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UCL Ear Institute

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Dr Jennifer Linden

Dr Jennifer Linden

Address

UCL Ear Institute
332 Gray's Inn Rd
London
WC1X 8EE

Appointments

  • Reader in Neuroscience
    The Ear Institute
    Faculty of Brain Sciences

Joined UCL

2004-09-01

Human beings effortlessly perform complex feats of sound perception and auditory learning; for example, identifying new friends on the telephone just from the way they say hello; predicting a family member's arrival home by the sound of the car alone; or recognizing music from mere snippets heard while flipping through channels on the radio. These everyday yet remarkable abilities depend on listening and learning mechanisms within the brain, not just hearing mechanisms within the ear.  Research in my laboratory is aimed at understanding these brain mechanisms of listening and learning, especially in the auditory cortex and thalamus.  Key questions include:

* How is auditory information transformed within thalamocortical circuits?

* What roles do the components of thalamocortical circuits play in sound perception and auditory learning?

* How is central auditory processing of auditory information affected by acoustic experience?

* How is central auditory processing altered in brain disorders affecting auditory perception?

Research in the laboratory is interdisciplinary, involving a combination of electrophysiological, behavioural, and computational techniques. We work primarily with mice, including mouse models of conditions such as tinnitus, schizophrenia, and developmental language disorder in humans.  Our work benefits from our affiliations with the UCL Ear Institute and the Department of Neuroscience, Physiology and Pharmacology; we also have collaborative links with the Gatsby Computational Neuroscience Unit, the Department of Cell and Developmental Biology, the Institute of Ophthalmology, and other academic research units at UCL.

Award year Qualification Institution
1999 PhD
Doctor of Philosophy
Computation and Neural Systems
California Institute of Technology
1991 BA
Bachelor of Arts
Biology
Harvard University
04-06 CLTHE_1
Certificate in Learning and Teaching in HE Part 1
Academic studies in Higher Education
University College London

I'm interested in how central auditory processing works normally, and how it is disrupted in brain disorders affecting hearing.  I use mainly electrophysiological techniques but also behavioural, molecular and computational modelling methods.  UCL is simply the one of the best environments in the world for my research, given the depth of expertise across biological and computational sciences.  The UCL Ear Institute is just one outstanding component of a very rich research environment.

Keywords

Auditory|*|Auditory processing|*|Auditory system disorders|*|Behaviour|*|Brain|*|Coding|*|Computational methods|*|Computational modeling|*|Computational models|*|Discrimination learning|*|Electrophysiology|*|Extracellular recording - acute|*|Extracellular recording - chronic|*|Hearing|*|Learning|*|Mouse|*|Neocortex|*|Neural Circuits/Networks|*|Neurophysiology|*|Operant conditioning|*|Perception|*|Plasticity|*|Role of auditory cortex in hearing and learning|*|Silicon probe recording|*|Transgenic mice