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Research at UCL

“UCL is London’s research powerhouse, with a commitment to enhancing the lives of people in the capital, the UK and around the world. Our academics have breadth and depth of expertise across the entire range of academic disciplines. Individually, they expand our understanding of the world; collectively and collaboratively, they deliver analysis that addresses the major challenges facing humanity.”
– Professor David Price, UCL Vice-Provost (Research)

Research at GEE

The Research Department of Genetics, Evolution and Environment (GEE) brings together scientists with shared interests in evolutionary, population and environmental biology, genetics, systems biology, theoretical biology and human genetics and evolution. GEE traces its origins to the Department of Comparative Anatomy, founded in 1826 and the first in Britain to offer a Zoology degree. It also incorporates the former Galton Laboratory, the first institution in the world to study human genetics as a science. Some great scientific figures of the past associated with the Department - whose own building stands on the site of Charles Darwin's London home - include Robert Grant (who taught Darwin in Edinburgh and whose extraordinary collection of animal specimens we still possess), Sir Francis Galton (Darwin's cousin, and the founder of the modern study of human genetics, who left a large sum to establish the Galton Laboratory), Karl Pearson and R. A. Fisher (jointly the founders of modern statistical science), J. B. S. Haldane (who placed the theory of evolution on a mathematical basis), John Maynard Smith and W. D. Hamilton (pioneers of modern evolutionary theory). More information on our history.

Research Themes

The Department currently comprises getting on for 50 members of academic staff, 70 postdoctoral researchers and 80 graduate students. The Department has recently moved into new laboratories in a £5.5 million refurbishment of the Darwin Building on Gower Street in the heart of the Bloomsbury campus. Research in the Department falls under a number of overlapping themes. Please click on the headings below to explore our work and the research interests of individual staff members.

Biodiversity and Environmental Biology

down_arrow.gif Biodiversity and Environmental Biology
 

Helen Chatterjee: phylogenetics, morphometrics, biogeography, conservation, niche modelling, mammals

Julia Day: systematics, molecular phylogenetics, speciation, Great African lakes, fish

Ben Collen:  biodiversity, abundance, extinction risk, ecology

Anjali Goswami: evolution, morphometrics, mammals

Kate Jones:  biodiversity, ecology, wildlife epidemiology

Georgina Mace:  biodiversity, ecology

David Murrell: biodiversity, ecology, modelling, plants

Richard Pearson:  biodiversity, biogeography, conservation biology

Astrid Wingler: plant biology, plant metabolism, senescence, stress response

See also Centre for Biodiversity & Environment Research

Biology of Ageing

 

Nazif Alic: ageing, transcriptional regulation, Drosophila melanogaster

Jürg Bähler:genome regulation, yeast, gene expression, genetic variability and networks

Lazaros Foukas: cell signalling, metabolic regulation, mammalian ageing, age-related disease

David Gems: ageing, worms

Linda Partridge: evolutionary genomics, genetics of ageing, Drosophila

Daniel Pearce: stem cells, ageing

Matt Piper: ageing, nutrition, behaviour, drosophila

Eugene Schuster: gene regulation, genomics, ageing

Astrid Wingler: Plant biology; plant metabolism; senescence. stress response

See also Institute of Healthy Ageing

Computational Biology

 

Jürg Bähler:genome regulation, yeast, gene expression, genetic variability and networks

Francois Balloux: computational biology, systems biology

David Balding: Statistical genetics, genetic epidemiology, forensic DNA profiles, population genetics

Oliver Davis: statistical genetics, behavioural genetics, human genetic and environmental epidemiology, data visualisation, data science

Christophe Dessimoz:  comparative genomics, phylogenetics, sequence analysis, gene function, gene ontology, molecular evolution

Richard Goldstein:

Daniel Jeffares: schizosaccharomyces pombe, fission yeast, transcriptome, long non-coding RNAs, population genomics

Nicholas Luscombe: Bioinformatics, computational biology, gene expression profiling, genomics

Nikolas Maniatis: human genetics, linkage disequilibrium in human diseases

Judith Mank:  Systems Biology; Evolutionary Genetics

David Murrell: biodiversity, ecology, plants

Vincent Plagnol: statistical genetics, human disease

Andrew Pomiankowski: sexual selection; genomic imprinting; gene networks; evolutionary genomics

Max Reuter: phenotypic and genomic evolution; gene expression; fruit fly

Mark Thomas: human evolution, cultural evolution, human genetics, population genetics, lactase persistence, evolutionary genetics

Ziheng Yang: statistical genetics; molecular evolution; population genetics; phylogenetics

See also:

CoMPLEX

RA Fisher Centre for Computational Biology

Evolutionary Genetics

 

Jürg Bähler:genome regulation, yeast, gene expression, genetic variability and networks

Francois Balloux: computational biology, systems biology

Julia Day: systematics, molecular phylogenetics, speciation, African Great lakes, fish

Kevin Fowler: evolution, quantitative genetics, insect systems, stalk-eyed flies

Duncan Greig: evolutionary genetics, cooperation, sexual selection, yeast

Steve Jones: evolution, evolutionary genetics, snail genetics, thermal ecology

Nick Lane: mitochondria evolutionary biochemistry, bioenergetics, cell biology, mitochondria

Linda Partridge: evolutionary genomics, genetics of ageing, Drosophila

Vincent Plagnol: human genetics, high throughput DNA sequencing, autoimmunity

Andrew Pomiankowski: sexual selection, genomic imprinting, gene networks, evolutionary genomics

Max Reuter: phenotypic and genomic evolution, gene expression, fruitfly

Mark Thomas: human evolution, cultural evolution, human genetics, population genetics, lactase persistence, evolutionary genetics

Ziheng Yang: statistical genetics, molecular evolution, population genetics, phylogenetics

Evolution and Development

 

Nazif Alic: ageing, transcriptional regulation, Drosophila melanogaster

Jürg Bähler:genome regulation, yeast, gene expression, genetic variability and networks

Helen Chatterjee: mammalian evolution, phylogenetics, morphometrics, biogeography, conservation, niche modelling

Christophe Dessimoz: comparative genomics, phylogenetics, sequence analysis, gene function, gene ontology, molecular evolution

David Gems: ageing, worms

Anjali Goswami: mammalian evolution, morphometrics

Nick Lane: mitochondria evolutionary biochemistry, bioenergetics, cell biology, mitochondria

Nicholas Luscombe: Bioinformatics, computational biology, gene expression profiling, genomics

Paola Oliveri: evo-devo, gene networks, sea urchin

Linda Partridge: evolutionary genomics, genetics of ageing, Drosophila

Daniel Pearce: ageing, stem cells

Nichola Raihani:cooperation, social evolution, punishment, partner choice

Eugene Schuster: gene regulation, ageing, functional genomics, bioinformatics

Hazel Smith: evolution of development, stalk-eyed flies, fish

Max Telford: biodiversity, evolution, evo-devo, phylogenetics

Astrid Wingler: plant biology, plant metabolism, senescence, stress response

Genome Regulation

 

Nazif Alic: ageing, transcriptional regulation, Drosophila melanogaster

Jürg Bähler:genome regulation, yeast, gene expression, genetic variability and networks

Lazaros Foukas:  cell signalling, metabolic regulation, mammalian ageing, age-related disease

David Gems: ageing, worms

Judith Mank: computational biology; evolutionary genetics

Nicholas Luscombe: Bioinformatics, computational biology, gene expression profiling, genomics

Paola Oliveri: evo-devo, gene networks, sea urchin

Linda Partridge: evolutionary genomics, genetics of ageing, Drosophila

Matt Piper: ageing, nutrition, behaviour, drosophila

Max Reuter: phenotypic and genomic evolution, gene expression, fruitfly

Eugene Schuster: gene regulation, ageing, functional genomics, bioinformatics

Astrid Wingler: plant biology, plant metabolism, senescence, stress response

   

Human Genetics and Human Evolution

 

David Balding: Statistical genetics, genetic epidemiology, forensic DNA profiles, population genetics

Oliver Davis: statistical genetics, behavioural genetics, human genetic and environmental epidemiology, data visualisation, data science

Garrett Hellenthal:population genetics, statistical genetics, human genetics, modelling linkage disequilibrium

Steve Humphries:

Steve Jones: evolution, evolutionary genetics, snail genetics, thermal ecology

Nicholas Luscombe: Bioinformatics, computational biology, gene expression profiling, genomics

James MacKay: human cancer genetics

Nik Maniatis: human genetics, linkage disequilibrium in human diseases

Vincent Plagnol: human genetics, high throughput DNA sequencing, autoimmunity

Sue Povey: human genetics

Andres Ruiz-Linares: human genetic variation, human disease

Dallas Swallow: human genetics, functional variation, regulatory variation, epithelial proteins, lactase persistence, population genetics

Mark Thomas: human evolution, cultural evolution, human genetics, population genetics, lactase persistence, evolutionary genetics

Nick Wood: human genetics, neurology

See also UCL Genetics Institute

Research Centres

Departmental staff are involved in a variety of cross-departmental groupings with members from the Division of Biosciences, the Department of Medical Sciences, Mathematics, Statistics, Computer Science and Physics, and other London based institutes like the Natural History Museum, the Royal Botanic Gardens and the Institute of Zoology. They include the:

Institute of Healthy Ageing (Director Professor Dame Linda Partridge, FRS),

R. A. Fisher Centre of Computational Biology (Director, Professor Ziheng Yang, FRS),

Centre for Biodiversity and Environmental Research (Director, Professor Georgina Mace, FRS)

UCL Genetics Institute (Director, Professor Steve Humphries).

The Department has great strength in Evolutionary Genetics, Evolution and Development, as well as Human Evolution. See Research Centres for a full list of these and others, and a brief description of their activities.

Research Services

See the list of the main research services provided within GEE and by the School of Life and Medical Sciences.

Page last modified on 29 jul 14 13:19