Publications
Number of items: 53.
2013
| Linden Phillips, L and Bitner-Glindzicz, M and Lench, N and Steel, KP and Langford, C and Dawson, SJ and Davis, A and Simpson, S and Packer, C (2013) The future role of genetic screening to detect newborns at risk of childhood-onset hearing loss. Int J Audiol , 52 (2) 124 - 133. 10.3109/14992027.2012.733424. |
| Nolan, LS and Cadge, BA and Gomez-Dorado, M and Dawson, SJ (2013) A functional and genetic analysis of SOD2 promoter variants and their contribution to age-related hearing loss. Mech Ageing Dev 10.1016/j.mad.2013.02.009. |
| Nolan, LS and Maier, H and Hermans-Borgmeyer, I and Girotto, G and Ecob, R and Pirastu, N and Cadge, BA and Hübner, C and Gasparini, P and Strachan, DP and Davis, A and Dawson, SJ (2013) Estrogen-related receptor gamma and hearing function: evidence of a role in humans and mice. Neurobiol Aging , 34 (8) 2077.e1 - 2077.e9. 10.1016/j.neurobiolaging.2013.02.009. |
| Nolana, LS and Maierb, H and Hermans-Borgmeyerc, I and Girottod, G and Ecoba, R and Pirastud, N and Cadgea, BA and Hübnere, C and Gasparinid, P and Strachanf, DP and Davisa, A and Dawson, SJ (2013) ESRRG and hearing function; evidence of a role in humans and mice. Neurobiology of Aging (In press). |
2012
| Dawson, SJ (2012) The genetics of ototoxicity. ENT and Audiology News , 21 (1) 70 - 73. |
2011
| Al-Malky, G and Suri, R and Dawson, SJ and Sirimanna, T and Kemp, D (2011) Aminoglycoside antibiotics cochleotoxicity in paediatric cystic fibrosis (CF) patients: A study using extended high-frequency audiometry and distortion product otoacoustic emissions. INT J AUDIOL , 50 (2) 112 - 122. 10.3109/14992027.2010.524253. |
| Towers, ER and Kelly, JJ and Sud, R and Gale, JE and Dawson, SJ (2011) Caprin-1 is a target of the deafness gene Pou4f3 and is recruited to stress granules in cochlear hair cells in response to ototoxic damage. J CELL SCI , 124 (7) 1145 - 1155. 10.1242/jcs.076141. |
2010
| DAWSON, S (2010) The Role of Genetics in Age-Related Hearing Loss. ENT & Audiology News , 19 (4) 100 - 102. |
2007
| Nolan, LS and Jagutpal, SS and Cadge, BA and Woo, P and Dawson, SJ (2007) Identification and functional analysis of common sequence variants in the DFNA15 gene, Brn-3c. GENE , 400 (1-2) 89 - 97. 10.1016/j.gene.2007.05.023. |
2005
| Sud, R and Jones, CM and Banfi, S and Dawson, SJ (2005) Transcriptional regulation by Barh11 and Brn-3c in organ of corti derived cell lines. MOL BRAIN RES , 141 (2) 174 - 180. 10.1016/j.molbrainres.2005.09.007. |
| Sud, R and Jones, CM and Banfi, S and Dawson, SJ (2005) Transcriptional regulation by Barhl1 and Brn-3c in organ of corti derived cell lines. Molecular Brain Research , 141 (2) 174 - 180. |
| Sud, R. and Jones, C.M. and Banfi, S. and Dawson, S.J. (2005) Transcriptional regulation by Barhl1 and Brn-3c in organ of corti derived cell lines. Molecular Brain Research , 141 (2) pp. 174-180. 10.1016/j.molbrainres.2005.09.007. |
2004
| Clough, RL and Sud, R and Davis-Silberman, N and Hertzano, R and Avraham, KB and Holley, M and Dawson, SJ (2004) Brn-3c (POU4F3) regulates BDNF and NT-3 promoter activity. BIOCHEM BIOPH RES CO , 324 (1) 372 - 381. 10.1016/j.bbrc.2004.09.074. |
2003
| Weiss, S and Gottfried, I and Mayrose, I and Khare, SL and Xiang, MQ and Dawson, SJ and Avraham, KB (2003) The DFNA15 deafness mutation affects POU4F3 protein stability, localization, and transcriptional activity. MOL CELL BIOL , 23 (22) 7957 - 7964. 10.1128/MCB.23.22.7957-7964.2003. |
2002
| Lindahl, GE and Chambers, RC and Papakrivopoulou, J and Dawson, SJ and Jacobsen, MC and Bishop, JE and Laurent, GJ (2002) Activation of fibroblast procollagen alpha 1(I) transcription by mechanical strain is transforming growth factor-beta-dependent and involves increased binding of CCAAT-binding factor (CBF/NF-Y) at the proximal promoter. J BIOL CHEM , 277 (8) 6153 - 6161. 10.1074/jbc.M108966200. |
2000
| Avraham, KB and Khare, SL and Xiang, M and Dawson, SJ and Weiss, S (2000) The biological basis for autosomal dominant nonsyndromic hearing loss DFNA15: expression, DNA binding and transcription properties. Presented at: 50th Annual American Society of Human Genetics (ASHG) Meeting, Pennsylvania Convention Center, Philadelphia, PA. |
1998
| Dawson, SJ and Palmer, RD and Morris, PJ and Latchman, DS (1998) Functional role of position 22 in the homeodomain of Brn-3 transcription factors. NEUROREPORT , 9 (10) 2305 - 2309. |
| Gay, RD and Dawson, SJ and Murphy, WJ and Russell, SW and Latchman, DS (1998) Activation of the iNOS gene promoter by Brn-3 POU family transcription factors is dependent upon the octamer motif in the promoter. BBA-GENE STRUCT EXPR , 1443 (3) 315 - 322. |
| Liu, YZ and Lee, IK and Locke, I and Dawson, SJ and Latchman, DS (1998) Adjacent proline residues in the inhibitory domain of the Oct-2 transcription factor play distinct functional roles. NUCLEIC ACIDS RES , 26 (10) 2464 - 2472. |
| Smith, MD and Dawson, SJ and Boxer, LM and Latchman, DS (1998) The N-terminal domain unique to the long form of the Brn-3a transcription factor is essential to protect neuronal cells from apoptosis and for the activation of Bcl-2 gene expression. NUCLEIC ACIDS RES , 26 (18) 4100 - 4107. |
1997
| Deans, ZC and Dawson, SJ and Kilimann, MW and Wallace, D and Wilson, MC and Latchman, DS (1997) Differential regulation of genes encoding synaptic proteins by the Oct-2 transcription factor. MOL BRAIN RES , 51 (1-2) 1 - 7. |
| Gay, RD and Dawson, SJ and Latchman, DS (1997) The different inhibitory domains of the Oct-2 transcription factor have distinct functional activities. FEBS LETT , 416 (2) 135 - 138. |
| Morris, PJ and Dawson, SJ and Wilson, MC and Latchman, DS (1997) A single residue within the homeodomain of the Brn-3 POU family transcription factors determines whether they activate or repress the SNAP-25 promoter. NEUROREPORT , 8 (8) 2041 - 2045. |
| Smith, MD and Dawson, SJ and Latchman, DS (1997) Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factor. J BIOL CHEM , 272 (2) 1382 - 1388. |
| Smith, MD and Dawson, SJ and Latchman, DS (1997) The Brn-3a transcription factor induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins. MOL CELL BIOL , 17 (1) 345 - 354. |
| Smith, MD and Morris, PJ and Dawson, SJ and Schwartz, ML and Schlaepfer, WW and Latchman, DS (1997) Coordinate induction of the three neurofilament genes by the Brn-3a transcription factor. J BIOL CHEM , 272 (34) 21325 - 21333. |
1996
| BudhramMahadeo, V and Morris, PJ and Lakin, ND and Dawson, SJ and Latchman, DS (1996) The different activities of the two activation domains of the Brn-3a transcription factor are dependent on the context of the binding site. J BIOL CHEM , 271 (15) 9108 - 9113. |
| Dawson, SJ and Liu, YZ and Rodel, B and Moroy, T and Latchman, DS (1996) The ability of POU family transcription factors to activate or repress gene expression is dependent on the spacing and context of their specific response elements. BIOCHEM J , 314 439 - 443. |
| Dawson, SJ and Morris, PJ and Latchman, DS (1996) A single amino acid change converts an inhibitory transcription factor into an activator. J BIOL CHEM , 271 (20) 11631 - 11633. |
| Deans, Z and Dawson, SJ and Xie, JL and Young, AP and Wallace, D and Latchman, DS (1996) Differential regulation of the two neuronal nitric-oxide synthase gene promoters by the Oct-2 transcription factor. J BIOL CHEM , 271 (50) 32153 - 32158. |
| Liu, YZ and Dawson, SJ and Gerster, T and Friedl, E and Pengue, G and Matthias, P and Lania, L and Latchman, DS (1996) The ability of the inhibitory domain of the POU family transcription factor Oct-2 to interfere with promoter activation by different classes of activation domains is dependent upon the nature of the basal promoter elements. J BIOL CHEM , 271 (34) 20853 - 20860. |
| Liu, YZ and Dawson, SJ and Latchman, DS (1996) Alternative splicing of the Brn-3a and Brn-3b transcription factor RNAs is regulated in neuronal cells. J MOL NEUROSCI , 7 (1) 77 - 85. |
| Morris, PJ and Lakin, ND and Dawson, SJ and Ryabinin, AE and Kilimann, MW and Wilson, MC and Latchman, DS (1996) Differential regulation of genes encoding synaptic proteins by members of the Brn-3 subfamily of POU transcription factors. MOL BRAIN RES , 43 (1-2) 279 - 285. |
1995
| Deans, L and Dawson, SJ and Buttery, L and Polak, JM and Wallace, D and Latchman, DS (1995) Direct evidence that the POU family transcription factor Oct-2 represses the cellular tyrosine hydroxylase gene in neuronal cells. J MOL NEUROSCI , 6 (3) 159 - 167. |
| GREEN, FR and LANE, A and THOMAS, AE and DAWSON, S and MILLER, G and HAMSTEN, A and HUMPHRIES, SE (1995) GENE ENVIRONMENT INTERACTIONS AND THE RISK OF THROMBOSIS. In: Woodford, FP and Davignon, J and Sniderman, A, (eds.) ATHEROSCLEROSIS X. (pp. 805 - 807). ELSEVIER SCIENCE PUBL B V |
| Ye, S and Green, FR and Scarabin, PY and Nicaud, V and Bara, L and Dawson, SJ and Humphries, SE and Evans, A and Luc, G and Cambou, JP (1995) The 4G/5G genetic polymorphism in the promoter of the plasminogen activator inhibitor-1 (PAI-1) gene is associated with differences in plasma PAI-1 activity but not with risk of myocardial infarction in the ECTIM study. Etude CasTemoins de I'nfarctus du Mycocarde. Thromb Haemost , 74 (3) 837 - 841. |
| YE, S and GREEN, FR and SCARABIN, PY and NICAUD, V and BARA, L and DAWSON, SJ and HUMPHRIES, SE and EVANS, A and LUC, G and CAMBOU, JP and ARVEILER, D and HENNEY, AM and CAMBIEN, F (1995) THE 4G/5G GENETIC-POLYMORPHISM IN THE PROMOTER OF THE PLASMINOGEN-ACTIVATOR INHIBITOR-1 (PAI-1) GENE IS ASSOCIATED WITH DIFFERENCES IN PLASMA PAI-1 ACTIVITY BUT NOT WITH RISK OF MYOCARDIAL-INFARCTION IN THE ECTIM STUDY. THROMB HAEMOSTASIS , 74 (3) 837 - 841. |
1994
| DAWSON, SJ and YOON, SO and CHIKARAISHI, DM and LILLYCROP, KA and LATCHMAN, DS (1994) THE OCT-2 TRANSCRIPTION FACTOR REPRESSES TYROSINE-HYDROXYLASE EXPRESSION VIA A HEPTAMER TAATGARAT-LIKE MOTIF IN THE GENE PROMOTER. NUCLEIC ACIDS RES , 22 (6) 1023 - 1028. |
| LILLYCROP, KA and DAWSON, SJ and ESTRIDGE, JK and GERSTER, T and MATTHIAS, P and LATCHMAN, DS (1994) REPRESSION OF A HERPES-SIMPLEX VIRUS IMMEDIATE-EARLY PROMOTER BY THE OCT-2 TRANSCRIPTION FACTOR IS DEPENDENT ON AN INHIBITORY REGION AT THE N-TERMINUS OF THE PROTEIN. MOL CELL BIOL , 14 (11) 7633 - 7642. |
1993
| DAWSON, SJ and WIMAN, B and HAMSTEN, A and GREEN, F and HUMPHRIES, S and HENNEY, AM (1993) THE 2 ALLELE SEQUENCES OF A COMMON POLYMORPHISM IN THE PROMOTER OF THE PLASMINOGEN-ACTIVATOR INHIBITOR-1 (PAI-1) GENE RESPOND DIFFERENTLY TO INTERLEUKIN-1 IN HEPG2 CELLS. J BIOL CHEM , 268 (15) 10739 - 10745. |
1992
| DAWSON, S and HENNEY, A (1992) THE STATUS OF PAI-1 AS A RISK FACTOR FOR ARTERIAL AND THROMBOTIC DISEASE - A REVIEW. ATHEROSCLEROSIS , 95 (2-3) 105 - 117. |
| Humphries, SE and Green, FR and Temple, A and Dawson, S and Henney, A and Kelleher, CH and Wilkes, H and Meade, TW and Wiman, B and Hamsten, A (1992) Genetic factors determining thrombosis and fibrinolysis. Ann Epidemiol , 2 (4) 371 - 385. |
| HUMPHRIES, SE and LANE, A and DAWSON, S and GREEN, FR (1992) THE STUDY OF GENE-ENVIRONMENT INTERACTIONS THAT INFLUENCE THROMBOSIS AND FIBRINOLYSIS - GENETIC-VARIATION AT THE LOCI FOR FACTOR-VII AND PLASMINOGEN-ACTIVATOR INHIBITOR-1. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE , 116 (12) 1322 - 1329. |
| THOMAS, AE and GREEN, FR and DAWSON, SJ and LANE, A and HENNEY, AM and KELLEHER, CH and WILKES, HC and BRENNAN, PJ and CRUICKSHANK, JK and HAMSTEN, A and WIMAN, B and MEADE, TW and HUMPHRIES, SE (1992) POSSIBILITIES OF DNA ANALYSIS FOR THE DETECTION OF PREDISPOSITION TO THROMBOTIC DISEASE. ANN NY ACAD SCI , 667 332 - 342. |
| THOMAS, AE and GREEN, FR and DAWSON, SJ and LANE, A and HENNEY, AM and KELLEHER, CH and WILKES, HC and BRENNAN, PJ and CRUICKSHANK, JK and HAMSTEN, A and WIMAN, B and MEADE, TW and HUMPHRIES, SE (1992) POSSIBILITIES OF DNA ANALYSIS FOR THE DETECTION OF PREDISPOSITION TO THROMBOTIC DISEASE. PLASMINOGEN ACTIVATION IN FIBRINOLYSIS, IN TISSUE REMODELING, AND IN DEVELOPMENT , 667 332 - 342. |
1991
| DAWSON, S and HAMSTEN, A and WIMAN, B and HENNEY, A and HUMPHRIES, S (1991) GENETIC-VARIATION AT THE PLASMINOGEN-ACTIVATOR INHIBITOR-1 LOCUS IS ASSOCIATED WITH ALTERED LEVELS OF PLASMA PLASMINOGEN-ACTIVATOR INHIBITOR-1 ACTIVITY. ARTERIOSCLER THROMB , 11 (1) 183 - 190. |
| DAWSON, SJ and WIMAN, B and HAMSTEN, A and GREEN, F and HENNEY, AM and HUMPHRIES, S (1991) A COMMON POLYMORPHISM IN THE PLASMINOGEN-ACTIVATOR INHIBITOR-1 (PAI-1) PROMOTER SHOWS ALLELE SPECIFIC DIFFERENTIAL BINDING TO HEPG2 NUCLEAR EXTRACTS AND IS ASSOCIATED WITH ALTERED PLASMA PAI-1 LEVELS. AM J HUM GENET , 49 (4) 426 - 426. |
| DAWSON, SJ and WIMAN, B and HAMSTEN, A and GREEN, F and HENNEY, AM and HUMPHRIES, S (1991) ALLELE SPECIFIC DIFFERENTIAL BINDING OF HEPG2 NUCLEAR EXTRACTS TO A COMMON POLYMORPHISM IN THE PLASMINOGEN-ACTIVATOR INHIBITOR-1 (PAI-1) PROMOTER WHICH IS ASSOCIATED WITH ALTERED PLASMA PAI-1 LEVELS. THROMB HAEMOSTASIS , 65 (6) 806 - 806. |
| HENNEY, AM and GREEN, FR and DAWSON, SJ and YE, S and LANE, A and HUMPHRIES, SE and SCARABIN, PY and CAMBIEN, F and EVANS, A and CAMBOU, JP and ARVEILER, D and BARA, L (1991) PAI-1 AND FACTOR-VII GENE POLYMORPHISMS AND ASSOCIATION WITH PLASMA-LEVELS IN THE ECTIM STUDY, A MULTICENTER, CASE-CONTROL STUDY OF MYOCARDIAL-INFARCTION. THROMB HAEMOSTASIS , 65 (6) 993 - 993. |
| HUMPHRIES, SE and GREEN, F and DAWSON, S and HAMSTEN, A (1991) INTERACTION BETWEEN GENOTYPE AND ENVIRONMENTAL-FACTORS IN THE DEVELOPMENT OF ATHEROSCLEROTIC-THROMBOTIC ARTERIAL DISEASES. THROMB HAEMOSTASIS , 65 (6) 816 - 816. |
1990
| DAWSON, S and HAMSTEN, A and WIMAN, B and HENNEY, A and HUMPHRIES, S (1990) GENETIC-VARIATION AT THE PLASMINOGEN-ACTIVATOR INHIBITOR-1 (PAI-1) LOCUS. FIBRINOLYSIS , 4 51 - 53. |
| DAWSON, SJ and HENNEY, AM and HUMPHRIES, S and HAMSTEN, A (1990) USE OF PCR TO GENOTYPE A POLYMORPHIC DINUCLEOTIDE REPEAT WITHIN THE PAI-1 GENE IN PATIENTS WITH A RECENT MI. J MED GENET , 27 (3) 207 - 207. |
| POWELL, JT and BASHIR, A and DAWSON, S and VINE, N and HENNEY, AM and HUMPHRIES, SE and GREENHALGH, RM (1990) GENETIC-VARIATION ON CHROMOSOME-16 IS ASSOCIATED WITH ABDOMINAL AORTIC-ANEURYSM. CLIN SCI , 78 (1) 13 - 16. |
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