Until recently an EU-funded postdoc in David Gems's lab, Alex Benedetto will shortly set up his own laboratory at the University of Lancaster, in the Department of Biomedical and Life Sciences. There he will continue his investigations of the biology of ageing in model organisms, particularly C. elegans. We wish Alex all the best in setting up his new lab! More...
Published: Jul 20, 2016 2:10:01 PM
New report on the origins of age-related disease in C. elegans More...
Published: Jul 20, 2016 2:04:41 PM
Congratulations to Dr Jorge Ivan Castillo Quan whose paper in Cell Reports was published today. His research, which was carried out during his PhD studies at the Institute of Healthy Ageing, demonstrates that fruit flies live 16% longer than average when given low doses of the mood stabiliser lithium. More...
Published: Apr 7, 2016 5:01:10 PM
Aims of the Partridge Lab
The aim of our research is to discover genes and
mechanisms that determine the rate of ageing. We collaborate with
other laboratories to determine if these processes show evolutionary
conservation. Most of our work is conducted with the fruit fly Drosophila melanogaster through comparison with C.elegans and then with the mouse.
Our work focuses particularly on the insulin/IGF-like signalling pathway, dietary restriction and resistance to stress. We are interested also in the physiological mechanisms that force organisms to make trade-offs, such as that between high nutrient intake and high reproductive rate, on one hand and slow ageing on the other.
Our work is financed by the Wellcome Trust, the European Commission, ERC, MRC, Alzheimer's Research UK, Parkinsons' UK, The Glenn Foundation, Age UK and the Max Planck Institute.
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