Clinical & Molecular Genetics Unit
(Part of the Genes, Development & Disease Theme)
The Clinical and Molecular Genetics Unit (CMGU) comprises a critical mass of more than 50 clinical and basic science staff with a common interest in the genetic and epigenetic regulation of human development and disease.
Our goals are to:
- Understand the molecular, genetic and developmental aetiology of a range of single gene disorders, syndromes and complex traits in humans
- Develop new tests for diagnosing and monitoring these conditions
- Translate our research findings into improved care for children, adults and families
The CMGU is led by Professor Gudrun Moore and developed into its current structure following the merger of Clinical & Molecular Genetics with Biochemistry, Endocrinology & Metabolism in 2006.
Although specific research areas across the Unit are disorder-diverse, the common goals of the Unit are reflected within all the research groups. Consequently, new research technologies and insights into disease mechanisms can be readily shared between investigators and their teams.
In parallel with our research teams, we have highly productive and efficient DNA and Cytogenetics diagnostic laboratories; close links with the internationally renowned Clinical Genetics Service at GOSH and North Thames (East) Clinical Genetics Service; and associations with the specialist biochemical, metabolic and enzyme laboratory services at GOSH and Fetal Medicine Unit at UCLH.
- Clinical Genetics: The Regional Genetics Service: Led by Angela Barnicoat
- Chemical Pathology: Led by Simon Heales
- Molecular Genetic Diagnostic Services: Led by Nick Lench
- Cytogenetics Diagnostic Services: Led by Nick Lench
- Clinical Metabolic Research: jointly led by Maureen Cleary/Ashok Vellodi
Many of the staff in CMGU have joint clinical and academic appointments, highlighting the translational nature of much of the work undertaken in the unit.
Page last modified on 07 mar 13 20:42