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Recent publications

 
 
Beyerlein A, Hadders-Algra M, Kennedy K, Fewtrell M, Singhal A, Rosenfeld E, Lucas A, Bouwstra H, Koletzko B, von Kries R. Infant Formula Supplementation with long-chain polyunsaturated fatty acids has no effect on Bayley Developmental Scores at 18 months of age – IPD meta-analysis of 4 large clinical trials.J Pediatr Gastroenterol Nutr 2010; 50: 79-84
Fewtrell MS, Wilson DC, Booth I, Lucas A. Six months of exclusive breastfeeding: How good is the evidence? BMJ 2010
Fewtrell MS. Commentaries on Premastication: the second arm of infant and young child feeding for health and survival? Matern Child Nutr 6(1): 21-22
Haroun D, Taylor SJ, Viner RM, Hayward RS, Darch TS, Eaton S, Cole TJ, Wells JC. Validation of Bioelectrical Impedance Analysis in Adolescents Across Different Ethnic Groups. Obesity (Silver Spring) 2010; 18: 1252-9
Isaacs EB, Fischl BR, Quinn BT, Chong WK, Gadian DG, Lucas A. Impact of breast milk on IQ, brain size and white matter development. Ped Research 2010; 67: 357-362
Isaacs EB. The effect of early diet on brain and cognition. In Lifetime nutritional influences on cognition, behaviour and psychiatric illness. Ed D Benton. Wroxhead Publishing Bristol.
Kennedy K, Ross S, Isaacs EB, Weaver LT, Singhal A, Lucas A, Fewtrell MS. Ten year follow-up of a randomised trial of long-chain polyunsaturated fatty acid supplementation in preterm infants: Effects on growth and blood pressure. ADC 2010; 95: 588-95
Lanigan J, Barber S, Singhal A. Session 3 (Joint with the British Dietetic Association): Management of obesity Prevention of Obesity in Preschool Children. Proc Nutr Soc 2010; 69: 204-10

Lazdam M, de la Horra A, Pitcher A, Mannie Z, Diesch J, Trevitt C, Kylintireas I, Contractor H, Singhal A, Lucas A, Neubauer S, Kharbanda R, Alp N, Kelly B, Leeson P

Elevated blood pressure in offspring born premature to hypertensive pregnancy: Is endothelial dysfunction the underlying vascular mechanism? Hypertension 2010; 56: 34-5
Reilly JJ, Gerasimidis K, Paparacleous N, Sherriff A, Carmichael A, Ness AR, Wells JC. Validation of dual-energy x-ray absorptiometry and foot-foot impedance against deuterium dilution measures of fatness in children. Int J Pediatr Obes 2010; 5: 111-5
Reilly JJ, Dorosty AR, Ghomizadeh NM, Sherriff A, Wells JC, Ness AR. Comparison of waist circumference percentiles versus body mass index percentiles for diagnosis of obesity in a large cohort of children. Int J Pediatr Obes 2010; 5: 151-6
Sacher PM, Kolotourou M, Chadwick P, Cole TJ, Lawson M, Lucas A, Singhal A. Randomized controlled trial of the MEND Program: a family-based community intervention for childhood obesity. Obesity 2010; 18, suppl 1, S62-8
Siervo M, Wells J. Aggregate prediction of resting energy expenditure may perform better than individual estimates.  Clin Nutr 2010; 29: 347-51
Singhal A, Kennedy K, Lanigan J, Fewtrell M, Cole TJ, Stephenson T, Elias-Jones A, , Weaver LT, Ibhanesebhor S, MacDonald P, Bindels J, Lucas A. Nutrition in Infancy and Long-term Risk of Obesity; Evidence from Two Randomised Controlled Trials. AJCN 2010; 92: 1133-44 
Singhal A.  Does early growth affect long-term risk factors for cardiovascular disease?  Nestle Nutr Workshop Ser Pediatr Program 2010; 65: 55-69 
Stephan BC, Wells JC, Brayne C, Albanese E, Siervo M. Increased fructose intake as a risk factor for dementia. J Gerontol A Biol Sci Med Sci 2010; 65(8): 809-14
Sullivan S, Schanler RJ, Kim JH, Patel AL, Trawoger R, Kiechl-Kohlendorfer U, Chan GM, Blanco CL, Abrams S, Cotton M, Laroia N, Ehrenkranz RA, Dudell G, Cristofalo EA, Meier P, Lee ML, Rechtman DJ, Lucas A. An exclusively human milk-based diet is associated with a lower rate of necrotising enterocolitis than a diet of human milk and bovine milk-based products. J Pediatr 2010; 156: 562-7
Viner RM, Fry T, Gupta S, Kinra S, McCarthy D, Saxena S, Taylor S, Wells JC, Whincup P, Zaman MJ. Insufficient evidence to support separate BMI definitions for obesity in children and adolescents from south Asian ethnic groups in the UK. Int J Obes 2010; 34: 656-8
Wells JC, Haroun D, Williams JE, Wilson C, Darch T, Viner RM, Eaton S, Fewtrell MS. Evaluation of DXA against the four-component model of body composition in obese children and adolescents aged 5 to 21 years. Int J Obes 2010; 34: 649-55
Wells JC. Maternal capital and the metabolic ghetto: An evolutionary perspective on the transgenerational basis of health inequalities. Am J Hum Biol 2010; 22: 1-17
Wells JC, Williams JE, Chomtho S, Darch T, Grijalva-Eternod C, Kennedy K, Haroun D, Wilson C, Cole TJ, Fewtrell MS. Pediatric reference data for lean tissue properties: density and hydration from age 5 to 20 y. Am J Clin Nutr 2010; 91: 610-8
Wells JC, Griffin L, Treleaven P. Independent changes in female body shape with parity and age: A life-history approach to female adiposity. Am J Hum Biol 2010; 22: 456-62
Wells JC. Evolutionary aspects of obesity and adipose tissue function. In: Adipose tissue 1 health and disease, ed Leff T, Granneman G. Wiley-VCH Verlag GmBH & Co., Weinheim 2010: 473-490
Williams JE, Wells JC, Benden C, Jaffe A, Suri R, Wilson CM, Fewtrell MS.  Body composition assessed by the four-component model and association with lung function in 6 to 12 year old children with cystic fibrosis.  Am J Clin Nutr 2010; 92: 1-12
Chomtho S, Wells JC, Davies PS, Lucas A, Fewtrell MS (2009) Early growth and body composition in infancy. Adv Exp Med Biol 646: 165–8.

Fewtrell MS, Williams JE, Singhal A, Murgatroyd PR, Fuller N, Lucas A (2009) Early diet and peak bone mass: 20 year follow-up of a randomized trial of early diet in infants born preterm. Bone 45 (1): 142–9.

Ong KK, Emmett P, Northstone K, Golding J, Rogers I, Ness AR, Wells JC, Dunger DB (2009) Infancy weight gain predicts childhood body fat and age at menarche in girls. J Clin Endocrinol Metab 94 (5): 1527–32.

Reichert FF, Menezes AM, Kingdom Wells JC, Ekelund E, Rodrigues FM, Hallal PC (2009) A methodological model for collecting high-quality data on physical activity in developing settings-the experience of the 1993 Pelotas (Brazil) Birth Cohort study. J Phys Act Health 6 (3): 360–6.

Reichert FF, Baptista Menezes AM, Wells JC, Carvalho Dumith S, Hallal PC (2009) Physical activity as a predictor of adolescent body fatness: a systematic review. Sports Med 39 (4): 279–94.

Rosenfeld E, Beyerlein A, Hadders-Algra M, Kennedy K, Singhal A, Fewtrell M, Lucas A, Koletzko B, von Kries R (2009) IPD meta-analysis shows no effect of LC-PUFA supplementation on infant growth at 18 months. Acta Paediatr 98 (1): 91–7.

Siervo M, Wells JC, Cizza G (2009) The contribution of psychosocial stress to the obesity epidemic: an evolutionary approach. Horm Metab Res 41 (4): 261–70.

Singhal A (2009) The early origins of atherosclerosis. Adv Exp Med Biol 646: 51–8.

Wells JC (2009) Ethnic variability in adiposity and cardiovascular risk: the variable disease selection hypothesis. Int J Epidemiol 38 (1): 63–71.

Wells JC (2009) Historical cohort studies and the early origins of disease hypothesis: making sense of the evidence. Proc Nutr Soc 68 (2): 179–88.

Wells JC, Williams JE, Haroun D, Fewtrell MS, Colantuoni A, Siervo M (2009) Aggregate predictions improve accuracy when calculating metabolic variables used to guide treatment. Am J Clin Nutr 89 (2): 491–9.

Bishop N, Braillon P, Burnham J, Cimaz R, Davies J, Fewtrell M, Hogler W, Kennedy K, Mäkitie O, Mughal Z, Shaw N, Vogiatzi M, Ward K, Bianchi ML (2008) Dual-energy X-ray aborptiometry assessment in children and adolescents with diseases that may affect the skeleton: the 2007 ISCD Pediatric Official Positions. J Clin Densitom 11 (1): 29–42.

Chomtho S, Wells JC, Williams JE, Lucas A, Fewtrell MS (2008) Associations between birth weight and later body composition: evidence from the 4-component model. Am J Clin Nutr 88 (4): 1040–8.

Chomtho S, Wells JC, Williams JE, Davies PS, Lucas A, Fewtrell MS (2008) Infant growth and later body composition: evidence from the 4-component model. Am J Clin Nutr 87 (6): 1776–84.

Cole TJ, Fewtrell MS, Prentice A (2008) The fallacy of using percentage body fat as a measure of adiposity. Am J Clin Nutr 87 (6): 1959; author reply 1959–60.

Edmonds CJ, Isaacs EB, Visscher PM, Rogers M, Lanigan J, Singhal A, Lucas A, Gringras P, Denton J, Deary IJ (2008) Inspection time and cognitive abilities in twins aged 7 to 17 years: Age-related changes, heritability and genetic covariance. Intelligence 36: 210–225.

Fewtrell MS, Loh KL, Chomtho S, Kennedy K, Hawdon J, Khakoo A (2008) Quantitative ultrasound (QUS): a useful tool for monitoring bone health in preterm infants?. Acta Paediatr 97 (12): 1625–30.

Fewtrell MS, Benden C, Williams JE, Chomtho S, Ginty F, Nigdikar SV, Jaffe A (2008) Undercarboxylated osteocalcin and bone mass in 8-12 year old children with cystic fibrosis. J Cyst Fibros 7 (4): 307–12.

Fewtrell MS, Kennedy K, Singhal A, Martin RM, Ness A, Hadders-Algra M, Koletzko B, Lucas A (2008) How much loss to follow-up is acceptable in long-term randomised trials and prospective studies?. Arch Dis Child 93 (6): 458–61.

Isaacs EB, Gadian DG, Sabatini S, Chong WK, Quinn BT, Fischl BR, Lucas A (2008) The effect of early human diet on caudate volumes and IQ. Pediatr Res 63 (3): 308–14.

Isaacs E, Oates J, (2008) Nutrition and cognition: assessing cognitive abilities in children and young people. Eur J Nutr 47[Suppl 3]: 4–24.

King C, Fewtrell M (2008) Fishing for brain power?. Arch Dis Child Fetal Neonatal Ed 93 (1): F4–6.

Mattocks C, Ness A, Leary S, Tilling K, Blair SN, Shield J, Deere K, Saunders J, Kirkby J, Smith GD, Wells J, Wareham N, Reilly J, Riddoch C (2008) Use of accelerometers in a large field-based study of children: protocols, design issues, and effects on precision. J Phys Act Health 5 Suppl 1: S98–111.

Mundy HR, Williams JE, Lee PJ, Fewtrell MS (2008) Reduction in bone mineral density in glycogenosis type III may be due to a mixed muscle and bone deficit. J Inherit Metab Dis 31 (3): 418–23.

Neal EG, Chaffe H, Schwartz RH, Lawson MS, Edwards N, Fitzsimmons G, Whitney A, Cross JH (2008) The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial. Lancet Neurol 7 (6): 500–6.

Neal EG, Chaffe HM, Edwards N, Lawson MS, Schwartz RH, Cross JH (2008) Growth of children on classical and medium-chain triglyceride ketogenic diets. Pediatrics 122 (2): e334–40.

Nielsen SB, Wells JC, Fewtrell MS, Reilly JJ (2008) Feeding behaviour and energy balance in 4- to 6-month-old infants: adaptive changes during exclusive breast-feeding. Proc Nutr Soc 67 (OCE): E220.

Schroff RC, Shah V, Hiorns MP, Schoppet M, Hofbauer LC, Hawa G, Schurgers LJ, Singhal A, Merryweather I, Brogan P, Shanahan C, Deanfield J, Rees L (2008) The circulating calcification inhibitors, fetuin-A and osteoprotegerin, but not Matrix Gla protein, are associated with vascualr stiffness and calcification in children on dialysis. Nephrol Dial Translant 23: 3263–3271.

Singhal A, Macfarlane G, Macfarlane S, Lanigan J, Kennedy K, Elias-Jones A, Stephenson T, Dudek P, Lucas A (2008) Dietary nucleotides and fecal microbiota in formula-fed infants: a randomized controlled trial. Am J Clin Nutr 87 (6): 1785–92.

Townsend JL, Craig G, Lawson M, Reilly S, Spitz L (2008) Cost-effectiveness of gastrostomy placement for children with neurodevelopmental disability. Arch Dis Child 93 (10): 873–7.

Wells JC, Ruto A, Treleaven P (2008) Whole-body three-dimensional photonic scanning: a new technique for obesity research and clinical practice. Int J Obes (Lond) 32 (2): 232–8.

Wells JC (2008) Response to Gluckman et al. and Bateson: predictive adaptive responses. Trends Endocrinol Metab 19 (4): 112.

Wells JC, Hallal PC, Reichert FF, Menezes AM, Araújo CL, Victora CG (2008) Sleep patterns and television viewing in relation to obesity and blood pressure: evidence from an adolescent Brazilian birth cohort. Int J Obes (Lond) 32 (7): 1042–9.

Wells JC, Fewtrell MS (2008) Is body composition important for paediatricians?. Arch Dis Child 93: 168–172.

Wells JC, Cole TJ, Bruner D, Treleaven P (2008) Body shape in American and British adults: between-country and inter-ethnic comparisons. Int J Obes (Lond) 32 (1): 152–9.

Wells JC, Cole TJ, Treleaven P (2008) Age-variability in body shape associated with excess weight: the UK National Sizing Survey. Obesity (Silver Spring) 16 (2): 435–41.

Wolman J, Skelly E, Kolotourou M, Lawson M, Sacher P (2008) Tackling toddler obesity through a pilot community-based family intervention. Community Pract 81 (1): 28–31.

Carnielli VP, Simonato M, Verlato G, Luijendijk I, De Curtis M, Sauer PJ, Cogo PE (2007) Synthesis of long-chain polyunsaturated fatty acids in preterm newborns fed formula with long-chain polyunsaturated fatty acids. Am J Clin Nutr 86 (5): 1323–30.

Coelho R, Wells J, Symth J, Semple R, O'rahilly S, Eaton S, Hussain K (2007) Severe Hypoinsulinaemic Hypoglycaemia in a Premature Infant Associated with Poor Weight Gain and Reduced Adipose Tissue. Horm Res 68 (2): 91–98.

Cormack F, Cross JH, Isaacs E, Harkness W, Wright I, Vargha-Khadem F, Baldeweg T (2007) The development of intellectual abilities in pediatric temporal lobe epilepsy. Epilepsia 48 (1): 201–4.

Fewtrell MS, Morgan JB, Duggan C, Gunnlaugsson G, Hibberd PL, Lucas A, Kleinman RE (2007) Optimal duration of exclusive breastfeeding: what is the evidence to support current recommendations?. Am J Clin Nutr 85 (2): 635S–638S.

Fewtrell MS, EARNEST consortium (2007) Session 6: Infant nutrition: future research developments in Europe EARNEST, the early nutrition programming project: EARly Nutrition programming - long-term Efficacy and Safety Trials and integrated epidemiological, genetic, animal, consumer and economic research. Proc Nutr Soc 66 (3): 435–41.

Lanigan J, Turnbull B, Singhal A (2007) Toddler diets in the UK: deficiencies and imbalances. 2. Relationship of toddler diet to later health. J Fam Health Care 17 (6): 197–200.

Ness AR, Leary SD, Mattocks C, Blair SN, Reilly JJ, Wells J, Ingle S, Tilling K, Smith GD, Riddoch C (2007) Objectively Measured Physical Activity and Fat Mass in a Large Cohort of Children. PLoS Med 4 (3): e97.

Ong KK, Northstone K, Wells JC, Rubin C, Ness AR, Golding J, Dunger DB (2007) Earlier Mother's Age at Menarche Predicts Rapid Infancy Growth and Childhood Obesity. PLoS Med 4 (4): e132.

Owino VO, Kasonka LM, Sinkala MM, Wells JK, Eaton S, Darch T, Coward A, Tomkins AM, Filteau SM (2007) Fortified complementary foods with or without {alpha}-amylase treatment increase hemoglobin but do not reduce breast milk intake of 9-mo-old Zambian infants. Am J Clin Nutr 86 (4): 1094–103.

Sacher P, Chadwick P, Kolotourou M, Cole TJ, Lawson M, Singhal A (2007) The MEND RCT: effectiveness on health outcomes in obese children. International Journal of Obesity 31 (Suppl 1): S12.

Singhal A (2007) Does breastfeeding protect from growth acceleration and later obesity?. Nestle Nutr Workshop Ser Pediatr Program 60: 15–25; discussion 25–9.

Singhal A, Lanigan J (2007) Breastfeeding, early growth and later obesity. Obes Rev 8 Suppl 1: 51–4.

Singhal A, Cole TJ, Fewtrell M, Kennedy K, Stephenson T, Elias-Jones A, Lucas A (2007) Promotion of faster weight gain in infants born small for gestational age: is there an adverse effect on later blood pressure?. Circulation 115 (2): 213–20.

Singhal A, Morley R, Cole TJ, Kennedy K, Sonksen P, Isaacs E, Fewtrell M, Elias-Jones A, Stephenson T, Lucas A (2007) Infant nutrition and stereoacuity at age 4-6 y. Am J Clin Nutr 85 (1): 152–9.

Toschke AM, Martin RM, von Kries R, Wells J, Smith GD, Ness AR (2007) Infant feeding method and obesity: body mass index and dual-energy X-ray absorptiometry measurements at 9-10 y of age from the Avon Longitudinal Study of Parents and Children (ALSPAC). Am J Clin Nutr 85 (6): 1578–85.

Turnbull B, Lanigan J, Singhal A (2007) Toddler diets in the U.K.: deficiencies and imbalances. 1. Risk of micronutrient deficiencies. J Fam Health Care 17 (5): 167–70.

Victora CG, Sibbritt D, Horta BL, Lima RC, Cole T, Wells J (2007) Weight gain in childhood and body composition at 18 years of age in Brazilian males. Acta Paediatr 96 (2): 296–300.

Wells JC (2007) Environmental Quality, Developmental Plasticity and the Thrifty Phenotype: A Review of Evolutionary Models. Evol Bioinformat 3: 109–120.

Wells JC, Stock JT (2007) The biology of the colonizing ape. Am J Phys Anthropol Suppl 45: 191–222.

Wells JC, Bilal R, Abbass KA, Latif Z, Roohi S, Hafeez A (2007) Breast-milk intake in exclusively breastfed Pakistani infants: an estimation by deuterium dilution method. Pakistan Paediatrics Journal 13: 111–9.

Wells JC (2007) The programming effects of early growth. Early Hum Dev 83 (12): 743–8.

Wells JC (2007) Flaws in the theory of predictive adaptive responses. Trends Endocrinol Metab 18 (9): 331–7.

Wells JC (2007) Sexual dimorphism of body composition. Best Pract Res Clin Endocrinol Metab 21 (3): 415–30.

Wells JC, Chomtho S, Fewtrell MS (2007) Programming of body composition by early growth and nutrition. Proc Nutr Soc 66 (3): 423–34.

Wells JC (2007) Commentary: Why are South Asians susceptible to central obesity?--the El Nino hypothesis. Int J Epidemiol 36 (1): 226–7.

Wells JC, Treleaven P, Cole TJ (2007) BMI compared with 3-dimensional body shape: the UK National Sizing Survey. Am J Clin Nutr 85 (2): 419–25.

Wells JC (2007) The thrifty phenotype as an adaptive maternal effect. Biol Rev Camb Philos Soc 82 (1): 143–72.

Wells JC, Williams JE, Fewtrell M, Singhal A, Lucas A, Cole TJ (2007) A simplified approach to analysing bio-electrical impedance data in epidemiological surveys. Int J Obes (Lond) 31 (3): 507–14.

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