prof jonathan ashmore
Research
Themes
Contacts
- Prof
- Jonathan
- Felix
- Ashmore
- Prof Jonathan Ashmore
- Tel: 020 7679 2141
- Ex: 32141
- Fax: 020 7813 0530
- j.ashmore@ucl.ac.uk
- Website
- https://iris.ucl.ac.uk/images/profile/JFASH40.jpg
- 1996-08-01
Address
- 812
- Department of Neuroscience, Physiology and Pharmacology
- University College London
- London
- WC1E 6BT
Appointment
- ACAPRO
- 1996-08-01
- 1
- Bernard Katz Professor of Biophysics
- NPP
- Neuroscience, Physiology & Pharmacology
- F1
- Div of Biosciences
Joined UCL
- 1996-08-01
Research Summary
My work addresses a variety of cellular mechanisms of hearing. Using a variety of biophysical techniques I work on the mechanisms of electromotility in cochlear outer hair cells. Using confocal imaging I have been working on the mechanisms of synaptic release at the ribbon synapse of the inner hair cells, combining electrophysiology and multiphoton imaging. Using large scale computational models I work on the patterning of electrical current flow in the cochlea during stimulation by sound. More recently I have become interested in potassium channel function in early auditory processing and the nature and origin of tinnitus.Research Activities
- 1465
- Cellular Mechanisms of Hearing
- 1128
- Potassium homeostasis in the cochlea and deafness
- 527
- The active role of outer hair cells
1 - 10 of 78 Publications
TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells
Journal article
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Pushing the envelope of sound.
Journal article
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Identification of simultaneous calcium entry sites in cochlear inner hair cells of the adult mouse
Conference
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The afferent synapse
Chapter
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Publisher: Oxford University Press
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Publisher: World Scientific
The role of potassium recirculation in cochlear amplification.
Journal article
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Additional Information
- Ageing
- Atomic force microscopy
- Auditory system disorders
- Brain slice physiology
- Calcium imaging
- Cell culture
- Cellular mechanisms of hearing
- Computational methods
- Computational modeling
- Computational models
- Confocal microscopy
- Deafness
- Electrophysiological recording techniques
- Electrophysiology
- Exocytosis
- Fluorescence microscopy techniques
- Genetic manipulation (including knockout/knockin)
- Genetics
- Hearing
- Hearing and balance
- Image analysis Intracellular recording
- Ion channels
- Light microscopic techniques
- Mouse
- Multi-photon imaging
- Neuroscience
- Optical imaging
- Pharmacology
- Sensory transduction
- Single-channel recording
- Synapse
Collaborators
- ARGAR51
- prof tony gardner-medwin
- SJDAW90
- dr sally dawson
Page last modified on 30 nov 11 10:43
