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Cancer drugs could transform the lives of children with serious facial disfigurements

21 February 2018

Veronica Kinsler Research

Drugs normally used to treat cancer could reduce the facial disfigurements of thousands of children born with life-threatening blood vessel defects, according to research by Great Ormond Street Hospital (GOSH) and its academic partner, the UCL Great Ormond Street Institute of Child Health (ICH).

Following DNA testing, scientists have been able to pinpoint the group of genes responsible for causing blood vessel defects in Arteriovenous Malformation (AVM). And for the first time, they have identified drugs which could target the underlying cause of the condition.


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