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Recent publications

Bains I, Antia R, Callard R, Yates AJ (2009) Quantifying the development of the peripheral naive CD4+ T-cell pool in humans. Blood 113 (22): 5480–7.

Bains I, Thiébaut R, Yates AJ, Callard R (2009) Quantifying thymic export: combining models of naive T cell proliferation and TCR excision circle dynamics gives an explicit measure of thymic output. J Immunol 183 (7): 4329–36.

Barenco M, Brewer D, Papouli E, Tomescu D, Callard R, Stark J, Hubank M (2009) Dissection of a complex transcriptional response using genome-wide transcriptional modelling. Mol Syst Biol 5: 327.
Baxendale HE, Keating SM, Johnson M, Southern J, Miller E, Goldblatt D (2010) The early kinetics of circulating pneumococcal-specific memory B cells following pneumococcal conjugate and plain polysaccharide vaccines in the elderly. Vaccine 28 (30): 4763-70.
Baxendale HE, Johnson M, Keating SM, Ashton L, Burbidge P, Woodgate S, Southern J, Miller E, Goldblatt D (2010) Circulating pneumococcal specific plasma and memory B cells in the elderly two years after pneumococcal conjugate versus polysaccharide vaccination. Vaccine 28(42): 6915-22.
Baxendale HE, Johnson M, Stephens RC, Yuste J, Klein N, Brown JS, Goldblatt D (2008) Natural human antibodies to pneumococcus have distinctive molecular characteristics and protect against pneumococcal disease. Clin Exp Immunol 151 (1): 51–60.

Bennett K, Heywood W, Di WL, Harper J, Clayman GL, Jayakumar A, Callard R, Mills K (2012) The identification of a new role for LEKTI in the skin: The use of protein 'bait' arrays to detect defective trafficking of dermcidin in the skin of patients with Netherton syndrome. J Proteomics 75(13): 3925-37.
Bennett K, Callard R, Heywood W, Harper J, Jayakumar A, L Clayman G, Di WL, Mills K (2010) New role for LEKTI in skin barrier formation: label-free quantitative proteomic identification of caspase 14 as a novel target for the protease inhibitor LEKTI. J Proteome Res 9(8): 4289-94.
Blaydon DC, Biancheri P, Di WL, Plagnol V, Cabral RM, Brooke MA, van HDA, Ruschendorf F, Toynbee M, Walne A, O'Toole EA, Martin JE, Lindley K, Vulliamy T, Abrams DJ, MacDonald TT, Harper JI, Kelsell DP (2011) Inflammatory skin and bowel disease linked to ADAM17 deletion. N Engl J Med 365(16): 1502-8.
Brewer D, Barenco M, Callard R, Hubank M, Stark J (2008) Fitting ordinary differential equations to short time course data. Philos Transact A Math Phys Eng Sci 366 (1865): 519–44.

Byrne C, Avilion AA, O'Shaughnessy RF, Welti JC, Hardman MJ (2010) Whole-mount assays for gene induction and barrier formation in the developing epidermis. Methods Mol Biol 585: 271-86.
Cale CM, Morton L, Goldblatt D (2007) Cutaneous and other lupus-like symptoms in carriers of X-linked chronic granulomatous disease: incidence and autoimmune serology. Clin Exp Immunol 148 (1): 79–84.

Callard R (2008) Response to letter by Mohammad Reza Namazi. Trends Immunol 29 (1): 3.

Callard R, Hodgkin P (2007) Modeling T- and B-cell growth and differentiation. Immunol Rev 216: 119–29.

Callard RE (2007) Decision-making by the immune response. Immunol Cell Biol 85 (4): 300–5.

Callard RE, Harper JI (2007) The skin barrier, atopic dermatitis and allergy: a role for Langerhans cells?. Trends Immunol 28 (7): 294–8.

Chan SM, Dillon MJ, Duffy PG, Atherton DJ (2007) Nephro-urological complications of epidermolysis bullosa in paediatric patients. Br J Dermatol 156 (1): 143–7.

Cole TS, Jones LK, McGrogan P, Pearce MS, Flood TJ, Cant AJ, Goldblatt D, Thrasher AJ, Gennery AR, McKendrick F, Titman P (2012) Emotional and behavioural difficulties in chronic granulomatous disease. Arch Dis Child  97(1): 87.
Cole T, McKendrick F, Titman P, Cant AJ, Pearce MS, Cale CM, Goldblatt D, Gennery AR: Health Related Quality of Life and Emotional Health in Children with Chronic Granulomatous Disease: A Comparison of Those Managed Conservatively with Those That Have Undergone Haematopoietic Stem Cell Transplant. J Clin Immunol 2012.
Crawley J, Sismanidis C, Goodman T, Milligan P: Effect of intermittent preventive treatment for malaria during infancy on serological responses to measles and other vaccines used in the Expanded Programme on Immunization: results from five randomised controlled trials. Lancet 2012, 380:1001-1010.
Crompton T, Outram SV, Hager-Theodorides AL (2007) Sonic hedgehog signalling in T-cell development and activation. Nat Rev Immunol 7 (9): 726–35.

D'Acquisto F, Crompton T (2011) CD3(+)CD4(-)CD8(-) (double negative) T cells: Saviours or villains of the immune response? Biochemical Pharmacology 82(4):333-40.
Denoël PA, Goldblatt D, de Vleeschauwer I, Jacquet JM, Pichichero ME, Poolman JT (2007) Quality of the Haemophilus influenzae type b (Hib) antibody response induced by diphtheria-tetanus-acellular pertussis/Hib combination vaccines. Clin Vaccine Immunol 14 (10): 1362–9.

Denoël PA, Goldblatt D, de Vleeschauwer I, Jacquet JM, Pichichero ME, Poolman JT (2007) Quality of the Haemophilus influenzae type b (Hib) antibody response induced by diphtheria-tetanus-acellular pertussis/Hib combination vaccines. Clin Vaccine Immunol 14 (10): 1362–9.

Di WL, Semenova E, Larcher F, Del RM, Harper JI, Thrasher A, Qasim W (2012) Human involucrin promoter mediates repression resistant and compartment specific LEKTI expression. Hum Gene Ther 23(1): 83-90.
Di WL, Larcher F, Semenova E, Talbot GE, Harper JI, Del Rio M, Thrasher AJ, Qasim W (2011) Ex-vivo Gene Therapy Restores LEKTI Activity and Corrects the Architecture of Netherton Syndrome-derived Skin Grafts. Mol Ther 19 (2): 408-16.
Di WL, Hennekam RC, Callard RE, Harper JI (2009) A heterozygous null mutation combined with the G1258A polymorphism of SPINK5 causes impaired LEKTI function and abnormal expression of skin barrier proteins. Br J Dermatol 161 (2): 404–12.

Ding Y, Brackenbury WJ, Onganer PU, Montano X, Porter LM, Bates LF, Djamgoz MB (2008) Epidermal growth factor upregulates motility of Mat-LyLu rat prostate cancer cells partially via voltage-gated Na+ channel activity. J Cell Physiol 215 (1): 77–81.

Drakopoulou E, Outram SV, Rowbotham NJ, Ross SE, Furmanski AL, Saldana JI, Hager-Theodorides AL, Crompton T (2010) Non-redundant role for the transcription factor Gli1 at multiple stages of thymocyte development. Cell Cycle 9 (20): 4144-52.
Ekeowa-Anderson AL, Purdie KJ, Gibbon K, Byrne CR, Arbeit JM, Harwood CA, O'Shaughnessy RF (2012) AKT1 Loss Correlates with Episomal HPV16 in Vulval Intraepithelial Neoplasia. PLoS One 7(6): e38608.
Findlow H, Borrow R, Andrews N, Waight P, Sheasby E, Matheson M, England A, Goldblatt D, Ashton L, Findlow J, Miller E (2012) Immunogenicity of a single dose of meningococcal group C conjugate vaccine given at 3 months of age to healthy infants in the United kingdom. Pediatr Infect Dis J 31(6): 616-22.
Fujii H, Arakawa A, Kitoh A, Miyara M, Kato M, Kore-Eda S, Sakaguchi S, Miyachi Y, Tanioka M, Ono M (2010) Perturbations of both non-regulatory and regulatory FOXP3(+) T cells in patients with malignant melanoma. Br J Dermatol [Epub ahead of print]
Furmanski AL, O'Shaughnessy RFL, Saldana JI, Blundell MP, Thrasher AJ, Sebire NJ, Davies EG, Crompton T (2013) T-Cell Reconstitution after Thymus Xenotransplantation Induces Hair Depigmentation and Loss. Journal of Investigative Dermatology, In press.
Furmanski AL, Saldana JI, Rowbotham NJ, Ross SE, Crompton T (2012) Role of Hedgehog signalling at the transition from double-positive to single-positive thymocyte. Eur J Immunol 42(2): 489-99.
Furmanski AL, Saldana JI, Rowbotham NJ, Ross SE, Crompton T (2011) Role of Hedgehog signalling at the transition from double-positive to single-positive thymocyte. Eur J Immunol E-Pub
Furmanski AL, Bartok I, Chai JG, Singh Y, Ferreira C, Scott D, Holland SJ, Bourdeaux C, Crompton T, Dyson J (2010) Peptide-specific, TCR-alpha-driven, coreceptor-independent negative selection in TCR alpha-chain transgenic mice. J Immunol 184 (2): 650-7.
Furmanski AL, Crompton T (2009) Shh, BMP4 and IL-7 in the maintenance and differentiation of human CD34+ progenitor cells in the thymus. Cell Cycle 8 (23): 3810.

Geh JL, Geh VS, Jemec B, Liasis A, Harper J, Nischal KK, Dunaway D (2007) Surgical treatment of periocular hemangiomas: a single-center experience. Plast Reconstr Surg 119 (5): 1553–62.

Goldblatt D, Ashton L, Zhang Y, Antonello J, Marchese RD (2011) Comparison of a New Multiplex Binding Assay versus the Enzyme-Linked Immunosorbent Assay for Measurement of Serotype-Specific Pneumococcal Capsular Polysaccharide IgG. Clin Vaccine Immunol 18(10): 1744-51.
Goldblatt D, Plikaytis BD, Akkoyunlu M, Antonello J, Ashton L, Blake M, Burton R, Care R, Durant N, Feavers I, Fernsten P, Fievet F, Giardina P, Jansen K, Katz L, Kierstead L, Lee L, Lin J, Maisonneuve J, Nahm MH, Raab J, Romero-Steiner S, Rose C, Schmidt D, Stapleton J, Carlone GM (2011) Establishment of a new human pneumococcal standard reference serum, 007sp. Clin Vaccine Immunol 18(10): 1728-36.
Goldblatt D, Southern J, Ashton L, Andrews N, Woodgate S, Burbidge P, Waight P, Miller E (2010) Immunogenicity of a reduced schedule of pneumococcal conjugate vaccine in healthy infants and correlates of protection for serotype 6B in the United Kingdom. Pediatr Infect Dis J 29 (5): 401-5.
Goldblatt D (2008) Bacteria, polysaccharides, vaccines and boosting: measuring and maintaining population immunity. Arch Dis Child 93 (8): 646–7.

Goldblatt D, Southern J, Andrews N, Ashton L, Burbidge P, Woodgate S, Pebody R, Miller E (2009) The immunogenicity of 7-valent pneumococcal conjugate vaccine versus 23-valent polysaccharide vaccine in adults aged 50-80 years. Clin Infect Dis 49 (9): 1318–25.

Gordon AR, Outram SV, Keramatipour M, Goddard CA, Colledge WH, Metcalfe JC, Hager-Theodorides AL, Crompton T, Kemp PR (2008) Splenomegaly and Modified Erythropoiesis in KLF13-/- Mice. J Biol Chem 283 (18): 11897–904.

Hager-Theodorides AL, Furmanski AL, Ross SE, Outram SV, Rowbotham NJ, Crompton T (2009) The Gli3 transcription factor expressed in the thymus stroma controls thymocyte negative selection via Hedgehog-dependent and -independent mechanisms. J Immunol 183 (5): 3023–32.

Hager-Theodorides AL, Rowbotham NJ, Outram SV, Dessens JT, Crompton T (2007) Beta-selection: abundance of TCRbeta-/gammadelta- CD44- CD25- (DN4) cells in the foetal thymus. Eur J Immunol 37 (2): 487–500.

Harfouche C, Filippini S, Gianfaldoni C, Ruggiero P, Moschioni M, Maccari S, Pancotto L, Arcidiacono L, Galletti B, Censini S, Mori E, Giuliani M, Facciotti C, Cartocci E, Savino S, Doro F, Pallaoro M, Nocadello S, Mancuso G, Haston M, Goldblatt D, Barocchi MA, Pizza M, Rappuoli R, Masignani V (2012) RrgB321, a Fusion Protein of the Three Variants of the Pneumococcal Pilus Backbone RrgB, Is Protective In Vivo and Elicits Opsonic Antibodies. Infect Immun 80(1): 451-60.
Harper JI, Godwin H, Green A, Wilkes LE, Holden NJ, Moffatt M, Cookson WO, Layton G, Chandler S. (2010) A study of matrix metalloproteinase expression and activity in atopic dermatitis using a novel skin wash sampling assay for functional biomarker analysis. Br J Dermatol 162 (2): 397-403.
Harris SL, Tsao H, Ashton L, Goldblatt D, Fernsten P (2007) Avidity of the immunoglobulin G response to a Neisseria meningitidis group C polysaccharide conjugate vaccine as measured by inhibition and chaotropic enzyme-linked immunosorbent assays. Clin Vaccine Immunol 14 (4): 397–403.

Hoey SE, Eastwood D, Monsell F, Kangesu L, Harper JI, Sebire NJ (2008) Histopathological features of Proteus syndrome. Clin Exp Dermatol 33 (3): 234–8.

Howell KJ, Lavorato A, Visentin MT, Smith RE, Schaefer G, Jones CD, Weibel L, Denton CP, Harper JI, Woo P (2009) Validation of a protocol for the assessment of skin temperature and blood flow in childhood localised scleroderma. Skin Res Technol 15 (3): 346–56.

Hughes SM, Amadi B, Mwiya M, Nkamba H, Mulundu G, Tomkins A, Goldblatt D (2009) CD4 counts decline despite nutritional recovery in HIV-infected Zambian children with severe malnutrition. Pediatrics 123 (2): e347–51.

Hughes SM, Amadi B, Mwiya M, Nkamba H, Tomkins A, Goldblatt D (2009) Dendritic cell anergy results from endotoxemia in severe malnutrition. J Immunol 183 (4): 2818–26.

Jackson B, Brown SJ, Avilion AA, Sully K, O’Shaughnessy RFL, Murphy M, Ambrus M, Cleary ML, Byrne C (2011) TALE homeodomain proteins regulate body site-specific epidermal terminal differentiation and skin barrier. J Cell Sci 124 (10): 1681-90.
Jones H E, Strid J, Osman M, Uronen-Hansson H, Dixon G, Klein N, Wong S Y, Callard R E (2008) The role of beta2 integrins and lipopolysaccharide-binding protein in the phagocytosis of dead Neisseria meningitidis. Cell Microbiol 10: 1634–45.

Jones HE, Uronen-Hansson H, Callard RE, Klein N, Dixon GL (2007) The differential response of human dendritic cells to live and killed Neisseria meningitidis. Cell Microbiol 9 (12): 2856–69.

Jones LB, McGrogan P, Flood TJ, Gennery AR, Morton L, Thrasher A, Goldblatt D, Parker L, Cant AJ (2008) Special article: chronic granulomatous disease in the United Kingdom and Ireland: a comprehensive national patient-based registry. Clin Exp Immunol 152 (2): 211–8.

Kakourou G, Dhanjal S, Daphnis D, Doshi A, Nuttall S, Gotts S, Serhal P, Delhanty J, Harper J, SenGupta S (2007) Preimplantation genetic diagnosis for myotonic dystrophy type 1: detection of crossover between the gene and the linked marker APOC2. Prenat Diagn 27 (2): 111–6.

Kinsler VA, Birley J, Atherton DJ (2009) Great Ormond Street Hospital for Children Registry for congenital melanocytic naevi: prospective study 1988-2007. Part 1-epidemiology, phenotype and outcomes. Br J Dermatol 160 (1): 143–50.

Kinsler VA, Birley J, Atherton DJ (2009) Great Ormond Street Hospital for Children Registry for Congenital Melanocytic Naevi: prospective study 1988-2007. Part 2--Evaluation of treatments. Br J Dermatol 160 (2): 387–92.

Lau CI, Outram SV, Ignacio SJ, Furmanski AL, Dessens JT, Crompton T (2012) Regulation of murine normal and stress-induced erythropoiesis by Desert Hedgehog. Blood 119(20): 4741-51.
Lewis J, Walker AS, Castro H, De RA, Gibb DM, Giaquinto C, Klein N, Callard R (2012) Reply to zhang, poznansky, and crumpacker. J Infect Dis 206(4): 618.
Lewis J, Walker AS, Castro H, De RA, Gibb DM, Giaquinto C, Klein N, Callard R (2012) Age and CD4 Count at Initiation of Antiretroviral Therapy in HIV-Infected Children: Effects on Long-term T-Cell Reconstitution. J Infect Dis 205(4): 548-56.
Lewis J, Walker AS, Klein N, Callard R (2012) CD31+ Cell Percentage Correlation With Speed of CD4+ T-Cell Count Recovery in HIV-Infected Adults Is Reversed in Children: Higher Thymic Output May Be Responsible. Clin Infect Dis 55(2): 304-7.
Maione F, Paschalidis N, Iqbal AJ, Crompton T, Perretti M, D'Acquisto F (2010) Analysis of the inflammatory response in HY-TCR transgenic mice highlights the pathogenic potential of CD4(- )CD8(- ) T cells. Autoimmunity 43 (8): 672-81.
Manunza F, Syed S, Laguda B, Linward J, Kennedy H, Gholam K, Glover M, Giardini A, Harper JI (2010) Propranolol for complicated infantile haemangiomas: a case series of 30 infants. Br J Dermatol 162 (2): 466-8.
Mazereeuw-Hautier J, Bitoun E, Chevrant-Breton J, Man SY, Bodemer C, Prins C, Antille C, Saurat JH, Atherton D, Harper JI, Kelsell DP, Hovnanian A (2007) Keratitis-ichthyosis-deafness syndrome: disease expression and spectrum of connexin 26 (GJB2) mutations in 14 patients. Br J Dermatol 156 (5): 1015–9.

Mazereeuw-Hautier J, Syed S, Leisner RI, Harper JI (2007) Extensive venous/lymphatic malformations causing life-threatening haematological complications. Br J Dermatol 157 (3): 558–63.

Mazereeuw-Hautier J, Wilson LC, Mohammed S, Smallwood D, Shackleton S, Atherton DJ, Harper JI (2007) Hutchinson-Gilford progeria syndrome: clinical findings in three patients carrying the G608G mutation in LMNA and review of the literature. Br J Dermatol 156 (6): 1308–14.

McNally L, Jeena P, Tomkins A, Coovadia H, Goldblatt D (2007) WHO guidelines for treatment of severe pneumonia - Authors' reply. Lancet 370 (9585): 385–6.

McNally LM, Jeena PM, Gajee K, Thula SA, Sturm AW, Cassol S, Tomkins AM, Coovadia HM, Goldblatt D (2007) Effect of age, polymicrobial disease, and maternal HIV status on treatment response and cause of severe pneumonia in South African children: a prospective descriptive study. Lancet 369 (9571): 1440–51.

Miller E, Andrews N, Waight P, Findlow H, Ashton L, England A, Stanford E, Matheson M, Southern J, Sheasby E, Goldblatt D, Borrow R (2011) Safety and immunogenicity of co-administering a combined meningococcal serogroup C and Haemophilus influenzae type b conjugate vaccine with 7-valent pneumococcal conjugate vaccine and measles, mumps and rubella vaccine at 12 months of age. Clin Vaccine Immunol 18 (3): 367-72.
Montano X (2009) Repression of SHP-1 expression by p53 leads to trkA tyrosine phosphorylation and suppression of breast cancer cell proliferation. Oncogene 28 (43): 3787–800.

Moore SE, Richards AA, Goldblatt D, Ashton L, Szu SC, Prentice AM (2012) Early-life and contemporaneous nutritional and environmental predictors of antibody response to vaccination in young Gambian adults. Vaccine 30(32): 4842-8.
Morar N, Cookson WO, Harper JI, Moffatt MF (2007) Filaggrin mutations in children with severe atopic dermatitis. J Invest Dermatol 127 (7): 1667–72.

O'Brien KL, Hochman M, Goldblatt D (2007) Combined schedules of pneumococcal conjugate and polysaccharide vaccines: is hyporesponsiveness an issue?. Lancet Infect Dis 7 (9): 597–606.

Oduber CE, van dHCM, Sillevis SJH, Smeulders MJ, Mendiratta V, Harper JI, van SMA, Hennekam RC (2011) A proposal for classification of entities combining vascular malformations and deregulated growth. Eur J Med Genet 54(3): 262-71.
Ono M, Tanaka RJ, Kano M, Sugiman T (2013) Visualising the Cross-Level Relationships between Pathological and Physiological Processes and Gene Expression: Analyses of Haematological Diseases. PLoS ONE 8(1):e53544.
Ono M (2011) Ethics should trump science in Fukushima. Bmj 342: d3853.
O'Shaughnessy RF, Choudhary I, Harper JI (2010) Interleukin-1 alpha blockade prevents hyperkeratosis in an in vitro model of lamellar ichthyosis. Hum Mol Genet 19(13): 2594-605.
O'Shaughnessy RF, Welti JC, Sully K, Byrne C (2009) Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development. Development 136 (20): 3423–31.

Ota MO, Akinsola A, Townend J, Antonio M, Enwere G, Nsekpong D, Bojang A, Saaka M, Burton RL, Zaman A, Goldblatt D, Adegbola RA (2011) The immunogenicity and impact on nasopharyngeal carriage of fewer doses of conjugate pneumococcal vaccine immunization schedule. Vaccine 29(16): 2999-3007.
Outram SV, Gordon AR, Hager-Theodorides AL, Metcalfe J, Crompton T, Kemp P (2008) KLF13 influences multiple stages of both B and T cell development. Cell Cycle 7 (13): 2047–55.

Outram SV, Hager-Theodorides AL, Shah DK, Rowbotham NJ, Drakopoulou E, Ross SE, Lanske B, Dessens JT, Crompton T (2009) Indian hedgehog (Ihh) both promotes and restricts thymocyte differentiation. Blood 113 (10): 2217–28.

Paschalidis N, Huggins A, Rowbotham NJ, Furmanski AL, Crompton T, Flower RJ, Perretti M, D'Acquisto F (2010) Role of endogenous annexin-A1 in the regulation of thymocyte positive and negative selection. Cell Cycle 9 (4): 784-93.

Ponnampalam J, Nicholson J, Atherton D (2007) Leptomeningeal melanoma and multiple cutaneous melanocytic naevi. Br J Dermatol 157 (2): 397–398.

Purvis DJ, Bhogal BS, Harper JI (2009) Bullous pemphigoid in an infant using complementary medicine. Clin Exp Dermatol 34 (2): 195–8.

Remitz A, Harper J, Rustin M, Goldschmidt WF, Palatsi R, van der Valk PG, Sharpe G, Smith CH, Dobozy A, Turjanmaa K, European Tacrolimus Ointment Study Group (2007) Long-term safety and efficacy of tacrolimus ointment for the treatment of atopic dermatitis in children. Acta Derm Venereol 87 (1): 54–61.

Rodgers W, Ancliff P, Ponting CP, Sanchez-Pulido L, Burns S, Hayman M, Kimonis V, Sebire N, Bulstrode N, Harper JI: Squamous cell carcinoma in a child with Clericuzio-type poikiloderma with neutropenia. Br J Dermatol 2012.
Rose CE, Romero-Steiner S, Burton RL, Carlone GM, Goldblatt D, Nahm MH, Ashton L, Haston M, Ekström N, Haikala R, Käyhty H, Henckaerts I, Durant N, Poolman JT, Fernsten P, Yu X, Hu BT, Jansen KU, Blake M, Simonetti ER, Hermans PW, Plikaytis BD (2011) Multilaboratory Comparison of Streptococcus pneumoniae Opsonophagocytic Killing Assays and Their Level of Agreement for the Determination of Functional Antibody Activity in Human Reference Sera. Clin Vaccine Immunol 18 (1): 135-42.

Rowbotham NJ, Furmanski AL, Hager-Theodorides AL, Ross SE, Drakopoulou E, Koufaris C, Outram SV, Crompton T (2008) Repression of hedgehog signal transduction in T-lineage cells increases TCR-induced activation and proliferation. Cell Cycle 7 (7): 904–8.

Rowbotham NJ, Hager-Theodorides AL, Cebecauer M, Shah DK, Drakopoulou E, Dyson J, Outram SV, Crompton T (2007) Activation of the Hedgehog signaling pathway in T-lineage cells inhibits TCR repertoire selection in the thymus and peripheral T-cell activation. Blood 109 (9): 3757–66.

Rowbotham NJ, Hager-Theodorides AL, Furmanski AL, Crompton T (2007) A novel role for Hedgehog in T-cell receptor signaling: implications for development and immunity. Cell Cycle 6 (17): 2138–42.

Rowbotham NJ, Hager-Theodorides AL, Furmanski AL, Ross SE, Outram SV, Dessens JT, Crompton T (2009) Sonic hedgehog negatively regulates pre-TCR-induced differentiation by a Gli2-dependent mechanism. Blood 113 (21): 5144–56.

Saaka M, Okoko BJ, Kohberger RC, Jaffar S, Enwere G, Biney EE, Oluwalana C, Vaughan A, Zaman SM, Asthon L, Goldblatt D, Greenwood BM, Cutts FT, Adegbola RA (2008) Immunogenicity and serotype-specific efficacy of a 9-valent pneumococcal conjugate vaccine (PCV-9) determined during an efficacy trial in The Gambia. Vaccine 26 (29-30): 3719–26.

Scott JA, Ojal J, Ashton L, Muhoro A, Burbidge P, Goldblatt D (2011) Pneumococcal Conjugate Vaccine given shortly after birth stimulates effective antibody concentrations and primes immunological memory for sustained infant protection. Clinical Infectious Disease 53 (7):663-70.
Scott CA, Plagnol V, Nitoiu D, Bland PJ, Blaydon DC, Chronnell CM, Poon DS, Bourn D, Gardos L, Csaszar A, et al.: Targeted Sequence Capture and High-Throughput Sequencing in the Molecular Diagnosis of Ichthyosis and Other Skin Diseases. J Invest Dermatol 2012.
Scott CA, Rajpopat S, Di WL: Harlequin ichthyosis: ABCA12 mutations underlie defective lipid transport, reduced protease regulation and skin-barrier dysfunction. Cell Tissue Res 2012.
Shah V, Shah S, Barnacle A, Sebire NJ, Brock P, Harper JI, McHugh K (2011) Mediastinal involvement in lymphangiomatosis: a previously unreported MRI sign. Pediatr Radiol 41 (8):985-92.
Simell B, Auranen K, Kayhty H, Goldblatt D, Dagan R, O'Brien KL: The fundamental link between pneumococcal carriage and disease. Expert Rev Vaccines 2012, 11:841-855.
Smith CM, Lo Passo C, Scuderi A, Kolberg J, Baxendale H, Goldblatt D, Oggioni MR, Felici F, Andrew PW (2009) Peptide mimics of two pneumococcal capsular polysaccharide serotypes (6B and 9V) protect mice from a lethal challenge with Streptococcus pneumoniae. Eur J Immunol 39 (6): 1527–35.

Southern J, McVernon J, Gelb D, Andrews N, Morris R, Crowley-Luke A, Goldblatt D, Miller E (2007) Immunogenicity of a fourth dose of Haemophilus influenzae type b (Hib) conjugate vaccine and antibody persistence in young children from the United Kingdom who were primed with acellular or whole-cell pertussis component-containing Hib combinations in infancy. Clin Vaccine Immunol 14 (10): 1328–33.

Steeghs L, Keestra AM, van Mourik A, Uronen-Hansson H, van der Ley P, Callard R, Klein N, van Putten JP (2008) Differential activation of human and mouse Toll-like receptor 4 by the adjuvant candidate LpxL1 of Neisseria meningitidis. Infect Immun 76 (8): 3801–7.

Strid J, Tan LA, Strobel S, Londei M, Callard R (2007) Epicutaneous immunization with type II collagen inhibits both onset and progression of chronic collagen-induced arthritis. PLoS ONE 2: e387.

Sully K, Akinduro O, Philpott MP, Naeem AS, Harwood CA, Reeve VE, O'Shaughnessy RF, Byrne C: The mTOR inhibitor rapamycin opposes carcinogenic changes to epidermal Akt1/PKBalpha isoform signaling. Oncogene 2012.
Syed S, Weibel L, Kennedy H, Harper JI (2008) A pilot study showing pulsed-dye laser treatment improves localized areas of chronic atopic dermatitis. Clin Exp Dermatol 33 (3): 243–8.

Tanaka RJ, Ono M, Harrington HA (2011) Skin barrier homeostasis in atopic dermatitis: feedback regulation of kallikrein activity. PLoS One 6(5): e19895.
Thomas AC, Sinclair C, Mahmud N, Cullup T, Mellerio JE, Harper J, Dale BA, Turc-Carel C, Hohl D, McGrath JA, Vahlquist A, Hellstrom-Pigg M, Ganemo A, Metcalfe K, Mein CA, O'Toole EA, Kelsell DP (2008) Novel and recurring ABCA12 mutations associated with harlequin ichthyosis: implications for prenatal diagnosis. Br J Dermatol 158 (3): 611–613.

Trotter C L, McVernon J, Ramsay M E, Whitney C G, Mulholland E K, Goldblatt D, Hombach J, Kieny M P (2008) Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae. Vaccine 26: 4434–4445.

Turner C, Turner P, Cararra V, Eh Lwe N, Watthanaworawit W, Day NP, White NJ, Goldblatt D, Nosten F (2012) A high burden of respiratory syncytial virus associated pneumonia in children less than two years of age in a South East asian refugee population. PLoS One 7:e50100.
Turner P, Turner C, Jankhot A, Helen N, Lee SJ, Day NP, White NJ, Nosten F, Goldblatt D (2012) A Longitudinal Study of Streptococcus pneumoniae Carriage in a Cohort of Infants and Their Mothers on the Thailand-Myanmar Border. PLoS One 7(5): e38271.
Turner P, Melchiorre S, Moschioni M, Barocchi MA, Turner C, Watthanaworawit W, Kaewcharernnet N, Nosten F, Goldblatt D Assessment of Streptococcus pneumoniae pilus islet-1 prevalence in carried and transmitted isolates from mother-infant pairs on the Thailand-Burma border. Clin Microbiol Infect  2012, 18:970-975.
Turner P, Hinds J, Turner C, Jankhot A, Gould K, Bentley S, Nosten F, Goldblatt D (2011) Improved detection of nasopharyngeal co-colonization by multiple pneumococcal serotypes using latex agglutination or molecular serotyping by microarray. J Clin Microbiol 49(5): 1784-9.
Turner P, Po L, Turner C, Goldblatt D, Nosten F (2011) Detection of respiratory viruses by PCR of nasopharyngeal swabs stored in skim milk-tryptone-glucose-glycerol transport medium. J Clin Microbiol 49(6): 2311-3.
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