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TBTVACC: Developing a partnership to inform UK-Brazil TB control

Developing a partnership to inform UK-Brazil TB control. Investigating the efficacy of BCG vaccination following latent tuberculosis treatment

Project Summary

The overall aim of this collaboration is to develop a partnership that would bring together two major programmes of work in epidemiology in the UK and immunology in Brazil to inform the development of a major trial that would assess whether the efficacy of BCG vaccination in individuals with latent TB infection (LTBI) is improved by treating pre-existing latent infection.

The project includes a literature review, mathematical modelling and a pilot randomised controlled trial in Brazil on the efficacy of BCG following treatment of latent TB infection.

Links to other research

Other research from IGH on TB, Prevention, Population Health, Global Health and Development and Vulnerable Populations & Disability

Other research from IGH in Brazil