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Sex Differentiation Begins During Early Development

Wed, 27 Aug 2014 14:04:57 +0000

Males and females look different from each other, and these sexual dimorphisms are the result, largely, of sex differences in the expression of certain genes. Typically, scientists have studied sexual dimorphism in sexually mature adult animals, as this is the lifestage where differences are most apparent. However, many sex-specific phenotypes arise from sex-biased development, so […]

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Extinction and Species Declines:Defaunation in the Anthropocene

Mon, 18 Aug 2014 10:35:52 +0000

We are in the grips of a mass extinction. There have been mass extinctions throughout evolutionary history, what makes this one different is that we’re the ones causing it. A recent review paper from GEE’s Dr Ben Collen discusses the current loss of biodiversity and suggests that our main concerns are species and population declines, […]

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Defaunation in the Anthropocene
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Evolving Endemism in East Africa’s Sky Islands

Fri, 08 Aug 2014 14:16:32 +0000

The World’s biodiversity is not evenly distributed. Some regions are hot spots for species richness, and biologists have been trying better to understand why these regions are special and what drives evolution and diversification. A recent paper by GEE’s Dr Julia Day and recent PhD graduate Dr Siobhan Cox, investigated the diversification of White-Eye Birds […]

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Predicting Extinction Risk:The Importance of Life History and Demography

Mon, 28 Jul 2014 14:46:17 +0000

The changing climate is no longer simply a concern for the future, it is a reality. Understanding how the biodiversity that we share our planet with will respond to climate change is a key step in developing long-term strategies to conserve it. Recent research by UCL CBER’s Dr Richard Pearson identifies the key characteristics that […]

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The Importance of Life History and Demography
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It Pays to Be Different:Evolutionary Distinctiveness and Conservation Priorities

Tue, 15 Jul 2014 13:15:25 +0000

The world is currently experiencing an extinction crisis. A mass extinction on a scale not seen since the dinosaurs. While conservationists work tirelessly to try and protect the World’s biodiversity, it will not be possible to save everything, and it is important to focus conservation efforts intelligently. Evolutionary distinctiveness is a measure of how isolated […]

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Evolutionary Distinctiveness and Conservation Priorities
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Prof Jürg Bähler publishes lead article on Fission Yeast in Cell journal

1 November 2012

Quantitative Analysis of Fission Yeast Transcriptomes and Proteomes in Proliferating and Quiescent Cells

Samuel Marguerat, Alexander Schmidt, Sandra Codlin, Wei Chen, Ruedi Aebersold, and Jürg Bähler

This article reports cellular numbers for all RNAs and most proteins in proliferating and non-dividing cells of fission yeast. Most mRNAs are expressed at only 1-10 copies/cell, while corresponding proteins show greater abundance and range, from less than 100 to over 1 million copies/cell. Only a minority of long non-coding RNAs are expressed at >1 copy/cell. In the smaller non-dividing cells, the protein content changes substantially and RNA concentrations greatly decrease. These RNA and protein concentrations inform about cell regulation and function.

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Page last modified on 01 nov 12 16:58