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Latest Global Health News

Commonly prescribed drugs affect decisions to harm oneself and others

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Pills

Healthy people given the serotonin-enhancing antidepressant citalopram were willing to pay almost twice as much to prevent harm to themselves or others than those given placebo drugs in a moral decision-making experiment at UCL.

Climate change threatens to undermine the last half century of health gains

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Climate emergency

The threat to human health from climate change is so great that it could undermine the last fifty years of gains in development and global health, according to a major new UCL-led Commission, published in The Lancet.

‘Core’ immune cells reduce symptoms and spread of flu

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H1N1 influenza virus particles shown in transmission electron micrograph

A four-year study of 1,414 unvaccinated people across England found that 43% of them had immune cells that protected them from symptoms of both seasonal and pandemic influenza, and reduced their chances of shedding the virus by two thirds. The work led by researchers from UCL, Oxford University and Public Health England was funded by the Medical Research Council and Wellcome Trust.

Natural genetic variation gives complete resistance in prion diseases

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Prion protein expressed in E. coli

Researchers at the Medical Research Council’s Prion Unit at UCL have identified a naturally occurring variant of the human prion protein that produces resistance to prion diseases such as Creutzfeldt-Jakob disease (CJD). The findings, published in Nature, could give important insight into other human brain diseases that lead to dementia.

New treatment for polycystic kidney disease

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Small vessels inside a cystic kidney with disorganised vasculature

A new technique for treating polycystic kidney disease has been identified by researchers based at the UCL Institute of Child Health. Published in the Journal of the American Society of Nephrology, the treatment, which involves targeting tiny blood and lymphatic vessels inside the kidneys, is shown to improve renal function and slow progression of disease in mice.

Starting HIV treatment early improves patient outcomes

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Scanning electromicrograph of an HIV-infected H9 T cell

A major international randomised clinical trial has found that HIV-infected individuals have a considerably lower risk of developing AIDS or other serious illnesses if they start taking antiretroviral drugs sooner, when their CD4+ T-cell count—a key measure of immune system health—is higher, instead of waiting until the CD4+ cell count drops to lower levels.

Chemo before surgery benefits patients with advanced ovarian cancer

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Chemotherapy machine

Women with advanced ovarian cancer have fewer side effects and tend to have a better quality of life if given chemotherapy before surgery, according to a Cancer Research UK funded study published in The Lancet.

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