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The Importance of Size in the Evolution of Complexity in Ants

Tue, 16 Sep 2014 10:14:37 +0000

Ants are amongst the most abundant and successful species on Earth. They live in complex, cooperative societies, construct elaborate homes and exhibit many of the hallmarks of our own society. Some ants farm crops, others tend livestock. Many species have a major impact on the ecosystems they live in, dispersing seeds, consuming huge quantities of […]

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Understanding Catfish Colonisation and Diversification in The Great African Lakes

Fri, 05 Sep 2014 10:29:42 +0000

Why some regions or habitats contain vast, diverse communities of species, whilst others contain only relatively few species, continues to be the subject of scientific research attempting to understand the processes and conditions that allow and adaptive radiation. The Great African Lakes exist as freshwater ‘islands’, with spectacularly high levels of biodiversity and endemism. They […]

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Sex Differentiation Begins During Early Development

Wed, 27 Aug 2014 14:04:57 +0000

Males and females look different from each other, and these sexual dimorphisms are the result, largely, of sex differences in the expression of certain genes. Typically, scientists have studied sexual dimorphism in sexually mature adult animals, as this is the lifestage where differences are most apparent. However, many sex-specific phenotypes arise from sex-biased development, so […]

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Extinction and Species Declines:Defaunation in the Anthropocene

Mon, 18 Aug 2014 10:35:52 +0000

We are in the grips of a mass extinction. There have been mass extinctions throughout evolutionary history, what makes this one different is that we’re the ones causing it. A recent review paper from GEE’s Dr Ben Collen discusses the current loss of biodiversity and suggests that our main concerns are species and population declines, […]

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Defaunation in the Anthropocene
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Evolving Endemism in East Africa’s Sky Islands

Fri, 08 Aug 2014 14:16:32 +0000

The World’s biodiversity is not evenly distributed. Some regions are hot spots for species richness, and biologists have been trying better to understand why these regions are special and what drives evolution and diversification. A recent paper by GEE’s Dr Julia Day and recent PhD graduate Dr Siobhan Cox, investigated the diversification of White-Eye Birds […]

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GEE team led by Dr Nik Maniatis makes important progress on way to dissect the genetics of complex inheritance

12 December 2011

A GEE team led by Dr Nik Maniatis [Heather Elding (PhD student), Winston Lau (PostDoc), Prof Dallas Swallow and Nik] have recently made important progress on the way to dissect the genetics of complex inheritance.

Published last week in The American Journal of Human Genetics, the newly identified genes have filled in some of the missing gaps for Crohn’s Disease (CD), as well as showing that different CD patients carry different sets of causal variants. The findings could pave the way for personalised treatment and also lead to improved understanding of how complex diseases are inherited. The team used UK data provided by the Wellcome Trust Case Control Consortium. Using a powerful mapping technique based on refined genetic maps, they managed to pinpoint the plausible causal locations. All the locations were replicated using independent US data.

Links: 

UCL's Press Release:  “Personalised treatment for Crohn’s Disease a step closer following gene mapping” here

The paper can be found here

Page last modified on 12 dec 11 10:43