Congratulations to Dr Teresa Niccoli whose paper "Increased Glucose Transport into Neurons Rescues Ab Toxicity in Drosophila" has just been published in Current Biology by Cell Press. More...
Published: Aug 17, 2016 3:05:35 PM
The Institute of Healthy Ageing is currently seeking a post-doctoral research associate to work on the following ARUK-funded project.
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating, mid-life, neurodegenerative disorders for which no cure is currently available. Large expansions of a hexanucleotide GGGGCC-repeat in the first intron of the C9orf72 gene is the most common genetic cause of both ALS and FTD. We recently developed novel Drosophila models of C9orf72 repeat-induced neurodegeneration (Mizielinska et al Science 2014, 345:1192-1194).
This 3-year post-doctoral position will build on this work by investigating disease mechanisms in a range of C9orf72 fly lines using several approaches including genome-wide transcriptomic and translational analyses in both flies and iPSC-neurons. You will work as part of a collaborative team of investigators in the excellent and supportive scientific research community of UCL.
The post is funded for 3 years in the first instance by Alzheimer’s Research UK and is available from October 2016.
For full information and to apply please visit the UCL website at https://goo.gl/E5vk8j
Published: Aug 11, 2016 2:27:25 PM
Until recently an EU-funded postdoc in David Gems's lab, Alex Benedetto will shortly set up his own laboratory at the University of Lancaster, in the Department of Biomedical and Life Sciences. There he will continue his investigations of the biology of ageing in model organisms, particularly C. elegans. We wish Alex all the best in setting up his new lab! More...
Published: Jul 20, 2016 2:10:01 PM
Origins of the IHA
Work on the creation of the UCL Institute of Healthy Ageing began in March 2004 and was taken forward by a large team, including a cross-faculty Steering Committee whose membership included Prof Arne Akbar, Prof Ed Byrne, Prof Leon Fine, Prof David Gems, Prof Bob Lieberman, Prof Peter Mobbs, Prof Dame Linda Partridge, Dr Mary Phillips, Prof Mike Spyer, Prof Patrick Vallance and Prof Dominic Withers, with strong support from the UCL Provost, Prof Malcolm Grant.
Development and Governance of the IHA
The Institute of Healthy Ageing replaced the earlier Centre for Research on Ageing in Autumn 2007.
The Institute now hosts the labs of six PI's with numerous funding sources between them including the Wellcome Trust, The Royal Society and the MRC. In addition to the substantial labs of Prof Dame Linda Partridge and Prof David Gems, the labs of the following staff are housed within the IHA in UCL's Darwin Building:
- Dr Daniel Pearce joined the IHA in Autumn 2007, on a tenure track position with an RCUK Fellowship, to set up a new research group working on ageing in haematopoietic stem cells.
- Dr Eugene Schuster, previously of the European Bioinformatics Institute, joined the IHA in January 2008 as an MRC Senior Research Fellow. His research utilises functional genomic approaches to understand long-lived animal models.
- Dr Lazaros Foukas joined as a Lecturer in June 2009 to study the signalling pathways that control mammalian ageing.
- Dr Matt Piper, already a post-doc in the Partridge lab, was awarded his own Fellowship by the Royal Society in August 2011. His work focuses on Dietary Restriction (DR or calorie restriction) - an evolutionarily conserved intervention that extends healthy lifespan.
The activities of the IHA were given a strong boost by a £5.1
million Strategic Award from the Wellcome Trust in 2006 and achieved further success by obtaining a second Strategic Award commencing 2013.
Strategic management of the IHA
A strategic overview of the activities of the IHA is maintained by its Steering Committee. All PI's within the Institute are members of the Steering Committee along with Michael Wright (Executive Officer) and Giovanna Vinti (Laboratory Manager) who together represent the support activities. The Committee meets quarterly to discuss and review the latest research and strategic plans.
Max Planck Institute for Biology of Ageing
In 2010 Linda Partridge took on an additional role
as a founding director of the new Max Planck Institute in Cologne
dedicated to the biology of ageing. The close links that have since developed between
the IHA and the MPI continue to help strengthen and enliven both institutions.
Page last modified on 03 jul 13 10:59