Monday 17 June 2013
Time: 1.00-2.00pm (tea/coffee available from 12.40pm)
Kennedy Lecture Theatre, UCL Institute of Child Health.
If you would like to suggest someone as a speaker, please contact the OWL Committee Chair, Professor Christine Kinnon.
For any administrative questions, please contact Nicole Hofmans.
Making cells make mesoderm
Part of the Otto Wolff Lecture series 2013
Dr Jim Smith
Director, MRC National Institute for Medical Research (NIMR)
Members of the T-box family of transcription factors are both necessary and sufficient for proper mesoderm formation in the vertebrate embryo. Here I describe how T-box genes are activated and how T-box proteins exert their effects. I conclude that T-box proteins regulate the fate of neuro-mesodermal stem cells present in the tail-bud of the developing embryo.
Jim Smith is Director of the Medical Research Council’s National Institute for Medical Research (NIMR), a post he took up in 2009. He was previously Professor of Developmental Biology and Director of the Gurdon Institute at the University of Cambridge, and before that had worked at NIMR from 1984 to 2000.
Jim was elected a Fellow of the Royal Society in 1993 and a Fellow of the Academy of Medical Sciences in 1998. He was awarded the EMBO medal in 1994, the Feldberg Foundation Award in 2000, and the Waddington Medal of the British Society for Developmental Biology in 2013.