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Laboratory services

ICH Embryonic stem cell / Chimera production facility

Publications

  1. Cynthia L. Andoniadou, Massimo Signore, Ezat Sajedi, Carles Gaston-Massuet, Daniel Kelberman, Alan J. Burns, Nobue Itasaki, Mehul Dattani and Juan Pedro Martinez-Barbera. Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain (2007)Development 134, 1499-1508
  2. Patricia Ybot-Gonzalez, Dawn Savery, Dianne Gerrelli, Massimo Signore, Claire E. Mitchell, Clare H. Faux, Nicholas D. E. Greene and Andrew J. Copp. Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure (2007) Development. 134(4):789-99
  3. Ivanova A, Signore M, Caro N, Greene ND, Copp AJ, Martinez-Barbera JP. (2005). In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A. Genesis 43, 129-35
  4. Bort R, Signore M, Tremblay K, Martinez Barbera JP, Zaret KS. (2005. Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development.. Dev. Biol. 290, 44-56.
  5. DNMT1 interacts with the developmental transcriptional repressor HESX1. Ezat Sajedi, Carles Gaston-Massuet, Cynthia L. Andoniadou, Massimo Signore, Paul J. Hurd, Mehul Dattani and Juan Pedro Martinez-Barbera. Biochimica et Biophysica Acta (BBA) Molecular Cell Research. Volume 1783, Issue 1, January 2008, Pages 131-143.
  6. Genetic interaction between the homeobox transcription factors HESX1 and SIX3 is required for normal pituitary development. Carles Gaston-Massuet, Cynthia L. Andoniadou, Massimo Signore, Ezat Sajedi, Sophie Bird, James M.A. Turner and Juan Pedro Martinez-Barbera. Dev Biol. 2008 Dec 15, Volume 324, Issue 2, 15 December 2008, Pages 322-333.
  7. Analysis of mouse models carrying the I26T and R160C substitutions in the transcriptional repressor HESX1 as models for septo-optic dysplasia and hypopituitarism. Sajedi E, Gaston-Massuet C, Signore M, Andoniadou CL, Kelberman D, Castro S, Etchevers HC, Gerrelli D, Dattani MT, Martinez-Barbera JP. Disease Models and Mechanisms 2008 Nov-Dec;1(4-5):241-54. Epub 2008 Nov 6.
  8. Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes. Pauws E, Hoshino A, Bentley L, Prajapati S, Keller C, Hammond P, Martinez-Barbera JP, Moore GE, Stanier P. Hum Mol Genet. 2009 Nov 1;18(21):4171-9. Epub 2009 Jul 31.

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