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Cell paper reveals how a cancer drug makes fruit flies live longer

A paper by researchers from the IHA Dr Cathy Slack and Dr Nazif Alic demonstrate new targets for drugs against ageing. Their research published in Cell shows how inhibition of the Ras-Erk-ETS pathway extends fly lifespan.
http://www.cell.com/cell/abstract/S0092-8674%2815%2900707-2 More...

Published: Jun 26, 2015 10:42:55 AM

Dr Jorge Ivan Castillo Quan - Anti-Aging: Beauty or Health?

Watch the IHA's Dr Jorge Ivan Castillo Quan's talk on Anti-Aging. His fascinating talk was part of a very successful event called TEDx held at Goodenough College. More...

Published: Jun 17, 2015 12:38:48 PM

Brain paper published by Partridge Lab

Research staff from the IHA's Partridge Lab, including Dr Jorge Ivan Castillo Quan and PhD student Ms Li Li, are among those whose work has recently been published in Brain. Their paper is entitled, "Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction".
More...

Published: Jun 11, 2015 2:42:41 PM

Arne Akbar

3 April 2012

20 September 2011


A study led by Professor Arne Akbar, Associate of the IHA, was published today.  The work focussed on ways to revitalise white blood cells that were thought to have been deactivated after fighting infections.

Previous research had suggested that white blood cells had a finite lifespan, meaning they gave less protection as a person aged.  This was thought to be determined by 'caps' on the end of DNA called telomeres which get shorter as the body fights infection.  Prof Akbar's team showed however that some white cells were inactive yet had long telomeres, suggesting another mechanism in the immune system was switching them off.  When they blocked off the newly identified pathway, they found that the white blood cells appeared to 'come to life' again.

For more on this story, see the following links:

Press coverage
Journal of Immunology
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Page last modified on 03 apr 12 10:05