- Funded PhD Studentship at the UCL Research Department of Infection and Population Health
The EuroSIDA study is a prospective observational cohort study of more than 22000 patients followed in 107 hospitals in 35 European countries plus Israel and Argentina (details at http://www.cphiv.dk/Ongoing-Studies/EuroSIDA/About). The main objective of the study is to follow the long-term clinical prognosis for the general population of HIV-infected patients living in Europe and to assess the impact of antiretroviral drugs on the long-term prognosis for these patients. The EuroSIDA study was initiated in 1994 and is one of the most successful HIV observational cohorts worldwide. The study continues to expand in multiple ways. Being an observational study, the type of data collected has diversified tremendously since the start, as advances in the medical management of HIV has allowed for HIV-infected patients to foresee a good life prognosis. The study has recently initiated a new cohort of 5000 patients coinfected with HIV and hepatitis C (HCV), to study the introduction of direct acting antivirals (DAAs), how these new drugs are being used, outcomes and toxicities.
Treatment levels for HCV in Europe remain low and have traditionally been limited by contraindications to interferon-based therapy and low treatment efficacy of pegylated-interferon plus ribavirin. However, the recent approval of DAAs for HCV means that fewer coinfected individuals will have contraindications to HCV treatment, while treatment efficacy will be significantly improved with sustained virologic response (SVR) rates >90% expected. Whether the SVR and outcomes seen in clinical trials are seen in routine clinical practice remain to be seen. Further, the approximate costs of €50,000-90,000 per treatment for DAAs will necessitate the prioritisation of individuals for treatment across Europe. A number of key questions would form the basis of this PhD including:
• Inter and intra-regional variation in the uptake of DAAs
• Virological response to DAAs across a heterogeneous European population
• Clinical outcomes in persons exposed to DAAs, including both liver and non-liver related mortality and morbidity
• Range of adverse events experienced among persons exposed to DAAs and predictors and outcomes of adverse events
• Adverse events, virological responses and outcomes following repeated exposure to DAAs
Applicants should have a first or upper second class degree in a mathematical subject and an MSc (or shortly to be completed) in medical statistics or strongly related subject. Applicants should be familiar with, or willing to learn SAS (Statistical Analysis Software) for programming and be willing to undertake regular trips to the Centre for Health and Diseases Infectious Diseases Research (CHIP) in Copenhagen, Denmark (http://www.cphiv.dk/Home/About). The applicant will also be expected to contribute to improving data quality in the EuroSIDA database and to actively contribute to the EuroSIDA hepatitis research agenda.
Due to funding restrictions, applicants must be UK/EU nationals. EU applicants must have been a resident in the UK for three years immediately prior to starting a PhD to be eligible. If you do not fulfill this criterion, you are not eligible for this scheme.
This research studentship is for 4 years and will start in the 2016/17 academic year.
Due to funding restrictions, studentships cover UK/EU fees only and full stipend for four years. The stipend is currently £19,000 pa.
Applications should include
• CV including full details of all University courses and grades to date
• A statement of research experience and interests
• How and why the applicant is suited to this specific PhD position.
Electronic submissions are preferred. Please include a contact telephone number and an email address. The covering letter should be no longer than 2 pages. Applications should be emailed to: Pat Withington (firstname.lastname@example.org) or posted to UCL Royal Free Campus, Research Department of Infection and Population Health, Room 656, Level 1, Rowland Hill Street, London, NW3 2PF.
Application deadline: 21st July 2016
If you wish to discuss any aspect of this PhD, please contact Professor Amanda Mocroft, email@example.com. The PhD will be jointly supervised by Professor Amanda Mocroft at UCL and Dr Lars Peters at CHIP.
Interview date: 28th July 2016
- Improving the Governance of Medication Safety
The National Institute of Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care (CLAHRC) North Thames is accepting applications for its 2015/2016 PhD studentship. NIHR CLAHRC North Thames is one of 13 CLAHRCs across England which have been funded to conduct high quality applied health research, focused on the needs of patients and the public to produce a direct impact on health and the way that health care/public health is organised and delivered. More information about the CLAHRC can be found on our website: http://www.clahrc-norththames.nihr.ac.uk/
This PhD builds on UCL research undertaken on governance processes of medication safety in acute hospitals and professional engagement with these processes. This research will analyse how specific medication safety cultures develop in a variety of clinical contexts based on differences in professional culture (e.g. among doctors, nursing staff, and pharmacists). Service areas with different theorised attitudes toward medication safety may also be compared, such as surgery and general medicine.
The PhD study may include developing and piloting an intervention for tackling these boundaries.
Skills / experience required
- Training in one or more of the social sciences is essential.
- Experience in qualitative research methods, particularly ethnographic research, is desirable.
- Knowledge of the UK NHS is essential.
Methods to be used
- Systematic narrative review of the patient safety literature, drawing on different disciplines/perspectives (e.g. relevant work on organisational learning/ governance processes/ innovation studies).
- Ethnographic methods, which involve spending an extended period of time in different clinical settings to acquire a detailed understanding of the ‘safety culture’. Ethnography in each setting will draw on non-participant observations, formal and informal interviews, and documentary analysis.
• Professor Naomi Fulop, UCL, firstname.lastname@example.org
• Dr Yogini Jani, UCLH, email@example.com
• Professor Martin Marshall, UCL, firstname.lastname@example.org
• Dr Simon Turner, UCL, email@example.com
Due to funding restrictions applicants must be UK/EU nationals. Please refer to UK Council for International Student Affairs (UKCISA) for details of these criteria: http://www.ukcisa.org.uk/International-Students/Fees--finance/Home-or-Overseas-fees/
PhD students will be entitled to the full range of PhD training opportunities at their host institution. In addition, all PhD students benefit from training provided by the NIHR CLAHRC North Thames Academy. The Academy brings together PhD students from across the CLAHRC, to create a community of students training in applied health research. The Academy works alongside each host institution’s graduate training programme to equip students with the skills needed to work at the interface of academia and health services. Our doctoral programme focuses on practical aspects of applied health research, such as the skills required to undertake research in health care and public health settings, to engage patients and the public in research, and to navigate relevant ethical and research governance approval systems. In addition, we aim to provide students with an understanding of how their work fits in to current NHS structures, for example by facilitating short shadowing placements. PhD students will be expected to attend and present at scientific meetings aimed at disseminating the findings of CLAHRC research.
Further information on the studentship:
This is an exciting opportunity for applicants with an interest in further developing social science skills in applied health research to take up a PhD studentship funded by The Health Foundation within the Department of Applied Health Research, University College London. The student will join the Organisation and Management of Health Care group, led by Professor Naomi Fulop, and link with a broader programme of research funded by NIHR Collaborations for Leadership in Applied Health Research and Care (CLAHRC) North Thames within the theme innovations in systems and models of care.
The PhD provides an opportunity to draw on evidence from different social science disciplines on the impact of professional and organisational culture on processes of learning and improvement relevant to patient safety; to explore the ways in which intra- and inter-professional boundaries influence the prevailing ‘safety culture’ in different acute care settings; and to investigate factors likely to improve the safety culture in consultation with a range of healthcare professionals.
If you would like further information on the PhD topic please contact Michelle Morton firstname.lastname@example.org.
How to apply:
Candidates should hold a Master’s qualification in an appropriate discipline and have a minimum of a 2:1 or equivalent in their first degree. Candidates should be able to demonstrate academic training in one or more of the social sciences. All applicants are required to have excellent written and verbal communication skills. They should also be willing to work collaboratively in multi-disciplinary and multi-professional teams.
Your application should consist of a CV and contact details of two academic referees. You must also include a personal statement (1,000 words maximum) describing your suitability for the project including how your research experience and interests relate to the project.
Please send your application to Mary Thomas, NIHR CLAHRC North Thames Manager (email@example.com).
Closing date for applications: Sunday 14 February 2016
Interviews: w/c 22 February 2016
Duration: 3 years, full time
- UCL-Birkbeck MRC Doctoral Training Programme
The UCL-Birkbeck MRC Doctoral Training Programme provides state-of-the-art PhD training across four strategic themes that exploit the unique research strengths and training infrastructure of UCL and Birkbeck. This enables us to support the brightest and most promising scientists who wish to undertake rigorous research training at UCL and Birkbeck. The guiding principles of our programme are to encourage students to consider a broad range of PIs in four broad themes as potential supervisors, and to mentor them through their PhD to postdoctoral fellowships and other career opportunities.
Applications are invited annually. You do not need to have studied at UCL or Birkbeck previously to apply, and the programme will provide a fully funded four year research studentship to allow talented scientists to sample high quality research environments at Birkbeck and UCL before they develop a research proposal tailored to their individual interest. The UCL SLMS Academic Careers Office will provide advice and support. At the end of the PhD we expect students to have acquired both specific research skills and a broader portfolio of transferable skills that will equip them for their future careers and facilitate their progression as academic leaders of the future.
Full information about the Doctoral Traning programme can be found on UCL SLMS' webpages: https://www.ucl.ac.uk/slms/aco/bat/programmes/mrc_dtp
Further opportunities can sometimes be found on local Research Departmental vacancy pages via the below links, or on UCL's HR webpages.
|EPH||Epidemiology & Public Health|
|IPH||Infection & Population Health|
|PCPH||Primary Care & Population Health|
|MRC LHA||MRC Unit of Lifelong Health and Ageing|