Papers of the month, April 2014

We are featuring two outstanding papers this month by researchers at the UCL Institute of Child Health (ICH) :

The first paper is with Dr Khalid Hussain as lead author, which reports to use of a new agent called sirolimus in four patients with severe hyperinsulinemic hypoglycemia for whom the only alternative option would have been subtotal pancreatectomy. All patients had a good improvement in their hypoglycemia in response to this treatment with no major adverse effects.

The second paper is from Dr Claire Townsend, Dr Mario Cortina- Borja, Dr Claire Thorne, Professor Catherine Peckham and Professor Pat Tookey which was published in AIDS and presents definite evidence that mother to child transmission of HIV rates in the UK and Ireland have reached an all-time low of 5 per 1,000 births in 2000 to 20111, which is a very substantial reduction.