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UCL Great Ormond Street Institute of Child Health

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Nervous System Development and Disease Research Group

Neural Tube Research

Research in the Neural Tube Group focuses on the embryonic processes of early nervous system development and the origin of neurulation disorders, termed 'neural tube defects' (NTDs).  Follow the links below to read more about particular aspects of our research:

Mechanisms of neurulation and NTDs

Planar cell polarity genes and neurulation

Prevention of NTDs by inositol: The PONTI study

Non-Ketotoic Hyperglycinemia

Human Developmental Biology Resource

Folate one-carbon metabolism and neural development