MRC Centre of Epidemiology for Child Health
Key publications that have come from research conducted either through the centre or in collaboration and using the 1958 birth cohort resource.
The 1958 Cohort is part of a number of research consortia of cohort studies, including:
The EArly Genetics and Lifecourse Epidemiology Consortium
Study of Underlying Genetic Determinants of Vitamin D and Highly Related Traits
The UCL-London-School-Edinburgh-Bristol consortium of population-based prospective studies
Publications for the 1958 Birth Cohort Study
Below are publications of findings and research done using data from the 1958 Birth Cohort and involving scientists from this center.
- Physical activity attenuates the influence of FTO variants on obesity; a meta-analysis of 218,166 adults and 19,268 children. PLoS Medicine 2011 Nov;8(11):e1001116.
- Associations with early life socio-economic position in adult DNA methylation. IJE 2012 Feb;41(1):62-74.
- Changes in Body mass index, duration of overweight and obesity and glucose metabolism: 45 years of follow-up of a birth cohort. Diabetes Care 2011;34:1–6.
- Physical (in)activity over 20y in adulthood: associations with adult lipid levels in the 1958 British birth cohort, Atherosclerosis 2011, doi:10.1016/j.atherosclerosis.2011.07.109.
- Comparative analysis of GWAS signals for lipids, diabetes and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration (CBGC) European Heart Journal 2011; doi: 10.1093/eurheartj/ehr225.
- Genetic variants associated with von Willebrand factor levels in healthy men and women dentified using the HumanCVD BeadChip Annals of Human Genetics.2011 Jul;75(4):456-67.
- Working patterns and vitamin D status in mid-life: a cross-sectional study in the 1958 British birth cohort. Occupational and Environmental Medicine 2011 doi:10.1136/oem.2010.063479.
- Vitamin D status has a linear association with seasonal infections and lung function in British adults. British Journal of Nutrition 2011, 1-8. DOI: 10.1017/S0007114511001991.
- Predicting cardiovascular disease risk factors in mid-adulthood from childhood body mass index: utility of different cut-offs for childhood BMI. Am J Clin Nutr 2011;93:1204-1211 First published ahead of print March 23, 2011 as doi: 10.3945/ajcn.110.001222.
- Absence of association of a SNP in the TERT-CLPTM1L locus with age-related phenotypes in a large multi-cohort study: the HALCyon program. Aging Cell 2011;10:520-32.
- Parental and offspring adiposity associations: insights from the 1958 British birth cohort. Annals Human Biology. 2011;38:390-399.
- Diet, lifestyle and chronic widespread pain: Results from the 1958 British Birth Cohort Study. Pain Research & Management. 2011;16:87-92.
- Repeated exposure to socioeconomic disadvantage and health selection as life course pathways to mid-life depressive and anxiety disorders. Social Psychiatry and Psychiatric Epidemiology 2011;46:549-558.
- Psychological health throughout life and adult cortisol patterns at 45yr. Psychoneuroendocrinology 2010 24th July doi: 10.1016/j.psyneuen.2010.06.010.
- 25-hydroxyvitamin D and pre-clinical alterations in inflammatory and hemostatic markers: a cross sectional analysis in the 1958 British birth cohort PLoS ONE 2010;25-5(5):e10801.
- Do early life exposures explain associations in mid-adulthood between workplace factors and risk factors for cardiovascular disease? IJE, Advance Access January 16, 2010; doi: doi:10.1093/ije/dyp365.
- Associations between parental and offspring adiposity up to mid-life: the contribution of adult lifestyle factors in the 1958 British birth cohort study American Journal of Clinical Nutrition 2010;92:946 - 953.
- Common genetic determinants of vitamin D insufficiency: the SUNLIGHT consortium. Lancet 2010 376:180–88.
- Changing influences on childhood obesity: a study of two generations of the 1958 British Birth Cohort. American Journal of Epidemiology 2010;171:1289–1298.
- Variants at two loci (in ADCY5 and near CCNL1) influence fetal growth and birth weight. Nature Genetics 2010;42: 430-435.
- Maternal smoking in pregnancy, adult adiposity and other risk factors for cardiovascular disease. Atherosclerosis 2010;211:643–648.
- Shift work and risk factors for cardiovascular disease: a study at age 45y in the 1958 British birth cohort. European Journal of Epidemiology 2010;25:305-314.
- Does the influence of childhood adversity on psychopathology persist across the lifecourse? A 45 year prospective epidemiologic study Annals of Epidemiology 2010;20:385–394.
- Childhood hardship, maternal smoking and birth outcomes: a prospective cohort study. Archives of Pediatrics & Adolescent Medicine. 2010;164:533-539.
- Influence of childhood behaviour on the reporting of chronic widespread pain in adulthood: results from the 1958 British Birth Cohort Study. Rheumatology 2010; 49:1882-1888. doi: 10.1093/rheumatology/keq052.
- Foetal environment and early age at natural menopause in a British birth cohort study. Human Reproduction 2010;25:791–798. Advanced Access: January 3, 2010 doi:10.1093/humrep/dep451.
- Childhood cognition and risk factors for cardiovascular disease in mid-adulthood: the 1958 birth cohort study. Am J Public Health 2010;100:129-136.
- Night-work, long working hours, psychosocial work stress and cortisol secretion in mid-life: evidence from a British birth cohort. Occupational and Environmental Medicine 2009 Published Online First: 14 June 2009. doi:10.1136/oem.2008.044396.
- The influence of socioeconomic status on the reporting of regional and widespread musculoskeletal pain: results from the 1958 British Birth Cohort Study. Ann Rheum Dis. 2009; 68: 1591-1995.
- Type 2 Diabetes Risk Alleles are Associated with Reduced Size at Birth. Diabetes 2009, 58:1428–1433.
- Serum 25-hydroxyvitamin D and IgE – a significant but non linear relationship. Allergy 2009 Apr;64(4):613-620.
- Activity patterns in British 45 year olds: Cross-sectional findings from the 1958 British birth cohort. European J Clinical Nutrition 2009;63:978-985. Online publication, February 2009; doi:10.1038/ejcn.2009.6.
- Intergenerational influences on childhood BMI: the effect of parental BMI trajectories. American Journal of Clinical Nutrition 2009 89,1-7.
- Adverse events in childhood and chronic widespread pain in adult life: Results from the 1958 British Birth Cohort Study Pain 2009;143:92–96.
- Gestational age and risk factors for cardiovascular disease: evidence from the 1958 British birth cohort followed to mid-life. IJE 2009 38: 235-244. Advance Access published on July 25, 2008; doi: doi:10.1093/ije/dyn154.
- Vitamin D and chronic widespread pain in a white middle-aged British population: evidence from a cross-sectional population survey. Ann Rheum Dis, 2009;68:817-822. Aug 2008; doi:10.1136/ard.2008.090456.
- Social Differences in Insulin-like Growth Factor-1: Findings from a British Birth Cohort Ann Epidemiol. 2008;18:664-670.
- Co-occurrence of risk factors for cardiovascular disease by social class: 1958 British birth cohort. JECH 2008;62:1030-1035.
- Child-to-adult BMI and height trajectories: a comparison of two British birth cohorts. American Journal of Epidemiology. 2008;168:1008–1015.
- Psychosocial work characteristics and anxiety and depressive disorders in midlife: the effects of prior psychological distress. Occupational and Environmental Medicine. 2008, 65, 634-42 (published online, 3 April).
- Sex differences in the associations between birthweight and lipids in middle-age: Findings from the 1958 British birth cohort. Atherosclerosis 2008;200:141-149
- Childhood and adulthood socioeconomic position and midlife depressive and anxiety disorders. Br J Psych 2008. 192, 152-153.
- Obesity and type 2 diabetes risk in mid adult life: The role of childhood adversity. Pediatrics 2008, 121, e1240-e1249.
- Effects of socioeconomic position on inflammatory and hemostatic markers: A lifecourse analysis in the 1958 British birth cohort. AJE 2008.167(11), 1332-1341.
- Cognitive development in childhood and drinking behaviour over two decades in adulthood. JECH. 2008; 62: p. 506-512. doi:10.1136/jech.2007.059840.
- Lifecourse socioeconomic predictors of midlife drinking patterns, problems and abstention: Findings from the 1958 British Birth Cohort Study. Drug and Alcohol Dependence2008; 95:269–278.
- Cognitive development and cortisol patterns in mid-life: findings from a British birth cohort. Psychoneuroendocrinology 2008; 33: 530–539.
- Is the relation of social class to change in Hearing Threshold Levels from childhood to middle age explained by noise, smoking and drinking behaviour? Int J Audiology 2008; 47:100-108.
- Loss and representativeness in a biomedical survey at age 45 years: 1958 British birth cohort. J Epidemiol Community Health 2008;62;216-223. doi:10.1136/jech.2006.058966.
- Hyppönen E, Boucher B, Berry D, Power C. 25-hydroxyvitamin D, insulin-like growth factor I and metabolic syndrome at age 45y: a cross-sectional study in the 1958 British birth cohort. Diabetes. 2008. 57: 298-305; published online before print as 10.2337/db07-1122.
- Television viewing and obesity: a prospective study in the 1958 British birth cohort. European Journal of Clinical Nutrition. 2008;62:1355-63.
- Is there an association between hysterectomy and subsequent adiposity? Maturitas, 2007; 58: 296-307.
- Serum 25-hydroxyvitamin D measurement in a large population survey with statistical harmonization of assay variation to an international standard. Harmonization of 25(OH)D in a large survey. J Clin Endocrinol Metab Dec 2007; 92: 4615 - 4622.
- Early life influences on adult leg and trunk length in the 1958 British birth cohort. American Journal Human Biology 2007, 19: 836-43.
- Body Mass Index throughout the life-course and blood pressure in mid-adult life: a birth cohort study. Journal of Hypertension 2007, 25:1215–1223.
- Lifecourse influences on health among British adults: effects of region of residence in childhood and adulthood. IJE 2007;36: 522-531.
- Lifecourse influences on health in British adults: effects of socio-economic position in childhood and adulthood. IJE, 2007;36: 532-539.
- Atherton K, Power C. Health inequalities with the National Statistics-Socioeconomic classification: disease risk factors and health in the 1958 British birth cohort European Journal of Public Health 2007, 17, No. 5, 486–491.
- Life-time socio-economic position and cortisol patterns in mid-life. Psychoneuroendocrinology 2007; 32 (issue 7); 824-833.
- Prenatal exposures and glucose metabolism in adulthood: are effects mediated through birthweight and adiposity? Diabetes Care. 2007, 30: 918-24.
- Hypovitaminosis D in British adults at age 45y: nationwide cohort study on dietary and lifestyle determinants. American Journal of Clinical Nutrition 2007, 85, 860-8
- Are common symptoms in childhood associated with chronic widespread body pain in adulthood? Results from the 1958 British Birth Cohort Study. Arthritis and Rheumatism 2007, 56, 1669-1675.
- Childhood and adulthood psychological ill-health as predictors of mid-life affective and anxiety disorders: the 1958 British Birth Cohort. Archives of General Psychiatry 2007, 64:668-678.
- Type 2 diabetes TCF7L2 risk genotypes alter birth weight: a study of 24,053 individuals. Am J Human Genetics 2007.
- Diabetes risk in British adults in mid-life: a national prevalence study of glycated haemoglobin. Diabetic Medicine. 2007, 24:317-21.
- Drinking histories of self-identified lifetime abstainers and occasional drinkers: Findings from the 1958 British Birth Cohort Study. Alcohol and Alcoholism. 2006, 41, 650-654.
- Patterns of growth from birth to adulthood, adiposity and cortisol patterns in mid-adulthood. Journal of Clinical Endocrinology & Metabolism. 2006, 91, 4264- 4270.
- Vitamin D status and glucose homeostasis in the 1958 British birth cohort: the role of obesity. Diabetes Care 2006, 29:2244-6.
- Type 2 diabetes in midlife estimated from the Cambridge Risk Score and BMI. Archives of Internal Medicine 2006, 166(6):682-8.
- Longitudinal physical activity and diet patterns in the 1958 British birth cohort. Medicine & Science in Sports & Exercise, 2006;38(3):547-54.
- Physical activity and change in body mass index from adolescence to mid-adulthood in the 1958 British cohort. IJE, 2006, 35, 197-204.
- Physical activity, television viewing and body mass index: a cross sectional analysis from childhood to adulthood in the 1958 British cohort. IJO, 2005; 29, 1212-1221.
- An intergenerational and lifecourse study of health and mortality risk in parents of the 1958 birth cohort (I): Methods and tracing. Public Health 2005;119, 599-607.
- An intergenerational and lifecourse study of health and mortality risk in parents of the 1958 birth cohort (II): Mortality rates and study representativeness. Public Health 2005; 119, 608-615.
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