Professor Linda Partridge was recently interviewed by Time Out London and features in today's issue ('Rad Scientists', Time Out, 20/09/2016). You can read the article via our Facebook site at https://www.facebook.com/UCLInstituteofHealthyAgeing/
Published: Sep 20, 2016 11:43:25 AM
Congratulations to Dr Teresa Niccoli whose paper "Increased Glucose Transport into Neurons Rescues Ab Toxicity in Drosophila" has just been published in Current Biology by Cell Press. More...
Published: Aug 17, 2016 3:05:35 PM
The Institute of Healthy Ageing is currently seeking a post-doctoral research associate to work on the following ARUK-funded project.
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating, mid-life, neurodegenerative disorders for which no cure is currently available. Large expansions of a hexanucleotide GGGGCC-repeat in the first intron of the C9orf72 gene is the most common genetic cause of both ALS and FTD. We recently developed novel Drosophila models of C9orf72 repeat-induced neurodegeneration (Mizielinska et al Science 2014, 345:1192-1194).
This 3-year post-doctoral position will build on this work by investigating disease mechanisms in a range of C9orf72 fly lines using several approaches including genome-wide transcriptomic and translational analyses in both flies and iPSC-neurons. You will work as part of a collaborative team of investigators in the excellent and supportive scientific research community of UCL.
The post is funded for 3 years in the first instance by Alzheimer’s Research UK and is available from October 2016.
For full information and to apply please visit the UCL website at https://goo.gl/E5vk8j
Published: Aug 11, 2016 2:27:25 PM
Professor Dame Linda Partridge works on the biology of ageing. Her research is directed to understanding both how the rate of ageing evolves in nature and the mechanisms by which healthy lifespan can be extended in laboratory model organisms. Her work has focussed in particular on the role of nutrient-sensing pathways, such as the insulin/insulin-like growth factor signalling pathway, and on dietary restriction. Her current work is directed to developing pharmacological treatments that ameliorate the human ageing process to produce a broad-spectrum improvement in health during ageing.
She is the recipient of numerous awards, including giving the Royal Society Croonian Lecture in 2009 and a DBE for Services to Science. She is a Fellow of the Royal Society, the Academy of Medical Sciences, the European Academy of Sciences and the American Academy of Arts and Sciences. She is the Director of the UCL Institute of Healthy Ageing, as well as founding director of the Max Planck Institute for Biology of Ageing in Cologne.
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