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Jorge Ivan Castillo Quan on Anti-Ageing research

'Anti-Ageing: Health or Beauty?' A guest blog by Jorge Ivan Castillo Quan, written for the 2015 Write About Research Competition.

http://blogs.ucl.ac.uk/…/2…/07/07/anti-ageing-health-beauty/ More...

Published: Jul 8, 2015 11:51:04 AM

Talks from Gems Lab at International C. elegans Meeting

Dr Marina Ezcurra and Dr Alex Benedetto were both selected to speak at the recent International C. elegans Meeting in Los Angeles (June 24th-28th). The two talks described new breakthroughs in understanding the mechanisms by which age-related pathologies originate in C. elegans, and generated considerable interest. Alex also described a new stress-resistance assay based on death fluorescence, recently discovered in the Gems lab. For details of the C. elegans International Meeting see http://www.genetics-gsa.org/celegans/2015/ More...

Published: Jul 7, 2015 11:01:37 AM

Institute of Healthy Ageing hosts BSRA Annual Meeting

The 65th British Society for Research on Ageing Annual Meeting took place at the Institute of Healthy Ageing on July 1st-2nd 2015. Speakers at the conference included Claudio Franceschi (Bologna), Paul Shiels (Glasgow), Jesus Gil (Imperial), and Avan Aihie Sayer (Southampton). They also included several speakers from the IHA: Lazaros Foukas, who described how ageing can be slowed down in mice by reducing PI3 kinase signalling, Cathy Slack (whose talk was awarded the Korenchevsky Prize) spoke about how Ras signalling controls fruitfly ageing, and David Gems who gave a welcome address, including a discussion of “The ageing-disease false dichotomy”.
For further information about the meeting see http://www.bsra.org.uk/node/842 More...

Published: Jul 7, 2015 10:59:19 AM

Arne Akbar

3 April 2012

20 September 2011

A study led by Professor Arne Akbar, Associate of the IHA, was published today.  The work focussed on ways to revitalise white blood cells that were thought to have been deactivated after fighting infections.

Previous research had suggested that white blood cells had a finite lifespan, meaning they gave less protection as a person aged.  This was thought to be determined by 'caps' on the end of DNA called telomeres which get shorter as the body fights infection.  Prof Akbar's team showed however that some white cells were inactive yet had long telomeres, suggesting another mechanism in the immune system was switching them off.  When they blocked off the newly identified pathway, they found that the white blood cells appeared to 'come to life' again.

For more on this story, see the following links:

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Journal of Immunology
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