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Congratulations to Dr Teresa Niccoli on her paper in Current Biology

Congratulations to Dr Teresa Niccoli whose paper "Increased Glucose Transport into Neurons Rescues Ab Toxicity in Drosophila" has just been published in Current Biology by Cell Press. More...

Published: Aug 17, 2016 3:05:35 PM

ARUK funded post-doc position available at the IHA

The Institute of Healthy Ageing is currently seeking a post-doctoral research associate to work on the following ARUK-funded project.

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating, mid-life, neurodegenerative disorders for which no cure is currently available. Large expansions of a hexanucleotide GGGGCC-repeat in the first intron of the C9orf72 gene is the most common genetic cause of both ALS and FTD. We recently developed novel Drosophila models of C9orf72 repeat-induced neurodegeneration (Mizielinska et al Science 2014, 345:1192-1194).

This 3-year post-doctoral position will build on this work by investigating disease mechanisms in a range of C9orf72 fly lines using several approaches including genome-wide transcriptomic and translational analyses in both flies and iPSC-neurons. You will work as part of a collaborative team of investigators in the excellent and supportive scientific research community of UCL.

The post is funded for 3 years in the first instance by Alzheimer’s Research UK and is available from October 2016.

For full information and to apply please visit the UCL website at https://goo.gl/E5vk8j
More...

Published: Aug 11, 2016 2:27:25 PM

Lectureship for Alexandre Benedetto

Until recently an EU-funded postdoc in David Gems's lab, Alex Benedetto will shortly set up his own laboratory at the University of Lancaster, in the Department of Biomedical and Life Sciences. There he will continue his investigations of the biology of ageing in model organisms, particularly C. elegans. We wish Alex all the best in setting up his new lab! More...

Published: Jul 20, 2016 2:10:01 PM

Fiona Kerr - Alzheimer's Association International Conference highlights

23 July 2012

Dr Fiona Kerr (Partridge Lab) attended the AAIC in Vancouver, 14th-19th July 2012 last week.

Fiona writes: Over the last three years Genome Wide Association Studies (GWAS) have led to the discovery of variants in 10 new genes which associate with increased risk of developing late-onset Alzheimer’s disease (LOAD). This has required an unprecedented level of collaboration within the AD field, pulling together clinical cohorts world-wide in order to achieve the large data-sets required to obtain meaningful findings in such studies. At this year’s AAIC the excitement re-instated in Alzheimer’s by this research was evident, with scientists looking toward the post-GWAS era of AD discovery. We need to understand more about the effect of these AD-risk variants on gene expression and function, and their potential role in the development of Alzheimer’s disease pathology. If any of these genes are found to play a causal role in AD pathogenesis, beyond simply associating with increased risk for disease development, this could uncover potential new therapeutic targets for the prevention and treatment of LOAD.

Page last modified on 23 jul 12 13:34