dr roland schaette
Research
Themes
- Dr
- Roland
- Schaette
- Dr Roland Schaette
- r.schaette@ucl.ac.uk
- https://iris.ucl.ac.uk/images/profile/RSCHA01.jpg
- 2008-11-01
- RESSRA
- 2008-11-01
- 1
- Senior Research Associate
- HP
- The Ear Institute
- FBRS
- Faculty of Brain Sciences
- 2008-11-01
Research Summary
In order to gain a better understanding of tinnitus and how to treat it, my research focuses on the following questions:
- Can tinnitus be linked to a specific type or pattern of cochlear damage?
- How can cochlear damage lead to the development of tinnitus-related neural activity patterns in the auditory system?
- How does the auditory system react and adapt to altered input, for example after hearing loss through damage to the cochlea? And which mechanisms of activity dependent neuronal plasticity are involved?
- How can plastic changes after hearing loss be reverted through acoustic or electric stimulation?
These questions are addressed using theoretical models, animal studies, and studies with human subjects.
Tinnitus with a normal audiogram: physiological evidence for hidden hearing loss and computational model.
Acoustic stimulation treatments against tinnitus could be most effective when tinnitus pitch is within the stimulated frequency range.
The principal neurons of the medial nucleus of the trapezoid body and NG2(+) glial cells receive coordinated excitatory synaptic input.
Predicting tinnitus pitch from patients' audiograms with a computational model for the development of neuronal hyperactivity.
Development of hyperactivity after hearing loss in a computational model of the dorsal cochlear nucleus depends on neuron response type.
Course of hearing loss and occurrence of tinnitus.
Development of tinnitus-related neuronal hyperactivity through homeostatic plasticity after hearing loss: a computational model
Spike-train variability of auditory neurons in vivo: dynamic responses follow predictions from constant stimuli.
Academic Background
-
Award YearQualificationInstitution
-
2007PhDHumboldt-Universität Berlin
-
2002Dip.Humboldt-Universität Berlin
Biography
“A spider’s web is hidden in one ear, and in the other, a cricket sings throughout the night.” This is how Michelangelo described his experience of hearing loss and tinnitus. The goal of my research is to find the cricket, to understand how tinnitus arises, in order to find new ways of treating it.
I started doing research on tinnitus in 2003, and since November 2008, I have been working in London at the UCL Ear Institute as the British Tinnitus Association Senior Research Associate.
My motivation to work on tinnitus is based on my interest in the auditory system, my fascination with neuronal plasticity, and my own experience of tinnitus (which is fortunately rather benign).
Page last modified on 02 nov 11 15:58
