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Congratulations to Dr Adam Dobson on his paper in Cell Reports

Congratulatsions to Adam Dobson and Nazif Alic whose paper, "Nutritional Programming of Lifespan by FOXO Inhibition on Sugar-Rich Diets," has just been published in Cell Reports. Their study shows that a history of feeding on a high sugar-diet shortens lifespan and changes gene expression. These changes appear to be mediated by FoxO/Daf16 in both flies and worms More...

Published: Jan 11, 2017 10:42:21 AM

Welcome to Matías Fuentealba

The IHA extends a warm welcome to Matías Fuentealba who joins Linda Partridge’s group this week as a PhD student. Matias recently completed his Masters in Biological Sciences at the Universidad de Chile, where his work comprised a “study of the energetics and structural characteristics of NAD and NADP binding sites through statistical potentials.” Welcome to London Matías!
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Published: Jan 10, 2017 11:44:35 AM

David Gems on BBC Radio 4 "Archive on 4"

On Saturday, November 26 2016 BBC Radio 4 broadcast a 1 hr programme entitled "Logan's Run and Intergenerational War", presented by Ed Howker, with extensive contributions from IHA Co-Director Professor David Gems. The programme included in depth discussion of the impact of the ageing of populations, and the prospects for treatments for ageing to improve late-life health. Among other contributors to the programme were former Universities and Science minister David Willetts and the actress Jenny Agutter.

The programme is available for a short period via the BBC iPlayer at http://www.bbc.co.uk/programmes/b083j672#play
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Published: Nov 30, 2016 12:53:17 PM

Arne Akbar

3 April 2012

20 September 2011


A study led by Professor Arne Akbar, Associate of the IHA, was published today.  The work focussed on ways to revitalise white blood cells that were thought to have been deactivated after fighting infections.

Previous research had suggested that white blood cells had a finite lifespan, meaning they gave less protection as a person aged.  This was thought to be determined by 'caps' on the end of DNA called telomeres which get shorter as the body fights infection.  Prof Akbar's team showed however that some white cells were inactive yet had long telomeres, suggesting another mechanism in the immune system was switching them off.  When they blocked off the newly identified pathway, they found that the white blood cells appeared to 'come to life' again.

For more on this story, see the following links:

Press coverage
Journal of Immunology
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