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PREDICTS Project: Global Analysis Reveals Massive Biodiversity Losses

Thu, 21 May 2015 14:44:08 +0000

The changing climate is only one of a myriad of pressures faced by global biodiversity – we are also changing habitats and altering land-use on an unprecedented scale. The first global analysis published from the PREDICTS project reveals the striking global effect of land-use change on local biodiversity patterns, and highlights the importance of future […]

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GEE team led by Dr Nik Maniatis makes important progress on way to dissect the genetics of complex inheritance

12 December 2011

A GEE team led by Dr Nik Maniatis [Heather Elding (PhD student), Winston Lau (PostDoc), Prof Dallas Swallow and Nik] have recently made important progress on the way to dissect the genetics of complex inheritance.

Published last week in The American Journal of Human Genetics, the newly identified genes have filled in some of the missing gaps for Crohn’s Disease (CD), as well as showing that different CD patients carry different sets of causal variants. The findings could pave the way for personalised treatment and also lead to improved understanding of how complex diseases are inherited. The team used UK data provided by the Wellcome Trust Case Control Consortium. Using a powerful mapping technique based on refined genetic maps, they managed to pinpoint the plausible causal locations. All the locations were replicated using independent US data.

Links: 

UCL's Press Release:  “Personalised treatment for Crohn’s Disease a step closer following gene mapping” here

The paper can be found here

Page last modified on 12 dec 11 10:43