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Congratulations to Dr Adam Dobson on his paper in Cell Reports

Congratulatsions to Adam Dobson and Nazif Alic whose paper, "Nutritional Programming of Lifespan by FOXO Inhibition on Sugar-Rich Diets," has just been published in Cell Reports. Their study shows that a history of feeding on a high sugar-diet shortens lifespan and changes gene expression. These changes appear to be mediated by FoxO/Daf16 in both flies and worms More...

Published: Jan 11, 2017 10:42:21 AM

Welcome to Matías Fuentealba

The IHA extends a warm welcome to Matías Fuentealba who joins Linda Partridge’s group this week as a PhD student. Matias recently completed his Masters in Biological Sciences at the Universidad de Chile, where his work comprised a “study of the energetics and structural characteristics of NAD and NADP binding sites through statistical potentials.” Welcome to London Matías!
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Published: Jan 10, 2017 11:44:35 AM

David Gems on BBC Radio 4 "Archive on 4"

On Saturday, November 26 2016 BBC Radio 4 broadcast a 1 hr programme entitled "Logan's Run and Intergenerational War", presented by Ed Howker, with extensive contributions from IHA Co-Director Professor David Gems. The programme included in depth discussion of the impact of the ageing of populations, and the prospects for treatments for ageing to improve late-life health. Among other contributors to the programme were former Universities and Science minister David Willetts and the actress Jenny Agutter.

The programme is available for a short period via the BBC iPlayer at http://www.bbc.co.uk/programmes/b083j672#play
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Published: Nov 30, 2016 12:53:17 PM

Fiona Kerr - Alzheimer's Association International Conference highlights

23 July 2012

Dr Fiona Kerr (Partridge Lab) attended the AAIC in Vancouver, 14th-19th July 2012 last week.

Fiona writes: Over the last three years Genome Wide Association Studies (GWAS) have led to the discovery of variants in 10 new genes which associate with increased risk of developing late-onset Alzheimer’s disease (LOAD). This has required an unprecedented level of collaboration within the AD field, pulling together clinical cohorts world-wide in order to achieve the large data-sets required to obtain meaningful findings in such studies. At this year’s AAIC the excitement re-instated in Alzheimer’s by this research was evident, with scientists looking toward the post-GWAS era of AD discovery. We need to understand more about the effect of these AD-risk variants on gene expression and function, and their potential role in the development of Alzheimer’s disease pathology. If any of these genes are found to play a causal role in AD pathogenesis, beyond simply associating with increased risk for disease development, this could uncover potential new therapeutic targets for the prevention and treatment of LOAD.

Page last modified on 23 jul 12 13:34