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Recent publications

Abubakar I, Laundy MT, French CE, Shingadia D (2008) Epidemiology and treatment outcome of childhood tuberculosis in England and Wales: 1999-2006. Arch Dis Child 93 (12): 1017–21.

Ackland GL, Gutierrez Del Arroyo A, Yao ST, Stephens RC, Dyson A, Klein NJ, Singer M, Gourine AV (2010) Low-molecular-weight polyethylene glycol improves survival in experimental sepsis. Crit Care Med 38 (2): 629–36.

Adalat S, Paliwalla M, Novelli V, Riordan F A (2008) A survey of tuberculosis services in the UK. Arch Dis ChildArchives of disease in childhood 93: 575–7.

Agbeko RS, Fidler KJ, Allen ML, Wilson P, Klein NJ, Peters MJ (2010) Genetic variability in complement activation modulates the systemic inflammatory response syndrome in children. Pediatr Crit Care Med 11 (5): 561-7.
Agbeko RS, Holloway JW, Allen ML, Ye S, Fidler KJ, Pappachan J, Goldman A, Pontefract D, Deanfield J, Klein NJ, Peters MJ (2010) Genetic polymorphisms in the endotoxin receptor may influence platelet count as part of the acute phase response in critically ill children. Intensive Care Medicine 36 (6): 1023-1032.

Agius E, Lacy KE, Vukmanovic-Stejic M, Jagger AL, Papageorgiou AP, Hall S, Reed JR, Curnow SJ, Fuentes-Duculan J, Buckley CD, Salmon M, Taams LS, Krueger J, Greenwood J, Klein N, Rustin MH, Akbar AN (2009) Decreased TNF-alpha synthesis by macrophages restricts cutaneous immunosurveillance by memory CD4+ T cells during aging. J Exp Med 206 (9): 1929–40.

Al-Adnani M, Williams S, Anderson J, Ashworth M, Malone M, Sebire NJ (2007) Immunohistochemical nuclear positivity for wt1 in childhood acute myeloid leukemia. Fetal Pediatr Pathol 26 (4): 193–7.

American Academy of Pediatrics Committee on Pediatric AIDS, Section on International Child Health, Havens PL, Gibb DM (2007) Increasing antiretroviral drug access for children with HIV infection. Pediatrics 119 (4): 838–45.

Anthony L, Meehan A, Amos B, Mtove G, Mjema J, Malahiyo R, Yin JK, Oftadeh S, Gilbert GL, Shingadia D, et al.: Nasopharyngeal carriage of Streptococcus pneumoniae: prevalence and risk factors in HIV-positive children in Tanzania. Int J Infect Dis 2012, 16:e753-757.

Arulkumaran N, Jawad S, Smith SW, Harper L, Brogan P, Pusey CD, Salama AD (2011) Long- term outcome of paediatric patients with ANCA vasculitis. Pediatr Rheumatol Online J 9(1): 12.

Azizia M, Lloyd J, Allen M, Klein N, Peebles D (2012) Immune status in very preterm neonates. Pediatrics 129(4): e967-74.

Babiker A, Castro nGH, Compagnucci A, Fiscus S, Giaquinto C, Gibb DM, Harper L, Harrison L, Hughes M, McKinney R, Melvin A, Mofenson L, Saidi Y, Smith ME, Tudor-Williams G, Walker AS (2011) First-line antiretroviral therapy with a protease inhibitor versus non-nucleoside reverse transcriptase inhibitor and switch at higher versus low viral load in HIV-infected children: an open-label, randomised phase 2/3 trial. Lancet Infect Dis 11(4): 273-83.

Bai L, Schüller S, Whale A, Mousnier A, Marches O, Wang L, Ooka T, Heuschkel R, Torrente F, Kaper JB, Gomes TA, Xu J, Phillips AD, Frankel G (2008) Enteropathogenic Escherichia coli O125:H6 triggers attaching and effacing lesions on human intestinal biopsy specimens independently of Nck and TccP/TccP2. Infect Immun 76 (1): 361–8.

Bamford AR, Crook AM, Clark JE, Nademi Z, Dixon G, Paton JY, Riddell A, Drobniewski F, Riordan A, Anderson ST, Williams A, Walters S, Kampmann B (2010) Comparison of interferon-{gamma} release assays and tuberculin skin test in predicting active tuberculosis (TB) in children in the UK: a paediatric TB network study.
Arch Dis Child 95(3):180-6.

Barker CI, Standing JF, Turner MA, McElnay JC, Sharland M (2012) Antibiotic dosing in children in Europe: can we grade the evidence from pharmacokinetic/pharmacodynamic studies - and when is enough data enough? Curr Opin Infect Dis 25(3): 235-42.

Basu N, Watts R, Bajema I, Baslund B, Bley T, Boers M, Brogan P, Calabrese L, Cid MC, Cohen-Tervaert JW, Flores-Suarez LF, Fujimoto S, de Groot K, Guillevin L, Hatemi G, Hauser T, Jayne D, Jennette C, Kallenberg CG, Kobayashi S, Little MA, Mahr A, McLaren J, Merkel PA, Ozen S, Puechal X, Rasmussen N, Salama A, Salvarani C, Savage C, Scott DG, Segelmark M, Specks U, Sunderköetter C, Suzuki K, Tesar V, Wiik A, Yazici H, Luqmani R (2010) EULAR points to consider in the development of classification and diagnostic criteria in systemic vasculitis. Ann Rheum Dis 69 (10): 1744-50.

Baxendale HE, Johnson M, Stephens RC, Yuste J, Klein N, Brown JS, Goldblatt D (2008) Natural human antibodies to pneumococcus have distinctive molecular characteristics and protect against pneumococcal disease. Clin Exp Immunol 151 (1): 51–60.

Behjati S, Zilbauer M, Heuschkel R, Phillips A, Salvestrini C, Torrente F, Bates AW (2009) Defining eosinophilic colitis in children: insights from a retrospective case series. J Pediatr Gastroenterol Nutr 49 (2): 208–15.

Benden C, Harpur-Sinclair O, Ranasinghe AS, Hartley JC, Elliott MJ, Aurora P (2007) Surveillance bronchoscopy in children during the first year after lung transplantation: Is it worth it?. Thorax 62 (1): 57–61.

Bhutta ZA, Nelson EA, Lee WS, Tarr PI, Zablah R, Phua KB, Lindley K, Bass D, Phillips A, Persistent Diarrhea Working Group (2008) Recent advances and evidence gaps in persistent diarrhea. J Pediatr Gastroenterol Nutr 47 (2): 260–5.

Bishay M, Retrosi G, Horn V, Cloutman-Green E, Harris K, de CP, Klein N, Eaton S, Pierro A (2012) Septicaemia due to enteric organisms is a later event in surgical infants requiring parenteral nutrition. Eur J Pediatr Surg 22(1): 50-3.

Bishay M, Retrosi G, Horn V, Cloutman-Green E, Harris K, De CP, Klein N, Eaton S, Pierro A (2011) Chlorhexidine antisepsis significantly reduces the incidence of sepsis and septicemia during parenteral nutrition in surgical infants. J Pediatr Surg 46(6): 1064-9.

Blauwendraat C, Dixon GL, Hartley JC, Foweraker J, Harris KA (2012) The use of a two-gene sequencing approach to accurately distinguish between the species within the Mycobacterium abscessus complex and Mycobacterium chelonae. Eur J Clin Microbiol Infect Dis 31:1847-1853.

Booy R, El Bashir H, Rashid H, Shingadia D, Haworth E (2009) Influenza and meningococcal disease: lessons for travellers and government from 2 epidemic diseases. Travel Med Infect Dis 7 (4): 253–6.

Boulter EL, Eleftheriou D, Sebire NJ, Edelsten C, Brogan PA (2012) Inflammatory lesions of the orbit: a single paediatric rheumatology centre experience. Rheumatology (Oxford) 2012; 51(6): 1070-5.

Brierley J, Highe L, Hines S, Dixon G (2012) Reducing VAP by instituting a care bundle using improvement methodology in a UK Paediatric Intensive Care Unit. Eur J Pediatr 171(2): 323-30.

Brogan K, Eleftheriou D, Rajput K, Edelsten C, Sebire NJ, Brogan PA (2012) Tubulointerstitial nephritis, uveitis, hearing loss and vestibular failure: TINU-atypical Cogan's overlap syndrome. Rheumatology (Oxford) 51(5): 950-2.

Brogan P, Eleftheriou D, Dillon M (2010) Small vessel vasculitis. Pediatr Nephrol 25 (6): 1025–35.

Brogan PA (2007) What's new in the aetiopathogenesis of vasculitis?. Pediatr Nephrol 22 (8): 1083–94.

Brogan PA, Shah V, Clarke LA, Dillon MJ, Klein N (2008) T cell activation profiles in Kawasaki syndrome. Clin Exp Immunol 151 (2): 267–74.

Brogan RJ, Eleftheriou D, Gnanapragasam J, Klein NJ, Brogan PA (2009) Infliximab for the treatment of intravenous immunoglobulin resistant Kawasaki disease complicated by coronary artery aneurysms: a case report. Pediatr Rheumatol Online J 7 (1): 3.

Bunupuradah T, Duong T, Compagnucci A, McMaster P, Bernardi S, Kanjanavanit S, Rampon O, Faye A, Saidi Y, Riault Y, de Rossi A, Klein N, Ananworanich J, Gibb D (2012) Outcomes after reinitiating antiretroviral therapy in children randomized to planned treatment interruptions in the PENTA 11 Study. AIDS E-Pub

Burger D, Ewings F, Kabamba D, L'homme R, Mulenga V, Kankasa C, Thomason M, Gibb DM, Chintu C, Walker AS (2010) Limited sampling models to predict the pharmacokinetics of nevirapine, stavudine, and lamivudine in HIV-infected children treated with pediatric fixed-dose combination tablets. Ther Drug Monit 32(3): 369-72.

Burger DM, Verweel G, Rakhmanina N, Verwey-Van Wissen CP, La Porte CJ, Bergshoeff AS, Lyall H, Hartwig NG, Green H, Soldin S, Gibb DM, de Groot R (2007) Age-dependent pharmacokinetics of lamivudine in HIV-infected children. Clin Pharmacol Ther 81 (4): 517–20.

Burgner D, Davila S, Breunis WB, Ng SB, Li Y, Bonnard C, Ling L, Wright VJ, Thalamuthu A, Odam M, Shimizu C, Burns JC, Levin M, Kuijpers TW, Hibberd ML, International Kawasaki Disease Genetics Consortium (2009) A genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease. PLoS Genet 5 (1): e1000319.

Burman W J, Cotton M F, Gibb D M, Walker A S, Vernon A A, Donald P R (2008) Ensuring the involvement of children in the evaluation of new tuberculosis treatment regimens. PLoS MedPLoS medicine 5: e176.

Caldwell DM, Gibb DM, Ades AE (2007) Validity of indirect comparisons in meta-analysis. Lancet 369 (9558): 270; author reply 271.

Castro H, Judd A, Gibb DM, Butler K, Lodwick RK, van SA, Ramos JT, Warsawski J, Thorne C, Noguera-Julian A, Obel N, Costagliola D, Tookey PA, Colin C, Kjaer J, Grarup J, Chene G, Phillips A (2011) Risk of triple-class virological failure in children with HIV: a retrospective cohort study. Lancet 377(9777): 1580-7.

Chakraborty R, Smith CJ, Dunn D, Green H, Duong T, Doerholt K, Riordon A, Lyall H, Tookey P, Butler K, Sabin CA, Gibb D, Pillay D, Collaborative HIV Paediatric Study, UK Collaborative Group on HIV Drug Resistance (2008) HIV-1 drug resistance in HIV-1-infected children in the United Kingdom from 1998 to 2004. Pediatr Infect Dis J 27 (5): 457–9.

Charakida M, Donald AE, Leary S, Halcox JP, Turner MW, Johnson M, Loukogeorgakis SP, Okorie MI, Davey Smith G, Deanfield JE, Klein NJ (2010) Endothelial response to childhood infection: the role of mannose-binding lectin (MBL). Atherosclerosis 208 (1): 217–21.

Charakida M, Loukogeorgakis SP, Okorie MI, Masi S, Halcox JP, Deanfield JE, Klein NJ (2009) Increased arterial stiffness in HIV-infected children: risk factors and antiretroviral therapy. Antivir Ther 14 (8): 1075–9.

Chatziandreou I, Gilmour KC, McNicol AM, Costabile M, Sinclair J, Cubitt D, Campbell JD, Kinnon C, Qasim W, Gaspar HB (2007) Capture and generation of adenovirus specific T cells for adoptive immunotherapy. Br J Haematol 136 (1): 117–26.

Chimalapati S, Cohen JM, Brown JS (2012) Cross-protective immunity against heterologous S. pneumoniae. Infect Immun 80: 1946.

Chimalapati S, Cohen JM, Camberlein E, MacDonald N, Durmort C, Vernet T, Hermans PWM, Mitchell T, Brown JS (2012) Effects of deletion of the Streptococcus pneumoniae lipoprotein diacylglycerol transferase gene lgt on ABC transporter function and on growth in vivo. PLoS One 7:e41393.

Chimalapati S, Cohen J, Camberlein E, Durmort C, Baxendale H, de Vogel C, van Belkum A, Brown JS (2011) Infection with conditionally virulent Streptococcus pneumoniae ∆pab bacteria induces antibody to conserved protein antigens but does not protect against systemic infection with heterologous strains. Infect Immun  79(12): 4965-76.

Chong Y, Fitzhenry R, Heuschkel R, Torrente F, Frankel G, Phillips AD (2007) Human intestinal tissue tropism in Escherichia coli O157 : H7--initial colonization of terminal ileum and Peyer's patches and minimal colonic adhesion ex vivo. Microbiology 153 (Pt 3): 794–802.

Choudhry N, Bajaj-Elliott M, McDonald V (2008) The terminal sialic acid of glycoconjugates on the surface of intestinal epithelial cells activates excystation of Cryptosporidium parvum. Infect Immun 76 (8): 3735–41.

Choudhry N, Korbel DS, Edwards LA, Bajaj-Elliott M, McDonald V (2009) Dysregulation of interferon-gamma-mediated signalling pathway in intestinal epithelial cells by Cryptosporidium parvum infection. Cell Microbiol 11 (9): 1354–64.

Choudhry N, Korbel DS, Zaalouk TK, Blanshard C, Bajaj-Elliott M, McDonald V (2009) Interferon-gamma-mediated activation of enterocytes in immunological control of Encephalitozoon intestinalis infection. Parasite Immunol 31 (1): 2–9.

Clarke LA, Shah V, Arrigoni F, Eleftheriou D, Hong Y, Halcox J, Klein N, Brogan PA (2008) Quantitative detection of circulating endothelial cells in vasculitis: comparison of flow cytometry and immunomagnetic bead extraction. J Thromb Haemost 6 (6): 1025–32.

Clarke LA, Hong Y, Eleftheriou D, Shah V, Arrigoni F, Klein NJ, Brogan PA (2010) Endothelial injury and repair in systemic vasculitis of the young. Arthritis Rheum 62(6): 1770-80.

Cohen JM, Chimalapati S, de VC, van BA, Baxendale HE, Brown JS (2012) Contributions of capsule, lipoproteins and duration of colonisation towards the protective immunity of prior Streptococcus pneumoniae nasopharyngeal colonisation. Vaccine 30(30): 4453-9.

Cohen JM, Chimalapati S, Camberlein EH, Hyams C, Baxendale HE, Brown JS (2011) Protective contributions against invasive Streptococcus pneumoniae pneumonia of antibody and Th17-cell responses to nasopharyngeal colonisation. PLoS One  6(10): e25558.

Cohen JM, Cooper N, Chakrabarti S, Thomson K, Samarasinghe S, Cubitt D, Lloyd C, Woolfrey A, Veys P, Amrolia PJ (2007) EBV-related disease following haematopoietic stem cell transplantation with reduced intensity conditioning. Leuk Lymphoma 48 (2): 256–69.

Cohen JM, Sebire NJ, Harvey J, Gaspar HB, Cathy C, Jones A, Rao K, Cubitt D, Amrolia PJ, Davies EG, Veys P (2007) Successful treatment of lymphoproliferative disease complicating primary immunodeficiency/immunodysregulatory disorders with reduced-intensity allogeneic stem-cell transplantation. Blood 110 (6): 2209–14.

Cortina-Borja M, Williams D, Cubitt WD, Tookey PA, Newell ML, Peckham CS (2007) HIV-1 subtypes in pregnant women in the UK. Int J STD AIDS 18 (3): 160–2.

Crepin VF, Girard F, Schüller S, Phillips AD, Mousnier A, Frankel G (2010) Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo. Mol Microbiol 75 (2): 308–23.

Cressey TR, Green H, Khoo S, Treluyer JM, Compagnucci A, Saidi Y, Lallemant M, Gibb DM, Burger DM, Paediatric European Network for Treatment of AIDS II Study Group (2008) Plasma drug concentrations and virologic evaluations after stopping treatment with nonnucleoside reverse-transcriptase inhibitors in HIV type 1-infected children. Clin Infect Dis 46 (10): 1601–8.

DART Trial Team, Mugyenyi P, Walker AS, Hakim J, Munderi P, Gibb DM, Kityo C, Reid A, Grosskurth H, Darbyshire JH, Ssali F, Bray D, Katabira E, Babiker AG, Gilks CF, Grosskurth H, Munderi P, Kabuye G, Nsibambi D, Kasirye R, Zalwango E, Nakazibwe M, Kikaire B, Nassuna G, Massa R, Fadhiru K, Namyalo M, Zalwango A, Generous L, Khauka P, Rutikarayo N, Nakahima W, Mugisha A, Todd J, Levin J, Muyingo S, Ruberantwari A, Kaleebu P, Yirrell D, Ndembi N, Lyagoba F, Hughes P, Aber M, Lara AM, Foster S, Amurwon J, Wakholi BN, Whitworth J, Wangati K, Amuron B, Kajungu D, Nakiyingi J, Omony W, Fadhiru K, Nsibambi D, Khauka P, Mugyenyi P, Kityo C, Ssali F, Tumukunde D, Otim T, Kabanda J, Musana H, Akao J, Kyomugisha H, Byamukama A, Sabiiti J, Komugyena J, Wavamunno P, Mukiibi S, Drasiku A, Byaruhanga R, Labeja O, Katundu P, Tugume S, Awio P, Namazzi A, Bakeinyaga GT, Katabira H, Abaine D, Tukamushaba J, Anywar W, Ojiambo W, Angweng E, Murungi S, Haguma W, Atwiine S, Kigozi J, Namale L, Mukose A, Mulindwa G, Atwiine D, Muhwezi A, Nimwesiga E, Barungi G, Takubwa J, Murungi S, Mwebesa D, Kagina G, Mulindwa M, Ahimbisibwe F, Mwesigwa P, Akuma S, Zawedde C, Nyiraguhirwa D, Tumusiime C, Bagaya L, Namara W, Kigozi J, Karungi J, Kankunda R, Enzama R, Latif A, Hakim J, Robertson V, Reid A, Chidziva E, Bulaya-Tembo R, Musoro G, Taziwa F, Chimbetete C, Chakonza L, Mawora A, Muvirimi C, Tinago G, Svovanapasis P, Simango M, Chirema O, Machingura J, Mutsai S, Phiri M, Bafana T, Chirara M, Muchabaiwa L, Muzambi M, Mutowo J, Chivhunga T, Chigwedere E, Pascoe M, Warambwa C, Zengeza E, Mapinge F, Makota S, Jamu A, Ngorima N, Chirairo H, Chitsungo S, Chimanzi J, Maweni C, Warara R, Matongo M, Mudzingwa S, Jangano M, Moyo K, Vere L, Mdege N, Machingura I, Katabira E, Ronald A, Kambungu A, Lutwama F, Mambule I, Nanfuka A, Walusimbi J, Nabankema E, Nalumenya R, Namuli T, Kulume R, Namata I, Nyachwo L, Florence A, Kusiima A, Lubwama E, Nairuba R, Oketta F, Buluma E, Waita R, Ojiambo H, Sadik F, Wanyama J, Nabongo P, Oyugi J, Sematala F, Muganzi A, Twijukye C, Byakwaga H, Ochai R, Muhweezi D, Coutinho A, Etukoit B, Gilks C, Boocock K, Puddephatt C, Grundy C, Bohannon J, Winogron D, Gibb DM, Burke A, Bray D, Babiker A, Walker AS, Wilkes H, Rauchenberger M, Sheehan S, Spencer-Drake C, Taylor K, Spyer M, Ferrier A, Naidoo B, Dunn D, Goodall R, Darbyshire JH, Peto L, Nanfuka R, Mufuka-Kapuya C, Kaleebu P, Pillay D, Robertson V, Yirrell D, Tugume S, Chirara M, Katundu P, Ndembi N, Lyagoba F, Dunn D, Goodall R, McCormick A, Lara AM, Foster S, Amurwon J, Wakholi BN, Kigozi J, Muchabaiwa L, Muzambi M, Weller I, Babiker A, Bahendeka S, Bassett M, Wapakhabulo AC, Darbyshire JH, Gazzard B, Gilks C, Grosskurth H, Hakim J, Latif A, Mapuchere C, Mugurungi O, Mugyenyi P, Burke C, Jones S, Newland C, Pearce G, Rahim S, Rooney J, Smith M, Snowden W, Steens JM, Breckenridge A, McLaren A, Hill C, Matenga J, Pozniak A, Serwadda D, Peto T, Palfreeman A, Borok M, Katabira E (2010) Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial. Lancet 375 (9709): 123–31.

de Gaudio M, Moshal K, Malone M, Novelli V (2010) Kikuchi-Fujimoto disease causing fever of unknown origin in a nine-year-old boy. Scand J Infect Dis 42 (11-12): 946-9

Dhaliwal W, Kelly P, Bajaj-Elliott M (2009) Differential effects of Staphylococcal enterotoxin B-mediated immune activation on intestinal defensins. Clin Exp Immunol 156 (2): 263–70.

Dillon MJ, Eleftheriou D, Brogan PA (2010) Medium-size-vessel vasculitis. Pediatr Nephrol 25 (9): 1641-52.

Dixon G, Booth C, Price E, Westran R, Turner M, Klein N (2010) Part of beneficial host response?. BMJ 340: c450.

Dolezalova P, Price-Kuehne FE, Ozen S, Benseler SM, Cabral DA, Anton J, Brunner J, Cimaz R, O'Neil KM, Wallace CA, et al.: Disease activity assessment in childhood vasculitis: development and preliminary validation of the Paediatric Vasculitis Activity Score (PVAS). Ann Rheum Dis 2012.

Dommett R, Chisholm J, Turner M, Bajaj-Elliott M, Klein NJ (2013) Mannose-binding Lectin Genotype Influences Frequency and Duration of Infectious Complications in Children With Malignancy. J Pediatr Hematol Oncol 35:69-75

Dommett R, Geary J, Freeman S, Hartley J, Sharland M, Davidson A, Tulloh R, Taj M, Stoneham S, Chisholm JC (2009) Successful introduction and audit of a step-down oral antibiotic strategy for low risk paediatric febrile neutropaenia in a UK, multicentre, shared care setting. Eur J Cancer 45 (16): 2843–9.

Donegan KL, Walker AS, Dunn D, Judd A, Pillay D, Menson E, Lyall H, Tudor-Williams G, Gibb DM (2012) The prevalence of darunavir-associated mutations in HIV-1-infected children in the UK. Antivir Ther 17(4): 599-603.

Donegan K, Doerholt K, Judd A, Lyall H, Menson E, Butler K, Tookey P, Riordan A, Shingadia D, Tudor-Williams G, Gibb DM, Walker AS (2013) Lopinavir Dosing in HIV-Infected Children in the United Kingdom and Ireland. Pediatr Infect Dis J 32:45-50

Dunn D, Woodburn P, Duong T, Peto J, Phillips A, Gibb D, Porter K, HIV Paediatric Prognostic Markers Collaborative Study (HPPMCS), Concerted Action on Sero-Conversion to AIDS and Death in Europe (CASCADE) Collaboration (2008) Current CD4 cell count and the short-term risk of AIDS and death before the availability of effective antiretroviral therapy in HIV-infected children and adults. J Infect Dis 197 (3): 398–404.

Dzwonek AB, Neth OW, Thiébaut R, Gulczynska E, Chilton M, Hellwig T, Bajaj-Elliott M, Hawdon J, Klein NJ (2008) The role of mannose-binding lectin in susceptibility to infection in preterm neonates. Pediatr Res 63 (6): 680–5.

Dzwonek AB, Novelli V, Schwenk A (2007) Serum leptin concentrations and fat redistribution in HIV-1-infected children on highly active antiretroviral therapy. HIV Med 8 (7): 433–8.

Edwards LA, Bajaj-Elliott M, Klein NJ, Murch SH, Phillips AD (2011) Bacterial-epithelial contact is a key determinant of host innate immune responses to enteropathogenic and enteroaggregative Escherichia coli. PLoS One 6(10): e27030.

Edwards LA, Lucas M, Edwards EA, Torrente F, Heuschkel RB, Klein NJ, Murch SH, Bajaj-Elliott M, Phillips AD (2010) Aberrant response to commensal Bacteroides thetaiotaomicron in Crohn's disease: An ex vivo human organ culture study. Inflamm Bowel Dis 17(5): 1201-8.

Edwards LA, Nistala K, Mills DC, Stephenson HN, Zilbauer M, Wren BW, Dorrell N, Lindley KJ, Wedderburn LR, Bajaj-Elliott M (2010) Delineation of the innate and adaptive T-cell immune outcome in the human host in response to Campylobacter jejuni infection. PLoS One 5 (11): e15398.

Eisen S, Honywood L, Shingadia D, Novelli V (2012) Spinal tuberculosis in children. Arch Dis Child. 97:724-729.

Eleftheriou D, Ganesan V, Hong Y, Klein NJ, Brogan PA (2012) Endothelial injury in childhood stroke with cerebral arteriopathy: A cross-sectional study. Neurology 79:2089-2096

Eleftheriou D, Hong Y, Klein NJ, Brogan PA (2011) Thromboembolic disease in systemic vasculitis is associated with enhanced microparticle-mediated thrombin generation. J Thromb Haemost 9 (9):1864-7

Eleftheriou D, Cox T, Saunders D, Klein NJ, Brogan PA, Ganesan V (2010) Investigation of childhood central nervous system vasculitis: magnetic resonance angiography versus catheter cerebral angiography. Dev Med Child Neurol 52 (9): 863-7.

Eleftheriou D, Gerschman T, Sebire N, Woo P, Pilkington CA, Brogan PA (2010) Biologic therapy in refractory chronic non-bacterial osteomyelitis of childhood. Rheumatology 49 (8): 1505-12.

Eleftheriou D, Amin T, Hook C E, Auchterlonie I, Houlsby W T, Denison A, Rosendhal K, Davidson J E, Klein N, Brogan P A (2008) Castleman's disease in childhood: a surgically curable mimic of autoimmune disease. Rheumatology (Oxford)Rheumatology (Oxford, England) 47: 1435–6.

Eleftheriou D, Brogan PA (2009) Vasculitis in children. Best Pract Res Clin Rheumatol 23 (3): 309–23.

Eleftheriou D, Dillon MJ, Brogan PA (2009) Advances in childhood vasculitis. Curr Opin Rheumatol 21 (4): 411–8.

Eleftheriou D, Melo M, Marks SD, Tullus K, Sills J, Cleary G, Dolezalova P, Ozen S, Pilkington C, Woo P, Klein N, Dillon MJ, Brogan PA (2009) Biologic therapy in primary systemic vasculitis of the young. Rheumatology (Oxford) 48 (8): 978–86.

Ellis JC, L'homme RF, Ewings FM, Mulenga V, Bell F, Chileshe R, Molyneux E, Abernethy J, van Oosterhout JJ, Chintu C, Walker AS, Gibb DM, Burger DM (2007) Nevirapine concentrations in HIV-infected children treated with divided fixed-dose combination antiretroviral tablets in Malawi and Zambia. Antivir Ther 12 (2): 253–60.

Elmi A, Watson E, Sandu P, Gundogdu O, Mills DC, Inglis NF, Manson E, Imrie L, Bajaj-Elliott M, Wren BW, Smith DG, Dorrell N (2012) Campylobacter jejuni outer membrane vesicles play an important role in bacterial interactions with human intestinal epithelial cells. Infect Immun 80:4089-4098.

Fabbri-Arrigoni FI, Clarke L, Wang G, Charakida M, Ellins E, Halliday N, Brogan PA, Deanfield JE, Halcox JP, Klein N (2012) Levels of circulating endothelial cells and colony-forming units are influenced by age and dyslipidemia. Pediatr Res. 72:299-304.

Falcetti E, Hall SM, Phillips PG, Patel J, Morrell NW, Haworth SG, Clapp LH (2010) Smooth muscle proliferation and role of the prostacyclin (IP) receptor in idiopathic pulmonary arterial hypertension. Am J Respir Crit Care Med 182 (9): 1161-70.

Fasano A, Araya M, Bhatnagar S, Cameron D, Catassi C, Dirks M, Mearin ML, Ortigosa L, Phillips A, Celiac Disease Working Group (2008) Federation of International Societies of Pediatric Gastroenterology, Hepatology, and Nutrition Consensus report on celiac disease. J Pediatr Gastroenterol Nutr 47 (2): 214–9.

Felsenstein S, Williams B, Shingadia D, Coxon L, Riordan A, Demetriades AK, Chandler CL, Bassi S, Koutoumanou E, Stapleton S, Sharland M, Bryant PA: Clinical and Microbiologic Features Guiding Treatment Recommendations for Brain Abscesses in Children. Pediatr Infect Dis J 2012.

Ferrand RA, Trigg C, Bandason T, Ndhlovu CE, Mungofa S, Nathoo K, Gibb DM, Cowan FM, Corbett EL (2011) Perception of risk of vertically acquired HIV infection and acceptability of provider-initiated testing and counseling among adolescents in Zimbabwe. Am J Public Health 101(12): 2325-32.

Ferrand RA, Munaiwa L, Matsekete J, Bandason T, Nathoo K, Ndhlovu CE, Munyati S, Cowan FM, Gibb DM, Corbett EL (2010) Undiagnosed HIV infection among adolescents seeking primary health care in Zimbabwe. Clin Infect Dis 51 (7): 844-51.

Ferrand RA, Bandason T, Musvaire P, Larke N, Nathoo K, Mujuru H, Ndhlovu CE, Munyati S, Cowan FM, Gibb DM, Corbett EL (2010) Causes of acute hospitalization in adolescence: burden and spectrum of HIV-related morbidity in a country with an early-onset and severe HIV epidemic: a prospective survey. PLoS Med 7 (2): e1000178.

Ferrand RA, Weiss HA, Nathoo K, Ndhlovu CE, Mungofa S, Munyati S, Bandason T, Gibb DM, Corbett EL (2011) A primary care level algorithm for identifying HIV-infected adolescents in populations at high risk through mother-to-child transmission. Trop Med Int Health 16 (3): 349-55.

Fidler KJ, Hilliard TN, Bush A, Johnson M, Geddes DM, Turner MW, Alton EW, Klein NJ, Davies JC (2009) Mannose-binding lectin is present in the infected airway: a possible pulmonary defence mechanism. Thorax 64 (2): 150–5.

Fillekes Q, Mulenga V, Kabamba D, Kankasa C, Thomason MJ, Cook A, Ferrier A, Chintu C, Walker AS, Gibb DM, Burger DM (2012) Pharmacokinetics of nevirapine in HIV-infected 3-<6 kg infants taking paediatric fixed dose combination tablets. Aids 26:1795-1800.

Fillekes Q, Natukunda E, Balungi J, Kendall L, Bwakura-Dangarembizi M, Keishanyu R, Ferrier A, Lutakome J, Gibb DM, Burger DM, Walker AS (2011) Pediatric under-dosing of efavirenz: a pharmacokinetic study in Uganda. J Acquir Immune Defic Syndr 58(4): 392-8.

Foster C, Judd A, Tookey P, Tudor-Williams G, Dunn D, Shingadia D, Butler K, Sharland M, Gibb D, Lyall H, Collaborative HIV Paediatric Study (CHIPS) (2009) Young people in the United Kingdom and Ireland with perinatally acquired HIV: the pediatric legacy for adult services. AIDS Patient Care STDS 23 (3): 159–66.

Foster C, Lyall H, Olmscheid B, Pearce G, Zhang S, Gibb DM (2009) Tenofovir disoproxil fumarate in pregnancy and prevention of mother-to-child transmission of HIV-1: is it time to move on from zidovudine?. HIV Med 10 (7): 397–406.

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Gibb DM, Kizito H, Russell EC, Chidziva E, Zalwango E, Nalumenya R, Spyer M, Tumukunde D, Nathoo K, Munderi P, Kyomugisha H, Hakim J, Grosskurth H, Gilks CF, Walker AS, Musoke P (2012) Pregnancy and infant outcomes among HIV-infected women taking long-term ART with and without tenofovir in the DART trial. PLoS Med  9(5): e1001217.

Gibson F, Chisholm J, Blandford E, Donachie P, Hartley J, Lane S, Selwood K, Skinner R, Phillips R: Developing a national 'low risk' febrile neutropenia guideline in children and young people's cancer care. Supportive Care in Cancer 2013, In Press.

Giles I, Pericleous C, Liu X, Ehsanullah J, Clarke L, Brogan P, Newton-West M, Swerlick R, Lambrianides A, Chen P, Latchman D, Isenberg D, Pierangeli S, Rahman A (2009) Thrombin binding predicts the effects of sequence changes in a human monoclonal antiphospholipid antibody on its in vivo biologic actions. J Immunol 182 (8): 4836–43.

Gilks CF, Walker AS, Dunn DT, Gibb DM, Kikaire B, Reid A, Musana H, Mambule I, Kasirye R, Robertson V, Ssali F, Spyer M, Pillay D, Yirrell D, Kaleebu P (2012) Lopinavir/ritonavir monotherapy after 24 weeks of second-line antiretroviral therapy in Africa: a randomized controlled trial (SARA). Antivir Ther 17:1363-1373.

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Girard F, Frankel G, Phillips AD, Cooley W, Weyer U, Dugdale AH, Woodward MJ, La Ragione RM (2008) Interaction of enterohemorrhagic Escherichia coli O157:H7 with mouse intestinal mucosa. FEMS Microbiol Lett 283 (2): 196–202.

Gjelstrup LC, Boesen T, Kragstrup TW, Jørgensen A, Klein NJ, Thiel S, Deleuran BW, Vorup-Jensen T (2010) Shedding of large functionally active CD11/CD18 Integrin complexes from leukocyte membranes during synovial inflammation distinguishes three types of arthritis through differential epitope exposure. J Immunol 185 (7): 4154-68.

Goetghebuer T, Haelterman E, Le Chenadec J, Dollfus C, Gibb D, Judd A, Green H, Galli L, Ramos JT, Giaquinto C, Warszawski J, Levy J, European Infant Collaboration group (2009) Effect of early antiretroviral therapy on the risk of AIDS/death in HIV-infected infants. AIDS 23 (5): 597–604.

Grant KA, Nwarfor I, Mpamugo O, Mithani V, Lister P, Dixon G, Nixon G, Planche T, Courtney M, Morgan J, McLauchlin J (2009) Report of two unlinked cases of infant botulism in the UK in October 2007. J Med Microbiol 58 (Pt 12): 1601–6.

Green H, Gibb DM, Walker AS, Pillay D, Butler K, Candeias F, Castelli-Gattinara G, Compagnucci A, Della Negra M, de Rossi A, Feiterna-Sperling C, Giaquinto C, Harper L, Levy J, Saidi Y, Wintergerst U, Paediatric European Network for the Treatment of AIDS (PENTA) (2007) Lamivudine/abacavir maintains virological superiority over zidovudine/lamivudine and zidovudine/abacavir beyond 5 years in children. AIDS 21 (8): 947–55.

Guerry MJ, Brogan P, Bruce IN, D'Cruz DP, Harper L, Luqmani R, Pusey CD, Salama AD, Scott DG, Savage CO, Watts RA, Jayne DR (2011) Recommendations for the use of rituximab in anti-neutrophil cytoplasm antibody-associated vasculitis. Rheumatology (Oxford) [Epub ahead of print].

Gupta RK, Ford D, Mulenga V, Walker AS, Kabamba D, Kalumbi M, Grant PR, Ferrier A, Pillay D, Gibb DM, Chintu C (2010) Drug resistance in human immunodeficiency virus type-1 infected Zambian children using adult fixed dose combination stavudine, lamivudine, and nevirapine. Pediatr Infect Dis J 29 (8): e57-62.

Gupta RK, Gibb DM, Pillay D (2009) Management of paediatric HIV-1 resistance. Curr Opin Infect Dis 22 (3): 256–63.

Haberer JE, Cook A, Walker AS, Ngambi M, Ferrier A, Mulenga V, Kityo C, Thomason M, Kabamba D, Chintu C, Gibb DM, Bangsberg DR (2011) Excellent adherence to antiretrovirals in HIV+ Zambian children is compromised by disrupted routine, HIV nondisclosure, and paradoxical income effects. PLoS One 6(4): e18505.

Hall S, Brogan P, Haworth SG, Klein N (2009) Contribution of inflammation to the pathology of idiopathic pulmonary arterial hypertension in children. Thorax 64 (9): 778–83.

Hall SM, Davie N, Klein N, Haworth SG (2011) Endothelin receptor expression in IPAH: effect of bosentan and epoprostenol treatment. Eur Respir J 38: 851-60

Hardelid P, Williams D, Dezateux C, Cubitt WD, Peckham CS, Tookey PA, Cortina-Borja M (2008) Agreement of rubella IgG antibody measured in serum and dried blood spots using two commercial enzyme-linked immunosorbent assays. J Med Virol 80 (2): 360–4.

Hardelid P, Williams D, Dezateux C, Tookey PA, Peckham CS, Cubitt WD, Cortina-Borja M (2008) Analysis of rubella antibody distribution from newborn dried blood spots using finite mixture models. Epidemiol Infect 1: 1–9.

Harris KA, Kenna DT, Blauwendraat C, Hartley JC, Turton JF, Aurora P, Dixon GL (2012) Molecular fingerprinting of Mycobacterium abscessus strains in a cohort of pediatric cystic fibrosis patients. J Clin Microbiol 50(5): 1758-61.

Harris K A, Turner P, Green E A, Hartley J C (2008) Duplex real-time PCR assay for detection of Streptococcus pneumoniae in clinical samples and determination of penicillin susceptibility. J Clin MicrobiolJournal of clinical microbiology 46: 2751–8.

Harris HE, Mieli-Vergani G, Kelly D, Davison S, Gibb DM, Ramsay ME, HCV National Register Steering Group (2007) A national sample of individuals who acquired hepatitis C virus infections in childhood or adolescence: risk factors for advanced disease. J Pediatr Gastroenterol Nutr 45 (3): 335–41.

Harrison L, Ananworanich J, Hamadache D, Compagnucci A, Penazzato M, Bunupuradah T, Mazza A, Ramos JT, Flynn J, Rampon O, Mellado PMJ, Floret D, Marczynska M, Puga A, Forcat S, Riault Y, Lallemant M, Castro H, Gibb DM, Giaquinto C (2012) Adherence to Antiretroviral Therapy and Acceptability of Planned Treatment Interruptions in HIV-Infected Children. AIDS Behav E-Pub

Haustein T, Ridout DA, Hartley JC, Thaker U, Shingadia D, Klein NJ, Novelli V, Dixon GL (2009) The likelihood of an indeterminate test result from a whole-blood interferon-gamma release assay for the diagnosis of Mycobacterium tuberculosis infection in children correlates with age and immune status. Pediatr Infect Dis J 28 (8): 669–73.

Hawkins C, Harper D, Burch D, Anggård E, Soothill J (2010) Topical treatment of Pseudomonas aeruginosa otitis of dogs with a bacteriophage mixture: A before/after clinical trial. Vet Microbiol 146: 309–313

Hemrajani C, Marches O, Wiles S, Girard F, Dennis A, Dziva F, Best A, Phillips AD, Berger CN, Mousnier A, Crepin VF, Kruidenier L, Woodward MJ, Stevens MP, La Ragione RM, MacDonald TT, Frankel G (2008) Role of NleH, a type III secreted effector from attaching and effacing pathogens, in colonization of the bovine, ovine, and murine gut. Infect Immun 76 (11): 4804–13.

Henin E, Bergstrand M, Standing JF, Karlsson MO (2012) A mechanism-based approach for absorption modeling: the Gastro-Intestinal Transit Time (GITT) model. Aaps J 14(2): 155-63.

HIV Paediatric Prognostic Markers Collaborative Study, Boyd K, Dunn DT, Castro H, Gibb DM, Duong T, Aboulker JP, Bulterys M, Cortina-Borja M, Gabiano C, Galli L, Giaquinto C, Harris DR, HugheS M, McKinney R, Mofenson L, Moye J, Newell ML, Pahwa S, Palumbo P, Rudin C, Sharland M, Shearer W, Thompson B, Tookey P (2010) Discordance between CD4 cell count and CD4 cell percentage: implications for when to start antiretroviral therapy in HIV-1 infected children. AIDS 24(8): 1213-7.

Hong Y, Eleftheriou D, Hussain AA, Price-Kuehne FE, Savage CO, Jayne D, Little MA, Salama AD, Klein NJ, Brogan PA (2012) Anti-neutrophil cytoplasmic antibodies stimulate release of neutrophil microparticles. J Am Soc Nephrol 23(1): 49-62.

Hoskote AU, Ramaiah RN, Cale CM, Hartley JC, Brown KL: Role of immunoglobulin supplementation for secondary immunodeficiency associated with chylothorax after pediatric cardiothoracic surgery*. Pediatr Crit Care Med 2012, 13:535-541.

Hutchinson E, Parkhurst J, Phiri S, Gibb DM, Chishinga N, Droti B, Hoskins S (2011) National policy development for cotrimoxazole prophylaxis in Malawi, Uganda and Zambia: the relationship between Context, Evidence and Links. Health Res Policy Syst 9 Suppl 1: S6.

Jacobsen MC, Thiébaut R, Fisher C, Sefe D, Clapson M, Klein N, Baxendale HE (2008) Pediatric Human Immunodeficiency Virus Infection and Circulating IgD(+) Memory B Cells. J Infect Dis 198 (4): 481–485.

Jafari NV, Allan E, Bajaj-Elliott M (2010) Human intestinal epithelial response(s) to Clostridium difficile. Methods Mol Biol 646: 135-46.

Januário G, Ramroop S, Shingadia DV, Novelli V (2010) Postinfectious purpura fulminans secondary to varicella-induced protein S deficiency. Pediatr Infect Dis J 29 (10): 981-3.

Jaspan HB, Myer L, Madhi SA, Violari A, Gibb DM, Stevens WS, Dobbels E, Cotton MF (2011) Utility of clinical parameters to identify HIV infection in infants below ten weeks of age in South Africa: a prospective cohort study. BMC Pediatr 11: 104.

Johansson AM, Hill N, Perisoglou M, Whelan J, Karlsson MO, Standing JF (2011) A Population Pharmacokinetic/Pharmacodynamic Model of Methotrexate and Mucositis Scores in Osteosarcoma. Therapeutic Drug Monitoring  33(6): 711-8.

Jones HE, Klein N, Dixon GL (2012) Human dendritic cell culture and bacterial infection. Methods Mol Biol 799: 217-35.

Jones H E, Strid J, Osman M, Uronen-Hansson H, Dixon G, Klein N, Wong S Y, Callard R E (2008) The role of beta2 integrins and lipopolysaccharide-binding protein in the phagocytosis of dead Neisseria meningitidis. Cell Microbiol 10: 1634–45.

Jones HE, Harris KA, Azizia M, Bank L, Carpenter B, Hartley JC, Klein N, Peebles D (2009) Differing prevalence and diversity of bacterial species in fetal membranes from very preterm and term labor. PLoS One 4 (12): e8205.

Jones HE, Uronen-Hansson H, Callard RE, Klein N, Dixon GL (2007) The differential response of human dendritic cells to live and killed Neisseria meningitidis. Cell Microbiol 9 (12): 2856–69.

Jones RB, Ferraro AJ, Chaudhry AN, Brogan P, Salama AD, Smith KG, Savage CO, Jayne DR (2009) A multicenter survey of rituximab therapy for refractory antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheum 60 (7): 2156–68.

Jones SM, Weinstein JM, Cumberland P, Klein N, Nischal KK (2007) Visual outcome and corneal changes in children with chronic blepharokeratoconjunctivitis. Ophthalmology 114 (12): 2271–80.

Judd A, Boyd KL, Stöhr W, Dunn D, Butler K, Lyall H, Sharland M, Shingadia D, Riordan A, Gibb DM (2010) Effect of tenofovir disoproxil fumarate on risk of renal abnormality in HIV-1-infected children on antiretroviral therapy: a nested case-control study. AIDS 24 (4): 525–34.

Judd A, Doerholt K, Tookey PA, Sharland M, Riordan A, Menson E, Novelli V, Lyall EG, Masters J, Tudor-Williams G, Duong T, Gibb DM, Collaborative HIV Paediatric Study (CHIPS), National Study of HIV in Pregnancy and Childhood (NSHPC) (2007) Morbidity, mortality, and response to treatment by children in the United Kingdom and Ireland with perinatally acquired HIV infection during 1996-2006: planning for teenage and adult care. Clin Infect Dis 45 (7): 918–24.

Kandasamy J, Dwan K, Hartley JC, Jenkinson MD, Hayhurst C, Gatscher S, Thompson D, Crimmins D, Mallucci C (2011) Antibiotic-impregnated ventriculoperitoneal shunts--a multi-centre British paediatric neurosurgery group (BPNG) study using historical controls. Childs Nerv Syst 27(4): 575-81.

Kasirye P, Kendall L, Adkison KK, Tumusiime C, Ssenyonga M, Bakeera-Kitaka S, Nahirya-Ntege P, Mhute T, Kekitiinwa A, Snowden W, Burger DM, Gibb DM, Walker AS (2012) Pharmacokinetics of Antiretroviral Drug Varies With Formulation in the Target Population of Children With HIV-1. Clin Pharmacol Ther 91(2): 272-80

Kekitiinwa A, Lee KJ, Walker AS, Maganda A, Doerholt K, Kitaka SB, Asiimwe A, Judd A, Musoke P, Gibb DM, Collaborative HIV Paediatric Study (CHIPS) Steering Committe, Mulago Cohort Team (2008) Differences in factors associated with initial growth, CD4, and viral load responses to ART in HIV-infected children in Kampala, Uganda, and the United Kingdom/Ireland. J Acquir Immune Defic Syndr 49 (4): 384–92.

Kenny J, Musiime V, Judd A, Gibb D (2012) Recent advances in pharmacovigilance of antiretroviral therapy in HIV-infected and exposed children. Curr Opin HIV AIDS  7(4): 305-16.

Kiang KM, Bryant PA, Shingadia D, Ladhani S, Steer AC, Burgner D: The treatment of imported malaria in children: an update. Arch Dis Child Educ Pract Ed 2012.

Kikaire B, Khoo S, Walker AS, Ssali F, Munderi P, Namale L, Reid A, Gibb DM, Mugyenyi P, Grosskurth H, DART Trial Team (2007) Nevirapine clearance from plasma in African adults stopping therapy: a pharmacokinetic substudy. AIDS 21 (6): 733–7.

Kityo C, Walker AS, Dickinson L, Lutwama F, Kayiwa J, Ssali F, Nalumenya R, Tumukunde D, Munderi P, Reid A, Gilks CF, Gibb DM, Khoo S; DART Trial Team (2010) Pharmacokinetics of lopinavir-ritonavir with and without nonnucleoside reverse transcriptase inhibitors in Ugandan HIV-infected adults. Antimicrob Agents Chemother 54(7): 2965-73.

Koliou MG, Soteriades ES, Ephros M, Mazeris A, Antoniou M, Elia A, Novelli V (2008) Hemophagocytic lymphohistiocytosis associated with Epstein Barr virus and Leishmania donovani coinfection in a child from Cyprus. J Pediatr Hematol Oncol 30 (9): 704–7.

Krishnaiah A, Soothill J, Wade A, Mok QQ, Ramnarayan P (2011) Central venous catheter associated blood stream infections in a paediatric intensive care unit: effect of the location of catheter insertion. Pediatric Critical Care Medicine 13:e176-180.

L'homme RF, Dijkema T, Warris A, van der Ven AJ, Gibb DM, Burger DM (2007) Pharmacokinetics of two generic fixed-dose combinations for HIV-infected children (Pedimune Baby & Pedimune Junior) are similar to the branded products in healthy adults. J Antimicrob Chemother 59 (1): 92–6.

L'homme RF, Kabamba D, Ewings FM, Mulenga V, Kankasa C, Thomason MJ, Walker AS, Chintu C, Burger DM, Gibb DM (2008) Nevirapine, stavudine and lamivudine pharmacokinetics in African children on paediatric fixed-dose combination tablets. AIDS 22 (5): 557–65.

Ladhani S, Aibara RJ, Riordan FA, Shingadia D (2007) Imported malaria in children: a review of clinical studies. Lancet Infect Dis 7 (5): 349–57.

Ladhani S, Garbash M, Whitty CJ, Chiodini PL, Aibara RJ, Riordan FA, Shingadia D (2010) Prospective, national clinical and epidemiologic study on imported childhood malaria in the United Kingdom and the Republic of Ireland. Pediatr Infect Dis J 29(5): 434-8.

Lalloo DG, Shingadia D, Pasvol G, Chiodini PL, Whitty CJ, Beeching NJ, Hill DR, Warrell DA, Bannister BA, HPA Advisory Committee on Malaria Prevention in UK Travellers (2007) UK malaria treatment guidelines. J Infect 54 (2): 111–21.

Lanemo Myhrinder A, Hellqvist E, Sidorova E, Söderberg A, Baxendale H, Dahle C, Willander K, Tobin G, Bäckman E, Söderberg O, Rosenquist R, Hörkkö S, Rosén A (2008) A new perspective: molecular motifs on oxidized LDL, apoptotic cells, and bacteria are targets for chronic lymphocytic leukemia antibodies. Blood 111 (7): 3838–48.

Laughton B, Cornell M, Grove D, Kidd M, Springer PE, Dobbels E, Rensburg AJ, Violari A, Babiker AG, Madhi SA, Jean-Philippe P, Gibb DM, Cotton MF (2012) Early antiretroviral therapy improves neurodevelopmental outcomes in infants. Aids  26:1685-1690.

Laurie KL, Blundell MP, Baxendale HE, Howe SJ, Sinclair J, Qasim W, Brunsberg U, Thrasher AJ, Holmdahl R, Gustafsson K (2007) Cell-specific and efficient expression in mouse and human B cells by a novel hybrid immunoglobulin promoter in a lentiviral vector. Gene Ther 14 (23): 1623–31.

Lee KJ, Shingadia D, Pillay D, Walker AS, Riordan A, Menson E, Duong T, Tudor-Williams G, Gibb DM, Collaborative HIV Paediatric Study Steering Committee (2007) Transient viral load increases in HIV-infected children in the U.K. and Ireland: what do they mean?. Antivir Ther 12 (6): 949–56.

Lewis J, Walker AS, Castro H, De RA, Gibb DM, Giaquinto C, Klein N, Callard R (2012) Reply to zhang, poznansky, and crumpacker. J Infect Dis 206(4): 618.

Lewis J, Walker AS, Klein N, Callard R (2012) CD31+ Cell Percentage Correlation With Speed of CD4+ T-Cell Count Recovery in HIV-Infected Adults Is Reversed in Children: Higher Thymic Output May Be Responsible. Clin Infect Dis  55(2): 304-7.

Lewis J, Walker AS, Castro H, De RA, Gibb DM, Giaquinto C, Klein N, Callard R (2012) Age and CD4 Count at Initiation of Antiretroviral Therapy in HIV-Infected Children: Effects on Long-term T-Cell Reconstitution. J Infect Dis 205(4): 548-56.

Lloyd J, Allen M, Azizia M, Klein N, Peebles D (2007) Monocyte major histocompatibility complex class II expression in term and preterm labor. Obstet Gynecol 110 (6): 1335–42.

Lopez PJ, Ron O, Parthasarathy P, Soothill J, Spitz L (2009) Bacterial counts from hospital doctors' ties are higher than those from shirts. Am J Infect Control 37 (1): 79–80.

Lozanoska-Ochser B, Klein NJ, Huang GC, Alvarez RA, Peakman M (2008) Expression of CD86 on human islet endothelial cells facilitates T cell adhesion and migration. J Immunol 181 (9): 6109–16.

Lutsar I, Trafojer UMT, Heath PT, Metsvaht T, Standing J, Esposito S, de Cabre VM, Oeser C, Aboulker J-P (2011) Meropenem vs standard of care for treatment of late onset sepsis in children of less than 90 days of age: study protocol for a randomised controlled trial. Trials  12: 215.

Maiya S, Sullivan I, Allgrove J, Yates R, Malone M, Brain C, Archer N, Mok Q, Daubeney P, Tulloh R, Burch M (2008) Hypocalcaemia and vitamin D deficiency: an important, but preventable, cause of life-threatening infant heart failure. Heart 94 (5): 581–4.

Maitland K, Kiguli S, Opoka RO, Engoru C, Olupot-Olupot P, Akech SO, Nyeko R, Mtove G, Reyburn H, Lang T, Brent B, Evans JA, Tibenderana JK, Crawley J, Russell EC, Levin M, Babiker AG, Gibb DM (2011) Mortality after fluid bolus in African children with severe infection. N Engl J Med 364(26): 2483-95.

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Marks SD, Shah V, Pilkington C, Tullus K (2010) Urinary monocyte chemoattractant protein-1 correlates with disease activity in lupus nephritis. Pediatr Nephrol 25 (11): 2283-8.

Masi S, Nightingale CM, Day IN, Guthrie P, Rumley A, Lowe GD, von ZT, D'Aiuto F, Taddei S, Klein N, Salpea K, Cook DG, Humphries SE, Whincup PH, Deanfield JE (2012) Inflammation and not cardiovascular risk factors is associated with short leukocyte telomere length in 13- to 16-year-old adolescents. Arterioscler Thromb Vasc Biol  32(8): 2029-34.

Mbisa JL, Gupta RK, Kabamba D, Mulenga V, Kalumbi M, Chintu C, Parry CM, Gibb DM, Walker SA, Cane PA, Pillay D (2011) The evolution of HIV-1 reverse transcriptase in route to acquisition of Q151M multi-drug resistance is complex and involves mutations in multiple domains. Retrovirology 8: 31.

McCormick AL, Goodall RL, Joyce A, Ndembi N, Chirara M, Katundu P, Walker S, Yirrell D, Gilks CF, Pillay D; DART Virology Group and Trial Team (2010) Lack of minority K65R-resistant viral populations detected after repeated treatment interruptions of tenofovir/zidovudine and lamivudine in a resource-limited setting. J Acquir Immune Defic Syndr 54(2): 215-6.

Medina LA, Kigozi J, Amurwon J, Muchabaiwa L, Nyanzi WB, Mujica MRE, Walker AS, Kasirye R, Ssali F, Reid A, Grosskurth H, Babiker AG, Kityo C, Katabira E, Munderi P, Mugyenyi P, Hakim J, Darbyshire J, Gibb DM, Gilks CF (2012) Cost effectiveness analysis of clinically driven versus routine laboratory monitoring of antiretroviral therapy in Uganda and Zimbabwe. PLoS One 7(4): e33672.

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Melly L, Sebire NJ, Malone M, Nicholson AG (2008) Capillary apposition and density in the diagnosis of alveolar capillary dysplasia. Histopathology 53 (4): 450–7.

Melo Gomes S, Glover M, Malone M, Brogan P: Vasculitis following HPV immunization. Rheumatology (Oxford) 2012.

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Mulenga V, Cook A, Walker AS, Kabamba D, Chijoka C, Ferrier A, Kalengo C, Kityo C, Kankasa C, Burger D, Thomason M, Chintu C, Gibb DM (2010) Strategies for nevirapine initiation in HIV-infected children taking pediatric fixed-dose combination "baby pills" in Zambia: a randomized controlled trial. Clin Infect Dis 51 (9): 1081-9.

Mulenga V, Ford D, Walker AS, Mwenya D, Mwansa J, Sinyinza F, Lishimpi K, Nunn A, Gillespie S, Zumla A, Chintu C, Gibb DM, CHAP Trial Team (2007) Effect of cotrimoxazole on causes of death, hospital admissions and antibiotic use in HIV-infected children. AIDS 21 (1): 77–84.

Munderi P, Walker AS, Kityo C, Babiker AG, Ssali F, Reid A, Darbyshire JH, Grosskurth H, Mugyenyi P, Gibb DM, Gilks CF; DART/NORA trial teams (2010) Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48-week randomized comparison with abacavir/zidovudine/lamivudine in HIV-infected Ugandan adults with low CD4 cell counts. HIV Med 11(5): 334-44.

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Muorah MR, Brogan PA, Sebire NJ, Trompeter RS, Marks SD (2009) Dense B cell infiltrates in paediatric renal transplant biopsies are predictive of allograft loss. Pediatr Transplant 13 (2): 217–22.

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Musiime V, Kendall L, Bakeera-Kitaka S, Snowden WB, Odongo F, Thomason M, Musoke P, Adkison K, Burger D, Mugyenyi P, Kekitiinwa A, Gibb DM, Walker AS (2010)
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Muyingo SK, Walker AS, Reid A, Munderi P, Gibb DM, Ssali F, Levin J, Katabira E, Gilks C, Todd J, the DART Trial Team (2008) Patterns of Individual and Population-Level Adherence to Antiretroviral Therapy and Risk Factors for Poor Adherence in the First Year of the DART Trial in Uganda and Zimbabwe. J Acquir Immune Defic Syndr 48 (4): 468–475.

Mwenya DM, Charalambous BM, Phillips PP, Mwansa JC, Batt SL, Nunn AJ, Walker S, Gibb DM, Gillespie SH (2010) Impact of cotrimoxazole on carriage and antibiotic resistance of Streptococcus pneumoniae and Haemophilus influenzae in HIV-infected children in Zambia. Antimicrob Agents Chemother 54 (9): 3756-62.

Nahirya-Ntege P, Cook A, Vhembo T, Opilo W, Namuddu R, Katuramu R, Tezikyabbiri J, Naidoo-James B, Gibb D (2012) Young HIV-infected children and their adult caregivers prefer tablets to syrup antiretroviral medications in Africa. PLoS One 7(5): e36186.

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Ndembi N, Goodall RL, Dunn DT, McCormick A, Burke A, Lyagoba F, Munderi P, Katundu P, Kityo C, Robertson V, Yirrell DL, Walker AS, Gibb DM, Gilks CF, Kaleebu P, Pillay D, Development of Antiretroviral Treatment in Africa Virology Group and Trial Team (2010) Viral rebound and emergence of drug resistance in the absence of viral load testing: a randomized comparison between zidovudine-lamivudine plus Nevirapine and zidovudine-lamivudine plus Abacavir. J Infect Dis 201 (1): 106–13.

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Prendergast A, Bwakura-Dangarembizi M, Cook A, Bakeera-Kitaka S, Natukunda E, Nahirya P, Nathoo K, Karungi C, Lutaakome J, Kekitiinwa A, Gibb DM (2011) Hospitalisation for severe malnutrition amongst HIV-infected children starting antiretroviral therapy. Aids 25(7): 951-6.

Prendergast A, Walker AS, Mulenga V, Chintu C, Gibb DM (2011) Improved Growth and Anemia in HIV-Infected African Children Taking Cotrimoxazole Prophylaxis. Clin Infect Dis 52 (7): 953-6.

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Pryce JW, Weber MA, Heales S, Malone M, Sebire NJ (2011) Tandem mass spectrometry findings at autopsy for detection of metabolic disease in infant deaths: postmortem changes and confounding factors. J Clin Pathol 64(11): 1005-9.

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Ramroop S, Williams B, Vora S, Moshal K: Infant botulism and botulism immune globulin in the UK: a case series of four infants. Arch Dis Child 2012, 97:459-460.

Reid A, Stöhr W, Walker AS, Williams IG, Kityo C, Hughes P, Kambugu A, Gilks CF, Mugyenyi P, Munderi P, Hakim J, Gibb DM, Development of Antiretroviral Therapy Trial (2008) Severe Renal Dysfunction and Risk Factors Associated with Renal Impairment in HIV-Infected Adults in Africa Initiating Antiretroviral Therapy. Clin Infect Dis 46 (8): 1271–1281.

Rice GI, Kasher PR, Forte GM, Mannion NM, Greenwood SM, Szynkiewicz M, Dickerson JE, Bhaskar SS, Zampini M, Briggs TA, et al.: Mutations in ADAR1 cause Aicardi-Goutieres syndrome associated with a type I interferon signature. Nat Genet 2012, 44:1243-1248.

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Riordan A, Judd A, Boyd K, Cliff D, Doerholt K, Lyall H, Menson E, Butler K, Gibb D, Collaborative HIV Paediatric Study (2009) Tenofovir use in human immunodeficiency virus-1-infected children in the United kingdom and Ireland. Pediatr Infect Dis J 28 (3): 204–9.

Roberts SE, Pryce JW, Weber MA, Malone M, Ashworth MT, Sebire NJ (2012) Clinicopathological features of fatal cardiomyopathy in childhood: An autopsy series. J Paediatr Child Health 48:675-680.

Robinson PD, Harris KA, Jerkic SP, Aurora P, Hartley JC, Spencer H: Post lung transplant outcomes in children colonised with differing Mycobacterium abscessus complex species. European Respiratory Journal 2013, In Press.

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Ryan M, Griffin S, Chitah B, Walker AS, Mulenga V, Kalolo D, Hawkins N, Merry C, Barry MG, Chintu C, Sculpher MJ, Gibb DM (2008) The cost-effectiveness of cotrimoxazole prophylaxis in HIV-infected children in Zambia. AIDS 22 (6): 749–57.

Saldaña Z, Erdem AL, Schüller S, Okeke IN, Lucas M, Sivananthan A, Phillips AD, Kaper JB, Puente JL, Girón JA (2009) The Escherichia coli common pilus and the bundle-forming pilus act in concert during the formation of localized adherence by enteropathogenic E. coli. J Bacteriol 191 (11): 3451–61.

Saldaña Z, Xicohtencatl-Cortes J, Avelino F, Phillips AD, Kaper JB, Puente JL, Girón JA (2009) Synergistic role of curli and cellulose in cell adherence and biofilm formation of attaching and effacing Escherichia coli and identification of Fis as a negative regulator of curli. Environ Microbiol 11 (4): 992–1006.

Schüller S, Chong Y, Lewin J, Kenny B, Frankel G, Phillips AD (2007) Tir phosphorylation and Nck/N-WASP recruitment by enteropathogenic and enterohaemorrhagic Escherichia coli during ex vivo colonization of human intestinal mucosa is different to cell culture models. Cell Microbiol 9 (5): 1352–64.

Schüller S, Heuschkel R, Torrente F, Kaper JB, Phillips AD (2007) Shiga toxin binding in normal and inflamed human intestinal mucosa. Microbes Infect 9 (1): 35–9.

Schüller S, Lucas M, Kaper JB, Girón JA, Phillips AD (2009) The ex vivo response of human intestinal mucosa to enteropathogenic Escherichia coli infection. Cell Microbiol 11 (3): 521–30.

Schüller S, Phillips AD  (2010) Microaerobic conditions enhance type III secretion and adherence of enterohaemorrhagic Escherichia coli to polarized human intestinal epithelial cells. Environ Microbiol 12 (9): 2426-35.

Sebire NJ, Weber MA, Thayyil S, Mushtaq I, Taylor A, Chitty LS (2011) Minimally invasive perinatal autopsies using magnetic resonance imaging and endoscopic postmortem examination ("keyhole autopsy"): feasibility and initial experience. J Matern Fetal Neonatal Med

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Shah N, Cambrook H, Koglmeier J, Mason C, Ancliff P, Lindley K, Smith VV, Bajaj-Elliott M, Sebire NJ (2010) Enteropathic histopathological features may be associated with Shwachman-Diamond syndrome. J Clin Pathol 63(7): 592-4.

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Simmonds J, Fenton M, Dewar C, Ellins E, Storry C, Cubitt D, Deanfield J, Klein N, Halcox J, Burch M (2008) Endothelial dysfunction and cytomegalovirus replication in pediatric heart transplantation. Circulation 117 (20): 2657–61.

Smith CM, Lo Passo C, Scuderi A, Kolberg J, Baxendale H, Goldblatt D, Oggioni MR, Felici F, Andrew PW (2009) Peptide mimics of two pneumococcal capsular polysaccharide serotypes (6B and 9V) protect mice from a lethal challenge with Streptococcus pneumoniae. Eur J Immunol 39 (6): 1527–35.

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Standing AS, Eleftheriou D, Lachmann HJ, Brogan PA (2011) Familial Mediterranean fever caused by homozygous E148Q mutation complicated by Budd-Chiari syndrome and polyarteritis nodosa. Rheumatology (Oxford) 50(3): 624-6.

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