6BT
- Genetics, Evolution & Environment
- Div of Biosciences
Stem cells have been found in most tissues/organs. These stem cells usually produce replacements for lost and damaged cells, and it is not completely understood how this regenerative capacity becomes diminished during ageing.
- Analysis of the role of stem cell-specific anti-toxicity mechanisms during ageing
- Long-term tracking of the dynamics of age-based alterations in stem and progenitor cells
- Analysis of the effect of calorific restriction on murine haematopoietic stem ageing.
of stem cell epigenetic alterations during ageing and how this alters gene
- Cell signalling
- The biology of ageing and the role of somatic stem cells in this process.
AZD1152 rapidly and negatively affects the growth and survival of human acute myeloid leukemia cells in vitro and in vivo.
Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells.
Age dependent increase in SP distribution within Hematopoiesis: implications for our understanding of the mechanism of aging
Age-dependent increase in side population distribution within hematopoiesis: implications for our understanding of the mechanism of aging.
The combined use of Hoechst efflux ability and aldehyde dehydrogenase activity to identify murine and human hematopoietic stem cells.
- ABC transporter
- Ageing of haematopoietic stem cells
- Asymmetric cell division
- Cancer progression
- DNA damage
- DNA repair
- Human cell culture
- Oxidative stress
- Stem cells
- prof dame linda partridge
- prof david gems
- prof michael duchen
- prof david marsh
- dr lazaros foukas
Page last modified on 03 jul 13 14:22