GEE News Publication
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- Obituary: Professor David Wilkie, born 6th August 1923, died 3rd March 2013
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- Animal model of human evolution indicates thick hair mutation emerged 30,000 years ago
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- Orgin of life emerged from cell membrane bioenergetics
- More than 200 hundred genes identified for Crohn’s Disease by the Maniatis group at GEE
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- Prof Jürg Bähler publishes lead article on Fission Yeast in Cell journal
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- GEE team led by Dr Nik Maniatis makes important progress on way to dissect the genetics of complex inheritance
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- Indians share milk-digesting trait with Europeans: new Cambridge study published in collaboration with GEE's Profs Mark Thomas and Dallas Swallow
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GEE team led by Dr Nik Maniatis makes important progress on way to dissect the genetics of complex inheritance
12 December 2011
A GEE team led by Dr Nik Maniatis [Heather Elding (PhD student), Winston Lau (PostDoc), Prof Dallas Swallow and Nik] have recently made important progress on the way to dissect the genetics of complex inheritance.
Published last week in The American Journal of Human Genetics, the newly identified genes have filled in some of the missing gaps for Crohn’s Disease (CD), as well as showing that different CD patients carry different sets of causal variants. The findings could pave the way for personalised treatment and also lead to improved understanding of how complex diseases are inherited. The team used UK data provided by the Wellcome Trust Case Control Consortium. Using a powerful mapping technique based on refined genetic maps, they managed to pinpoint the plausible causal locations. All the locations were replicated using independent US data.
Links:
UCL's Press Release: “Personalised treatment for Crohn’s Disease a step closer following gene mapping” here
The paper can be found here
Page last modified on 12 dec 11 10:43
