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Synthetic Biology and Conservation

Mon, 07 Jul 2014 16:20:18 +0000

Synthetic biology, a hybrid between Engineering and Biology, is an emerging field of research promising to change the way we think about manufacturing, medicine, food production, and even conservation and sustainability. A review paper released this month in Oryx, authored by Dr Kent Redford, Professor William Adams, Dr Rob Carlson, Bertina Ceccarelli and CBER’s Professor [...]

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Measure Twice, Cut Once: Quantifying Biases in Sexual Selection Studies

Wed, 25 Jun 2014 10:44:30 +0000

Bateman’s principles are conceptually quite simple, but form the basis of our understanding of sexual selection across the animal kingdom. First proposed in 1948, Bateman’s three principles posit that sexual selection is more intense in males than in females for three reasons: 1) males show more variability in the number of mates they have (mating [...]

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Technology for Nature?

Mon, 16 Jun 2014 13:23:54 +0000

Many of our greatest technological advances have tended to mark disaster for nature. Cars guzzle fossil fuels and contribute to global warming; industrialised farming practices cause habitat loss and pollution; computers and mobile phones require harmful mining procedures to harvest rare metals. But increasingly, ecologists and conservation biologists are asking whether we can use technology [...]

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Nice Flies Don’t Finish Last: Meiotic Drive and Sexual Selection in Stalk-Eyed Flies

Thu, 12 Jun 2014 15:54:47 +0000

While it might seem as though our genes are all working together for our own good, some of them are actually rather selfish. Scientists have known about ‘selfish genetic elements’ for nearly a century, but research to understand their behaviour and effects is ongoing. Recent research in GEE reveals how sexually selected traits are signalling [...]

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Finding a Place to Call Home: Translocation and the Plight of the Hihi

Fri, 16 May 2014 13:13:56 +0000

Climate change alters how climate is distributed both geographically and temporally. Over the coming decades, for species sensitive to climatic variables, it may become a case of ‘relocate or die’ – those species that are not able to shift their populations from old, unsuitable habitat into newly emerging suitable habitat, in line with climate change, [...]

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GEE team led by Dr Nik Maniatis makes important progress on way to dissect the genetics of complex inheritance

12 December 2011

A GEE team led by Dr Nik Maniatis [Heather Elding (PhD student), Winston Lau (PostDoc), Prof Dallas Swallow and Nik] have recently made important progress on the way to dissect the genetics of complex inheritance.

Published last week in The American Journal of Human Genetics, the newly identified genes have filled in some of the missing gaps for Crohn’s Disease (CD), as well as showing that different CD patients carry different sets of causal variants. The findings could pave the way for personalised treatment and also lead to improved understanding of how complex diseases are inherited. The team used UK data provided by the Wellcome Trust Case Control Consortium. Using a powerful mapping technique based on refined genetic maps, they managed to pinpoint the plausible causal locations. All the locations were replicated using independent US data.

Links: 

UCL's Press Release:  “Personalised treatment for Crohn’s Disease a step closer following gene mapping” here

The paper can be found here

Page last modified on 12 dec 11 10:43