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IHA News

Dr Nazif Alic paper published in PLOS Genetics

In their recent paper in PLOS Genetics Alic and co-workers explore the complex relationship between Drosophila foxo, a transcription factor with evolutionarily conserved role in ageing, and Anterior open, an ETS-family transcription factor that is a direct target of dFOXO in the adult gut and whose activation can extend lifespan.

The paper is entitled, "Interplay of dFOXO and Two ETS-Family Transcription Factors Determines Lifespan in Drosophila melanogaster"

View the article here: http://tinyurl.com/off4cqq More...

Published: Sep 19, 2014 9:58:55 AM

Gems Lab Summer Roundup

Congratulations to Jennifer Tullet (again!)

In September, Dr Jennifer Tullet will cease to be a postdoc, and take up
a Principle Investigator position running her own lab at the University
of Kent, where she will continue her investigations of ageing in C.
elegans. Jennifer also recently spoke at the American Aging Association
meeting in San Antonio, Texas, and recently published a paper entitled
“DAF-16 target identification in C. elegans: past, present and future”
in the journal Biogerontology.

Congratulations to Dr Yila de la Guardia!

Yila de la Guardia recently passed her Ph.D. viva (examiners, Prof Bart
Braeckman from the University of Ghent, and Dr Lazaros Foukas from the
IHA). Yila has now returned to Panama, and she is much missed.

New members of the lab

The lab welcomes three new members! Dr Yuan Zhao moved to the lab from
Cancer Research UK, London, where she worked on telomeres in fission
yeast with Dr Julie Cooper; and Dr Evgeniy Galimov from the National
Research Centre for Preventive Medicine, Moscow, where he worked on ROS
signalling and p66shc with Prof Viktor Skulachev. Both positions are
funded by the Wellcome Trust. Welcome also to Thanet Sornda who recently
started Ph.D. research in the lab. Thanet previously did a Master’s
degree at the Institute of Ageing and Health, Newcastle University, and
is funded by the state of Thailand.

News about David Gems

David gave various talks, e.g. at the Genetics of Aging and Longevity
meeting in Sochi (April), Russia, the British Society for Research on
Ageing meeting in Liverpool (July), and at Oxford and Cambridge
universities. He recently published two essays: 'What is an anti-aging
treatment?' Exp. Gerontol. (2014) 58: 14-18; and 'Evolution of sexually
dimorphic longevity in humans.' Aging (2014) 6: 84-91.
More...

Published: Sep 4, 2014 5:02:16 PM

Congratulations to Adam Dobson

Congratulations to Dr Adam Dobson who has been awarded a grant from the Cornell Center for Comparative and Population Genomics to study how the Drosophila gut changes in response to nutritional manipulations. This will establish a collaboration between the Piper lab and Dr Nicolas Buchon at Cornell University.
More...

Published: Sep 4, 2014 4:58:38 PM

About us


The Institute of Healthy Ageing (Director: Prof Dame Linda Partridge, DBE, FRS, FRSE, FMedSci) is an interdisciplinary centre of excellence for research on the biology of ageing and ageing-related diseases. The biological process of ageing contributes to increased risk of a wide range of diseases, from neurodegenerative diseases (e.g. Alzheimer's and Parkinson's disease) and cancer to cardiovascular disease (causing heart attack and stroke) and age-related macular degeneration (causing blindness in the elderly).

Our primary purpose is to bring together researchers working on the basic biology of ageing (biogerontology) with those working to understand the causes of ageing-related disease. By merging the two, we aim to develop a new translational biogerontology using the ageing process as a point of intervention to protect against the diseases of old age. Our goal is to improve the health and quality of life for older people.

The work of the Institute of Healthy Ageing is pursuing these ends by:

  • Conducting world class research on the biology of ageing and ageing-related disease
  • Increasing capacity in research on the biology of ageing by training new researchers and nurturing the work of younger principal investigators
  • Teaching about the biology of ageing at undergraduate and postgraduate levels

The problem of ageing is not just an issue of biology, but also of social science, economics and the built environment. A secondary aim of the Institute is to nurture broader collaborations across UCL between researchers working on different aspects of ageing.

We aim, through our combined activities, to transform healthcare technology and the social conditions of the elderly to create a future society in which the lives of older people are healthy, meaningful and happy. 

Our facilities are shared with the associated Bähler Lab, headed by Professor Jürg Bähler.

Page last modified on 03 jul 13 14:38