GEE News Publication

City living helped humans evolve immunity to TB

1 October 2010

New research from Professor Mark Thomas of the UCL Research Department of Genetics, Evolution and Environment (GEE) has found that a genetic variant which reduces the chance of contracting diseases such as tuberculosis and leprosy is more prevalent in populations with long histories of urban living.


The research, published in the journal Evolution, shows that in areas with a long history of urban settlements, today’s inhabitants are more likely to possess the genetic variant which provides resistance to infection. 

Professor Thomas said: “The results show that the protective variant is found in nearly everyone from the Middle East to India and in parts of Europe where cities have been around for thousands of years”

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