UCL Great Ormond Street Institute of Child Health


ICH News

Dr Manju Kurian wins the 2017 Sir Jules Thorn Award for Biomedical Research

The UCL Great Ormond Street Institute of Child Health is delighted to announce that Dr Manju Kurian has been awarded the 2017 Sir Jules Thorn Award for Biomedical Research.  The Sir Jules Thorn Charitable Trust offers one grant annually of up to £1.5 million to support a programme of translational research for up to 5 years.  Applicants for this prestigious award must be sponsored by a leading UK medical school or NHS organisation, and each institution is restricted to submitting one application per year.  This award of nearly £1.5 million will support Dr Kurian’s work investigating genetic movement disorders that mimic Cerebral Palsy (CP). Her project aims to improve treatments for her patients by developing therapies that target specific genetic defects.

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Dr Owen Arthurs awarded NIHR Career Development Fellowship

We are delighted to announce that Dr Owen Arthurs has been awarded a Career Development Fellowship (CDF) from the National Institute for Health Research (NIHR).  The NIHR CDF awards are made to researchers with a proven track-record at postdoctoral level, and provide up to 5 years’ funding to support their development into fully independent group leaders within their designated field of research.  Dr Arthurs, Consultant Paediatric Radiologist at GOSH and Honorary Senior Lecturer at the UCL Great Ormond Street Institute of Child Health, is one of only four NIHR CDFs awarded this year and this award continues from his successful NIHR Clinician Scientist award.

This NIHR CDF award, entitled “Next generation perinatal autopsy: changing death investigation through imaging-based less invasive autopsy” allows Dr Arthurs to continue his work developing post mortem imaging as an alternative to autopsy for children. This key area of research aims to bring post mortem imaging techniques into standard clinical practice, to help families during pregnancy loss or childhood bereavement to understand why their baby or child has died. Although GOSH runs the largest perinatal autopsy service nationally, many parents do not feel that a traditional invasive autopsy is appropriate for them. Imaging offers a non-invasive way of diagnosing congenital abnormalities which can help to counsel parents about why their child died, and whether subsequent pregnancies or other existing children might be affected.

Over the course of this NIHR fellowship, novel imaging techniques such as microCT (see figure) will be assessed and developed into clinical practice within the next 3-5 years, and national and international clinical guidelines will be designed for an evidence-based patient-centered approach to death investigation. Dr Arthurs, who also leads Research and Innovation within GOSH Radiology, commented “I am delighted that the advanced imaging within UCL GOS ICH plays an increasing important diagnostic role in important childhood diseases”.

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£5m government investment in new childhood Obesity Policy Research Unit

The UCL Great Ormond Street Institute of Child Health is pleased to announce a £5 million investment from the Department of Health in a new National Institute for Health Research (NIHR) Research Policy Unit to develop a deeper understanding on the causes of childhood obesity. 

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Senior Promotions 2016-17

We are very proud to announce the following senior promotions of colleagues, effective from 1st October:

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L'Oreal-UNESCO Women in Science 2017 winner - Dr Manju Kurian

Dr Manju Kurian, of the Developmental Neurosciences programme at Great Ormond Street Institute of Child Health, is among five promising UK scientists who won prestigious fellowships at the 10th annual L’Oréal-UNESCO UK and Ireland For Women In Science. 

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Genetic screening service enables PCD gene discovery

A team at UCL Great Ormond Street Institute of Child Health and University College London working with the Royal Brompton Hospital have identified a new gene which causes the lung condition Primary Ciliary Dyskinesia (PCD). Working with researchers from around Europe including hospitals in Italy, Switzerland and France, the team have shown that the condition can be 'X-linked' meaning it is passed from mothers to their sons.

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Gene key for chemically reprogramming human stem cells

Scientists have discovered the gene essential for chemically reprogramming human amniotic stem cells into a more versatile state similar to embryonic stem cells, in research led by UCL and Heinrich Heine University.

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Children’s charities join forces to boost research into childhood diseases

Children’s medical research charity Sparks has announced today (Monday 23rd January 2017) that it will be joining Great Ormond Street Hospital Children’s Charity in a partnership which will result in an increase in funding for pioneering and life-changing child health research.

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Cells from pregnant women could prevent fractures by nearly 80 per cent for millions with fragile bones

Injecting cells from pregnant women could have a life-changing effect on the millions who are living with osteoporosis and brittle bone disease according to researchers at the UCL GOS Institute of Child Health, the research partner of Great Ormond Street Hospital and The UCL Institute for Women’s Health. These cells could also be useful for strengthening the fragile bones of astronauts during their stay for long periods in space. 

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Remarkable recovery in patients diagnosed with newly defined movement disorder

Researchers from the UCL GOS Institute of Child Health have discovered a new gene change that identifies a type of the movement disorder, muscle dystonia. This new discovery will allow doctors to more easily identify patients who can benefit from treatment so effective that it can restore the ability to walk.

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Vitamin B6 is lifesaver for children with severe epilepsy

Children with severe epilepsy who do not respond to traditional drugs could be treated with vitamin B6, after the discovery of a new gene by UCL Great Ormond Street Institute of Child Health (ICH) and its clinical partner Great Ormond Street Hospital (GOSH).

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€7 million EU Horizon2020 Award for ZIKAction

€7 million EU Horizon2020 Award for ZIKAction: Preparedness, research and action network on maternal-paediatric axis of ZIKV infection in Latin America and the Caribbean.

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Accelerated approval granted for new drug for muscular dystrophy

The prospect of widespread access to a life-changing drug for children with a rare muscular disorder is a step closer today after the United States Food and Drug Administration (FDA) granted accelerated approval for a new medication.

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Visual health linked to social position

A new research study from the UCL Institute of Child Health, Great Ormond Street Hospital’s research partner, shows that poor visual health is associated with poorer social, economic, educational, and employment opportunities and outcomes.

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Senior Promotions 2015-16

We are very proud to announce the following senior promotions of Institute colleagues, effective from 1st October:

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